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Algae-Mediated Removal of Prevalent Genotoxic Antibiotics: Molecular Perspective on Algae-Bacteria Consortia and Bioreactor-Based Strategies

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Abstract

Antibiotic pollution poses a potential risk of genotoxicity, as antibiotics released into the environment can induce DNA damage and mutagenesis in various organisms. This pollution, stemming from pharmaceutical manufacturing, agriculture, and improper disposal, can disrupt aquatic ecosystems and potentially impact human health through the consumption of contaminated water and food. The removal of genotoxic antibiotics using algae-mediated approaches has gained considerable attention due to its potential for mitigating the environmental and health risks associated with these compounds. The paper provides an in-depth examination of the molecular aspects concerning algae and bioreactor-driven methodologies utilized for the elimination of deleterious antibiotics. The molecular analysis encompasses diverse facets, encompassing the discernment and profiling of algae species proficient in antibiotic degradation, the explication of enzymatic degradation pathways, and the refinement of bioreactor configurations to augment removal efficacy. Emphasizing the significance of investigating algal approaches for mitigating antibiotic pollution, this paper underscores their potential as a sustainable solution, safeguarding both the environment and human health.

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Authors and Affiliations

  1. School of Bioengineering and Biosciences, Lovely Professional University, Jalandhar, Punjab, 144411, India

    Atif Khurshid Wani, Tahir ul Gani Mir, Nahid Akhtar, Chirag Chopra & Reena Singh

  2. Biochemistry & Molecular Biology Lab, Division of Veterinary Biochemistry, Faculty of Veterinary Sciences and Animal Husbandry, Sher-e-Kashmir University of Agricultural Sciences and Technology, Srinagar, Jammu and Kashmir, 190006, India

    Showkeen Muzamil Bashir

  3. Department of Biology, College of Arts and Sciences, Khalifa University, Main Campus, Abu Dhabi, United Arab Emirates

    Shabir Hassan

  4. Department of Microbiology, School of Life Sciences, Central University of Rajasthan, NH-8, Bandarsindri, Kishangarh, Ajmer, Rajasthan, 305817, India

    Vineet Kumar

  5. Department of Forest Science, Soils and Environment, School of Agronomic Sciences, São Paulo State University (UNESP), Ave. Universitária, 3780, Botucatu, São Paulo, 18610-034, Brazil

    Juliana Heloisa Pinê Américo-Pinheiro

  6. Brazil University, Street Carolina Fonseca, 584, São Paulo, São Paulo, 08230-030, Brazil

    Juliana Heloisa Pinê Américo-Pinheiro

Authors
  1. Atif Khurshid Wani
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  2. Tahir ul Gani Mir
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  3. Nahid Akhtar
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  7. Vineet Kumar
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  8. Reena Singh
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  9. Juliana Heloisa Pinê Américo-Pinheiro
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Contributions

AKW: Conceptualization; Data curation; Formal analysis; Investigation; Methodology; Resources; Software; Validation; Visualization; Roles/Writing—original draft; Writing—review and editing. TGM, NA, CC: Conceptualization; Validation; Visualization; Roles/Writing—original draft. SMB, SH: Visualization; Roles/Writing—original draft. VK: Visualization, Reviewing and Editing. RS: Investigation; Methodology; Resources; Software; Validation; Visualization; Roles/Writing—original draft; Supervision. JHPAP: Formal analysis, Software, Resources, Writing—original draft, Administration, Supervision, Submission, Reviewing and Editing.

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Correspondence to Juliana Heloisa Pinê Américo-Pinheiro.

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Wani, A.K., ul Gani Mir, T., Akhtar, N. et al. Algae-Mediated Removal of Prevalent Genotoxic Antibiotics: Molecular Perspective on Algae-Bacteria Consortia and Bioreactor-Based Strategies. Curr Microbiol 81, 112 (2024). https://doi.org/10.1007/s00284-024-03631-x

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