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A robust enzymeless glucose sensor based on tin nickel sulfide nanocomposite modified electrodes

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Abstract

Tin-nickel sulfide nanocomposite deposited on nickel foam (TNS/NF) displays high electrocatalytic activity toward glucose oxidation. As an enzymeless glucose sensor, the TNS/NF sensing electrode shows a linear range of response from 3 to 5 mM, with a low detection limit of 0.18 μM signal-to-noise ratio of 3 and high sensitivity of 1622.9 μA mM−1 cm−2. In addition, the proposed sensing electrode shows a fast response time of less than 2 s on glucose addition. The resulting biosensor has high selectivity, excellent reproducibility, and long-term stability for glucose detection. It should be a worthy note; the TNS/NF could be successfully applied in determining glucose in a real blood sample at an applied voltage of 0.5 V.

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Acknowledgments

The authors are grateful to NIT Tiruchirappalli and MHRD for providing fellowship under the HTRA category. We are also thankful to SERB-DST under National Post-Doctoral Fellowship (SO. No: PDF/2019/001723) for financial support. The authors would like to acknowledge SAIF-IIT Madras for characterization studies.

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Authors and Affiliations

  1. Department of Chemical Engineering, Indian Institute of Technology Madras, Chennai, 600036, India

    Nivedhini Iswarya Chandrasekaran

  2. Applied and Industrial Microbiology Lab, Department of Biotechnology, Indian Institute of Technology Madras, Chennai, 600036, India

    M. Harshiny

  3. Department of Mechanical Engineering, National Creative Research Initiative for Functionally Antagonistic Nano-Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea

    Pitchai Thangasamy

  4. Department of Chemical Engineering, National Institute of Technology Tiruchirappalli, Tiruchirappalli, Tamil Nadu, 620015, India

    Manickam Matheswaran

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  1. Nivedhini Iswarya Chandrasekaran
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  2. M. Harshiny
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  4. Manickam Matheswaran
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Correspondence to Manickam Matheswaran.

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339_2020_4163_MOESM1_ESM.docx

Supporting information Description of material characterization, TEM micrographs, XPS survey spectrum with high-resolution spectra of Sn 3d, Ni 2p and S 2p spectrum, FTIR spectrum, and N2 sorption isotherm with pore size distribution curve of TNS nanostructure. Chronoamperometry response and a calibration curve of peak current vs. glucose concentration for a wide range of glucose concentration are provided in the supporting information.

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Chandrasekaran, N.I., Harshiny, M., Thangasamy, P. et al. A robust enzymeless glucose sensor based on tin nickel sulfide nanocomposite modified electrodes. Appl. Phys. A 127, 20 (2021). https://doi.org/10.1007/s00339-020-04163-4

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