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Evaluation of the prevalence of musculoskeletal conditions in consecutive patients with skin psoriasis: a descriptive cross-sectional study

  • Observational Research
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Abstract

The association between psoriatic arthritis (PsA) and psoriasis is well known, but some have suggested that other musculoskeletal (MSK) conditions might also be more common in patients with skin psoriasis compared with the general population. The aim of our study was to describe the prevalence of a large panel of MSK conditions, in consecutive patients with psoriasis according to skin phenotype. This was a cross-sectional study. We consecutively included 148 patients, consulting for their skin psoriasis, in the dermatology department of a tertiary hospital, Hospital Cochin in Paris, France. After the scheduled consultation with a dermatologist, a rheumatologist conducted a dedicated face-to-face interview to collected data, included demographics, comorbidities, information about the psoriasis, the MSK conditions and their treatments. Of the 148 patients, 122 (82%) had at least one MSK condition. The most common condition was mechanical back pain, present in 98 (66%) patients. Nineteen (13%) patients had spondyloarthritis (SpA), of which 95% had PsA. For all MSK conditions, the dominant psoriasis phenotype was psoriasis vulgaris. The prevalence of the other phenotypes of psoriasis differed by disease. In SpA patients, the three predominant psoriasis phenotypes were: psoriasis vulgaris (82%), scalp involvement (76%) and inverse psoriasis (65%). For all MSK diseases, the prevalence was higher than expected in the general population. Our data suggest that skin psoriasis is associated with different MSK diseases, and not only PsA.

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All data pertaining to the study are included in the manuscript.

References

  1. Parisi R, Symmons DPM, Griffiths CEM et al (2013) Global epidemiology of psoriasis: a systematic review of incidence and prevalence. J Investig Dermatol 133:377–385. https://doi.org/10.1038/jid.2012.339

    Article  CAS  PubMed  Google Scholar 

  2. Alinaghi F, Calov M, Kristensen LE et al (2019) Prevalence of psoriatic arthritis in patients with psoriasis: a systematic review and meta-analysis of observational and clinical studies. J Am Acad Dermatol 80:251-265.e19. https://doi.org/10.1016/j.jaad.2018.06.027

    Article  PubMed  Google Scholar 

  3. van Romunde LK, Valkenburg HA, Swart-Bruinsma W et al (1984) Psoriasis and arthritis. I. A population study. Rheumatol Int 4:55–60

    Article  Google Scholar 

  4. Kathuria P, Gordon KB, Silverberg JI (2017) Association of psoriasis and psoriatic arthritis with osteoporosis and pathological fractures. J Am Acad Dermatol 76:1045-1053.e3. https://doi.org/10.1016/j.jaad.2016.11.046

    Article  PubMed  Google Scholar 

  5. Paskins Z, Whittle R, Abdul Sultan A et al (2018) Risk of fragility fracture among patients with late-onset psoriasis: a UK population-based study. Osteoporos Int J Establ Result Coop Eur Found Osteoporos Natl Osteoporos Found USA 29:1659–1664. https://doi.org/10.1007/s00198-018-4491-z

    Article  CAS  Google Scholar 

  6. Merola JF, Wu S, Han J et al (2015) Psoriasis, psoriatic arthritis and risk of gout in US men and women. Ann Rheum Dis 74:1495–1500. https://doi.org/10.1136/annrheumdis-2014-205212

    Article  PubMed  Google Scholar 

  7. De Marco G, Cattaneo A, Battafarano N et al (2012) Not simply a matter of psoriatic arthritis: epidemiology of rheumatic diseases in psoriatic patients. Arch Dermatol Res 304:719–726. https://doi.org/10.1007/s00403-012-1281-x

    Article  PubMed  Google Scholar 

  8. Hoy D, Bain C, Williams G et al (2012) A systematic review of the global prevalence of low back pain. Arthritis Rheumatol 64:2028–2037. https://doi.org/10.1002/art.34347

    Article  Google Scholar 

  9. Birtwhistle R, Morkem R, Peat G et al (2015) Prevalence and management of osteoarthritis in primary care: an epidemiologic cohort study from the Canadian Primary Care Sentinel Surveillance Network. CMAJ Open 3:E270-275. https://doi.org/10.9778/cmajo.20150018

    Article  PubMed  PubMed Central  Google Scholar 

  10. Hopkins C, Fu S-C, Chua E et al (2016) Critical review on the socio-economic impact of tendinopathy. Asia Pac J Sports Med Arthrosc Rehabil Technol 4:9–20. https://doi.org/10.1016/j.asmart.2016.01.002

    Article  PubMed  PubMed Central  Google Scholar 

  11. Lewinson RT, Vallerand IA, Parsons LM et al (2018) Psoriasis and the risk of foot and ankle tendinopathy or enthesopathy in the absence of psoriatic arthritis: a population-based study. RMD Open 4:e000668. https://doi.org/10.1136/rmdopen-2018-000668

    Article  PubMed  PubMed Central  Google Scholar 

  12. Scotti L, Franchi M, Marchesoni A, Corrao G (2018) Prevalence and incidence of psoriatic arthritis: a systematic review and meta-analysis. Semin Arthritis Rheum 48:28–34. https://doi.org/10.1016/j.semarthrit.2018.01.003

    Article  PubMed  Google Scholar 

  13. Taylor W, Gladman D, Helliwell P et al (2006) Classification criteria for psoriatic arthritis: development of new criteria from a large international study. Arthritis Rheumatol 54:2665–2673. https://doi.org/10.1002/art.21972

