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Prevalence and risk factors of anxiety and depression in patients with systemic lupus erythematosus in Southwest China

  • Observational Research
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Abstract

Systemic lupus erythematosus (SLE) patients have high risk for anxiety and depression. We aimed to investigate the prevalence and risk factors of anxiety and depression in SLE patients in Southwest China. Participants were recruited by convenience sampling from Rheumatic Outpatient Clinic of West China Hospital Sichuan University between August and October 2014. The prevalence of anxiety and depression was evaluated using Hospital Anxiety and Depression Scale (HADS). Risk factors were explored by multiple logistic regression analyses. A total of 352 participants were enrolled, of who 64 (18.2 %) met the HADS criteria for anxiety and 82 (23.3 %) for depression. In multivariable analysis, higher levels of pain (OR = 1.17, P = 0.02) and fatigue (OR = 1.19, P < 0.01) predicted a higher risk of anxiety. Similarly, a higher level of fatigue (OR = 1.2, P < 0.01) was associated with a higher risk of depression. The results suggest that anxiety and depression are common in patients with SLE in Southwest China. Health care providers and SLE patients should take some measures to cope with them as early as possible. Strengthening management of pain and fatigue may be useful. But further studies are needed to verify these findings.

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Acknowledgments

We would like to thank all patients for sincerely finishing our investigation and staffs at Rheumatic Outpatient Clinic of West China Hospital Sichuan University for providing continued support.

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Authors and Affiliations

  1. West China School of Nursing and Department of Nursing, West China Hospital, Sichuan University, Chengdu, China

    Xia Xie & Hong Chen

  2. Pain Management Ward of West China Hospital, Sichuan University, Chengdu, China

    Dongmei Wu

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  1. Xia Xie
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  2. Dongmei Wu
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  3. Hong Chen
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Correspondence to Hong Chen.

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Xia Xie, Dongmei Wu and Hong Chen declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Xie, X., Wu, D. & Chen, H. Prevalence and risk factors of anxiety and depression in patients with systemic lupus erythematosus in Southwest China. Rheumatol Int 36, 1705–1710 (2016). https://doi.org/10.1007/s00296-016-3559-3

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  • DOI: https://doi.org/10.1007/s00296-016-3559-3

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