Abstract
Purpose
To evaluate the characteristics of gallbladder polyps 10 mm or larger to predict a neoplasm in US examinations.
Materials and methods
Fifty-three patients with gallbladder polyps ≥ 10 mm with follow-up images or pathologic diagnosis were included in the retrospective study. All images and reports were reviewed to determine the imaging characteristics of gallbladder polyps. Univariate and multivariate analyses were used to evaluate predictors for a neoplastic polyp.
Results
A neoplastic polyp was verified in 12 of 53 patients and the mean size was 13.9 mm. The univariate analysis revealed that adjacent gallbladder wall thickening, larger size (≥15 mm), older age (≥57 years), absence of hyperechoic foci in a polyp, CT visibility, sessile shape, a solitary polyp, and an irregular surface were significant predictors for a neoplastic polyp. In the multivariate analysis, larger size (≥15 mm) was a significant predictor for a neoplastic polyp.
Conclusion
A polyp size ≥15 mm was the strongest predictor for a neoplastic polyp with US. The hyperechoic foci in a polyp and CT visibility would be useful indicators for the differentiation of a neoplastic polyp, in addition to the established predictors.
Key Points
• A polyp size ≥15 mm is the strongest predictor for a neoplastic polyp with US.
• Hyperechoic foci in a polyp and CT visibility are new predictors.
• The rate of malignancy is low in polyps even 10 mm or larger (15.1 %).
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Acknowledgements
The scientific guarantor of this publication is Jeong Kyong Lee. The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article. The authors state that this work has not received any funding. One of the authors has significant statistical expertise. Institutional Review Board approval was obtained. Written informed consent was waived by the Institutional Review Board. Study subjects or cohorts have not been previously reported. Methodology: retrospective, cross sectional study, performed at one institution.
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Kim, J.S., Lee, J.K., Kim, Y. et al. US characteristics for the prediction of neoplasm in gallbladder polyps 10 mm or larger. Eur Radiol 26, 1134–1140 (2016). https://doi.org/10.1007/s00330-015-3910-1
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DOI: https://doi.org/10.1007/s00330-015-3910-1