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Relationship between the weight-adjusted-waist index and kidney stone: a population-based study

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A Letter to the Editor to this article was published on 20 December 2023

Abstract

Background

At present, a growing number of studies have shown a positive association between obesity and kidney stone, while traditional anthropometric measures, such as body mass index (BMI) and Waist circumference (WC), have limited ability to assess the risk of kidney stone. Therefore, this study aimed to investigate the association between the weight-adjusted-waist index (WWI) and the risk of kidney stone.

Method

Data from the National Health and Nutrition Examination Survey (NHANES) between 2009 and 2016 were used. A total of 17,292 participants from NHANES were included in the study. Multivariate logistic regression and restricted cubic splines (RCS) were used to investigate the relationship between WWI and kidney stone. Interaction analysis was performed for subgroups to verify the results. Meanwhile, the receiver operating characteristic curve (ROC) was used to analyze the efficacy of different anthropometric indices in predicting the risk of kidney stone.

Results

After adjusting for potential confounding factors, we found a positive and independent association between kidney stone and WWI. After adjusting for all covariates, a one-unit increase in WWI was associated with a 36% increase in the risk of kidney stones. Dose–response curve analysis showed that WWI was non-linear correlated with the prevalence of kidney stone. In ROC analysis, WWI showed better discrimination for kidney stone (area under the curve: 0.612; 95% CI: 0.599–0.626; optimal cutoff value: 11.063) compared with other indices.

Conclusion

In this study, increased WWI was strongly associated with the risk of kidney stone.

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Data availability

The original contributions presented in the study are included in the article/Supplementary material; further inquiries can be directed to the corresponding author.

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Funding

This work was supported by the Guangdong Medical Research Foundation (A2020223 and A2021435) and Supporting Program of the First Affiliated Hospital of Shantou University Medical College (202003–3).

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Authors and Affiliations

  1. The First Affiliated Hospital of Shantou University Medical College, Medical College of Shantou University, Shantou, 515041, China

    Weilong Lin, Qianyi Ye & Ming-En Lin

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  1. Weilong Lin
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  2. Qianyi Ye
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  3. Ming-En Lin
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Contributions

WL: protocol/project development, data collection and management, data analysis, and manuscript writing; ML: protocol/project development and manuscript editing; QY: protocol/project development, data collection and management, data analysis, and manuscript writing.

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Correspondence to Ming-En Lin.

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Studies involving human participants are reviewed and approved by the NCHS Ethics Review Committee.

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Informed consent was obtained from all individual participants enrolled in the study.

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Lin, W., Ye, Q. & Lin, ME. Relationship between the weight-adjusted-waist index and kidney stone: a population-based study. World J Urol 41, 3141–3147 (2023). https://doi.org/10.1007/s00345-023-04620-8

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  • DOI: https://doi.org/10.1007/s00345-023-04620-8

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