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Evaluation of ultrathin semirigid ureteroscopy in terms of efficiency and cost compared to flexible ureteroscopy in treating proximal ureteric stones: a prospective randomized multicenter study

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Abstract

Purpose

To investigate the outcome and cost-effectiveness of ultrathin 6–7.5-Fr semirigid ureteroscopy in treating proximal ureteric stones compared to flexible ureteroscopy.

Methods

Two hundred and twenty patients with a solitary proximal ureteric stone were eligible for ureteroscopy (stone size = 1–2 cm). Patients were randomly subdivided into two groups: Group I included 105 patients who underwent ultrathin semirigid ureteroscopy and group II included 115 patients who underwent flexible ureteroscopy. Both groups were compared regarding successful stone access, operation time, reoperation rates, the financial cost to stone-free, complications, and stone clearance at 4 and 8 weeks.

Results

Groups I and II had no significant differences regarding patient demographics, stone criteria, and hospitalization time. In contrast, the mean operative time was significantly longer in group II (p < 0.001). The overall scope-to-stone access rate was 89.5%. It was 87.6% compared to 91.3% (p = 0.32), while the stone-free rate was 81.9% versus 87.8% (p = 0.22) for groups I and II, respectively. Intraoperative and postoperative complications were statistically insignificant between the study groups. The cost/person in Egyptian pounds was 8619 ± 350 in group I, compared to 17,620 ± 280 in group II (p < 0.001); similarly, the cost to attain the stone-free rate was 8950 ± 720 in group I compared to 17,950 ± 500 in group II.

Conclusion

Ultrathin semirigid ureteroscopy is safe, durable, and considered a cost-effective method for treating upper ureteric calculi compared to the flexible ureteroscopy and could be considered a first treatment option in developing countries.

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Availability of data and materials

Data sets used in this study are available upon reasonable request from the corresponding author.

Abbreviations

ESWL:

Extracorporeal shock wave lithotripsy

URS:

Ureteroscopy

F-URS:

Flexible ureteroscopy

KUB:

Kidney, ureter, and bladder

US:

Ultrasound

CTUT:

Computerized tomography of the urinary tract

LASER:

Light amplification by stimulated emission of radiation

MCCS:

Modified Clavien classification system

EGP:

Egyptian pounds

References

  1. Yuksel OH, Akan S, Urkmez A, Uruc F, Verit A (2015) Efficacy and safety of semirigid ureteroscopy combined with holmium: YAG laser in the treatment of upper urinary tract calculi: Is it a good alternative treatment option of flexible ureteroscopy for developing countries? J Pak Med Assoc 65(11):1193–1196

    PubMed  Google Scholar 

  2. Maislos SD, Volpe M, Albert PS et al (2004) Efficacy of the stone cone for treatment of proximal ureteral stones. J Endourol 18:862–864

    Article  CAS  PubMed  Google Scholar 

  3. Inoue T, Okada S, Hamamoto S, Fujisawa M (2021) Retrograde intrarenal surgery: Past, present, and future. Investig Clin Urol 62:121–135

    Article  PubMed  PubMed Central  Google Scholar 

  4. Perez Castro E, Osther PJ, Jinga V et al (2014) Differences in ureteroscopic stone treatment and outcomes for distal, mid-, proximal, or multiple ureteral locations: the Clinical Research Office of the Endourological Society ureteroscopy global study. Eur Urol 66:102–109

    Article  PubMed  Google Scholar 

  5. Khairy-Salem H, El-Ghonemi M, El-Atrebi M (2011) Semirigid ureteroscopy in management of large proximal ureteral calculi: is there still a role in developing countries? Urology 77:1064–1068

    Article  PubMed  Google Scholar 

  6. Ferretti S, Cuschera M, Campobasso D et al (2021) Rigid and flexible ureteroscopy (URS/RIRS) management of paediatric urolithiasis in a not endemic country. Arch Ital Urol Androl 93(1):26–30

    Article  PubMed  Google Scholar 

  7. Kotb YM, Mahmoud AF, Soliman KNH (2018) Comparative study between flexible ureteroscopy and semirigid ureteroscopy in management of upper ureteric stones using laser lithotripsy. Egypt J Hosp Med 018(73):5770–5776

    Article  Google Scholar 

  8. Lievore E, Zanetti SP, Fulgheri I et al (2022) Cost analysis between mini-percutaneous nephrolithotomy with and without vacuum-assisted access sheath. World J Urol 40(1):201–211

    Article  PubMed  Google Scholar 

  9. Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213

    Article  PubMed  PubMed Central  Google Scholar 

  10. Collins JW, Keeley FX, Timoney A (2004) Cost analysis of flexible ureterorenoscopy. BJU Int 93(7):1023–1026

    Article  CAS  PubMed  Google Scholar 

  11. Elashry OM, Tawfik AM (2012) Preventing stone retropulsion during intracorporeal lithotripsy. Nat Rev Urol 9(12):691–698

    Article  PubMed  Google Scholar 

  12. Afane JS, Olweny EO, Bercowsky E et al (2000) ureteroscopes: a single center evaluation of the durability and function of the new endoscopes smaller than 9Fr. J Urol 164:1164–1168

