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Ultrasonographic assessment of femoral cartilage thickness in patients with and without uveitis in Behçet’s disease

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Abstract

The objective for this study is to evaluate the femoral cartilage thickness in patients with/without uveitis in Behçet’s disease (BD). Patients with BD aged 18–70 years were included. The demographic and clinical characteristics of the patients were recorded. The thickness of femoral articular cartilage was measured with musculoskeletal ultrasound. Cartilage thickness was measured bilaterally from the central points of medial condyle (MFC), lateral condyle (LFC), and intercondylar area (ICA). 20 patients with uveitis [uveitis (+)] and 20 patients without uveitis [uveitis (−)] were included. Both right and left MFC and LFC had statistically significant thinner cartilage in uveitis (+) group (p < 0.05). For the ICA, uveitis (+) patients had thinner femoral cartilage than uveitis (−) patients; however, in the left side, statistically significance could not be detected. Femoral cartilage was thinner in uveitis (+) patients than in uveitis (−) patients in BD. This relationship between uveitis and femoral cartilage thickness may be helpful in the prevention and early treatment of cartilage degeneration.

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Acknowledgements

We would like to express our special thanks to Eyüp DÜZGÜN MD for his contribution to the study.

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There has been no significant financial support for this work that could have influenced its outcome.

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Correspondence to Tugba Ozsoy-Unubol.

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All procedures performed in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The study was approved by local ethic committee of İstanbul Haydarpaşa Numune Training and Research Hospital (11.05.2015/HNEAH-KAEK 2015/41). The manuscript has three authors and each author is responsible for the content and writing of the paper.

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Ata, E., Kosem, M. & Ozsoy-Unubol, T. Ultrasonographic assessment of femoral cartilage thickness in patients with and without uveitis in Behçet’s disease. Rheumatol Int 40, 75–80 (2020). https://doi.org/10.1007/s00296-019-04361-1

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