    Article  Google Scholar 

  14. Gladman DD, Antoni C, Mease P et al (2005) Psoriatic arthritis: epidemiology, clinical features, course, and outcome. Ann Rheumatol Dis 64(Suppl 2):14–17. https://doi.org/10.1136/ard.2004.032482

    Article  Google Scholar 

  15. Prey S, Paul C, Bronsard V et al (2010) Assessment of risk of psoriatic arthritis in patients with plaque psoriasis: a systematic review of the literature. J Eur Acad Dermatol Venereol JEADV 24(Suppl 2):31–35. https://doi.org/10.1111/j.1468-3083.2009.03565.x

    Article  PubMed  Google Scholar 

  16. Nakamura M, Abrouk M, Zhu H et al (2017) Update on the systemic risks of superpotent topical steroids. J Drugs Dermatol 16:643–648

    PubMed  Google Scholar 

  17. Melton LJ (1995) How many women have osteoporosis now? J Bone Miner Res 10:175–177. https://doi.org/10.1002/jbmr.5650100202

    Article  PubMed  Google Scholar 

  18. Johnell O, Kanis J (2005) Epidemiology of osteoporotic fractures. Osteoporos Int J Establ Result Coop Eur Found Osteoporos Natl Osteoporos Found USA 16(Suppl 2):S3-7. https://doi.org/10.1007/s00198-004-1702-6

    Article  Google Scholar 

  19. Lespessailles E, Cotté F-E, Roux C et al (2009) Prevalence and features of osteoporosis in the French general population: the Instant study. Jt Bone Spine 76:394–400. https://doi.org/10.1016/j.jbspin.2008.10.008

    Article  Google Scholar 

  20. Saag KG, Choi H (2006) Epidemiology, risk factors, and lifestyle modifications for gout. Arthritis Res Ther 8(Suppl 1):S2. https://doi.org/10.1186/ar1907

    Article  PubMed  PubMed Central  Google Scholar 

  21. Thorarensen SM, Lu N, Ogdie A et al (2017) Physical trauma recorded in primary care is associated with the onset of psoriatic arthritis among patients with psoriasis. Ann Rheum Dis 76:521–525. https://doi.org/10.1136/annrheumdis-2016-209334

    Article  PubMed  Google Scholar 

  22. McGonagle D, Lories RJU, Tan AL, Benjamin M (2007) The concept of a “synovio-entheseal complex” and its implications for understanding joint inflammation and damage in psoriatic arthritis and beyond. Arthritis Rheumatol 56:2482–2491. https://doi.org/10.1002/art.22758

    Article  Google Scholar 

  23. Gladman DD (2015) Clinical features and diagnostic considerations in psoriatic arthritis. Rheum Dis Clin N Am 41:569–579. https://doi.org/10.1016/j.rdc.2015.07.003

    Article  Google Scholar 

  24. Roure F, Elhai M, Burki V et al (2016) Prevalence and clinical characteristics of psoriasis in spondyloarthritis: a descriptive analysis of 275 patients. Clin Exp Rheumatol 34:82–87

    PubMed  Google Scholar 

  25. Wilson FC, Icen M, Crowson CS et al (2009) Incidence and clinical predictors of psoriatic arthritis in patients with psoriasis: a population-based study. Arthritis Rheumatol 61:233–239. https://doi.org/10.1002/art.24172

    Article  CAS  Google Scholar 

  26. Shin D, Kim HJ, Kim DS et al (2016) Clinical features of psoriatic arthritis in Korean patients with psoriasis: a cross-sectional observational study of 196 patients with psoriasis using psoriatic arthritis screening questionnaires. Rheumatol Int 36:207–212. https://doi.org/10.1007/s00296-015-3365-3

    Article  PubMed  Google Scholar 

  27. Molin L (1973) Psoriasis. A study of the course and degree of severity, joint involvement, socio-medical conditions, general morbidity and influences of selection factors among previously hospitalized psoriatics. Acta Dermato Venereol Suppl (Stockh) 53:1–125. https://doi.org/10.2340/00015555721125

    Article  CAS  Google Scholar 

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Funding

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

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Authors and Affiliations

  1. Rheumatology Department, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, 27 rue du Faubourg Saint-Jacques, 75014, Paris, France

    Astrid Dauchez, Maxime Dougados & Anna Moltó

  2. INSERM U-1153, CRESS Sorbonne Paris Cité-Université de Paris, Paris, France

    Maxime Dougados & Anna Moltó

  3. Dermatology Department, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France

    Mathilde Kemula, Elodie Regnier & Selim Aractingi

Authors
  1. Astrid Dauchez
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  2. Maxime Dougados
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  3. Mathilde Kemula
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  4. Elodie Regnier
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  5. Selim Aractingi
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  6. Anna Moltó
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Contributions

MD, SA, AM and AD contributed to the study conception and design. Material preparation, data collection and analysis were performed by AD and supervised by AM. The first draft of the manuscript was written by AD. All authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

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Correspondence to Astrid Dauchez.

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The authors have no conflict of interest to declare.

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The informed consent of all patients has been obtained to participate in the study.

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Dauchez, A., Dougados, M., Kemula, M. et al. Evaluation of the prevalence of musculoskeletal conditions in consecutive patients with skin psoriasis: a descriptive cross-sectional study. Rheumatol Int 42, 651–657 (2022). https://doi.org/10.1007/s00296-022-05099-z

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  • DOI: https://doi.org/10.1007/s00296-022-05099-z

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