    Article  CAS  PubMed  Google Scholar 

  13. Atis G, Gurbuz C, Arikan O et al (2012) Ureteroscopic management with laser lithotripsy of renal pelvic Stones. J Endou Urol 26:983–987

    Google Scholar 

  14. Atis G, Arikan O, Gurbuz C et al (2013) Comparison of different ureteroscope sizes in treating ureteral calculi in adult patients. Urology 82:1231–1235

    Article  PubMed  Google Scholar 

  15. Kılınç MF, Doluoğlu ÖG, Karakan T et al (2016) The effect of ureteroscope size in the treatment of ureteral stone: 15-year experience of an endoscopist. Turk J Urol. 42(2):64–69

    Article  PubMed  PubMed Central  Google Scholar 

  16. Galal E, Ahmad Z, Tarek K et al (2016) Retrospective comparative study of rigid and flexible ureteroscopy for treatment of proximal ureteral stones. Int Braz J Urol 42(5):967–972

    Article  PubMed  PubMed Central  Google Scholar 

  17. Lai L, Zhang W, Zheng F et al (2021) Comparison of the efficacy of shuotong ureteroscopy and simple flexible ureteroscopy in the treatment of unilateral upper ureteral calculi. Front Surg 8:707022

    Article  PubMed  PubMed Central  Google Scholar 

  18. Abdullateef M, Shoma A, Sheir K et al (2016) A randomized controlled trial comparing flexible ureteroscopy, semirigid ureteroscopy (URS) and extracorporeal shockwaves lithotripsy (ESWL) for treatment of 0.5–1cm proximal ureteric stones. Eur Urol Suppl 15(3):e1132–e1132a

    Article  Google Scholar 

  19. Alkan E, Ali S, Ahmet O et al (2015) Flexible ureteroscopy can be more efficacious in the treatment of proximal ureteral stones in select patients. Adv Urol 20(2):70–73

    Google Scholar 

  20. Karadag M, Aslan D, Kursat C et al (2014) Flexible ureterorenoscopy versus semirigid ureteroscopy for the treatment of proximal ureteral stones: a retrospective comparative analysis of 124 patients. Urol J 11(5):1867–1872

    PubMed  Google Scholar 

  21. Turk C, Neisius A, Petrik A, et al (2022) EUA Guidelines on Urolithiasis. http://uroweb.org/wp-content/uploads/EUA-Guiedlines-on-Urolithiasis-2020.pdf. Accessed 26 Feb 2022

  22. Tipu S, Malik H, Mohhayuddin N et al (2007) Treatment of ureteric calculi–use of Holmium: YAG laser lithotripsy versus pneumatic lithoclast. J Pak Med Assoc 57:440–443

    PubMed  Google Scholar 

  23. Khan F, Tasleem A, Anjum F et al (2014) Complications of Holmium:YAG laser lithotripsy for upper tract calculi in 1000 consecutive procedures. Eur Urol Suppl 14(13):1028

    Article  Google Scholar 

  24. Jeon S, Hyun J, Lee K (2005) A comparison of holmium:YAG laser with Lithoclast lithotripsy in ureteral calculi fragmentation. Int J Urol 12:544–547

    Article  PubMed  Google Scholar 

  25. Mursi K, Elsheemy M, Morsi H et al (2013) Semirigid ureteroscopy for ureteric and renal pelvic calculi: predictive factors for complications and success. Arab J Urol 11:136–141

    Article  PubMed  PubMed Central  Google Scholar 

  26. Yencilek F, Kemal S, Tayfun G et al (2009) A comparison of shock wave lithotripsy, semirigid and flexible ureteroscopy in the management of proximal ureteral calculi/Proksimal üreter taslarinin tedavisinde sok dalga tedavisi, semirijid ve fleksibl üreteroskopinin karsilastirilmasi. Turk J Urol 35(2):101–107

    Google Scholar 

  27. Devarajan R, Ashraf M, Beck R et al (1998) Holmium: YAG lasertripsy for ureteric calculi: an experience of 300 procedures. Br J Urol 82:342–347

    Article  CAS  PubMed  Google Scholar 

  28. Ibrahim A (2015) Reporting ureteroscopy complications using the modified Clavien classification system. Urol Ann 7:53–57

    Article  PubMed  PubMed Central  Google Scholar 

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All listed authors (TMG, IA, AE, MF, OS and ASE) performed substantial contributions to conception and design, methodology, acquisition of data, or analysis, review, and interpretation of data.

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Correspondence to Ibrahim Abdel-Al.

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Gharib, T.M., Abdel-Al, I., Elatreisy, A. et al. Evaluation of ultrathin semirigid ureteroscopy in terms of efficiency and cost compared to flexible ureteroscopy in treating proximal ureteric stones: a prospective randomized multicenter study. World J Urol 41, 2527–2534 (2023). https://doi.org/10.1007/s00345-023-04507-8

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  • DOI: https://doi.org/10.1007/s00345-023-04507-8

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