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Application of Percutaneous Osteoplasty in Treating Pelvic Bone Metastases: Efficacy and Safety

  • Clinical Investigation
  • Non-Vascular Interventions
  • Published:
CardioVascular and Interventional Radiology Aims and scope Submit manuscript

Abstract

Background

Percutaneous vertebroplasty has been a good option to treat vertebral metastases. The pelvic bone is a common site of spread for many cancers. Using follow-up data for 126 patients, we evaluated the safety and efficacy of percutaneous osteoplasty (POP) to treat pelvic bone metastases.

Materials and Methods

In this retrospective study, 126 patients (mean age 57.45 ± 11.46 years old) with 178 lesions were treated using POP. The visual analog scale (VAS), Oswestry Disability Index (ODI), and the changes in the patient’s use of painkillers were used to evaluate pain and quality of life before the procedure, and at 3 days and 1, 3, 6, 9, and 12 months after the procedure.

Results

Technical success was achieved in all patients. The mean VAS scores decreased significantly from 6.87 ± 1.33 before the procedure to 3.33 ± 1.94 by day 3 after the procedure (P < 0.05), 2.26 ± 1.59 at 1 month (P < 0.05), 1.89 ± 1.53 at 3 months (P < 0.05), 1.87 ± 1.46 at 6 months (P < 0.05), 1.90 ± 1.47 at 9 months (P < 0.05), and 1.49 ± 1.17 at 12 months (P < 0.05). The ODI also changed after the procedure, with significant differences between baseline scores and at each follow-up examination (P < 0.05). Pain relief was achieved in 118 patients (93.65%); however, pain relief was not obvious in seven patients (5.56%), and pain was aggravated in one patient (0.79%). Extraosseous cement leakage occurred in 35 patients (27.78%) without causing any clinical complications.

Conclusion

Percutaneous osteoplasty is a safe and effective choice for patients with painful osteolytic pelvic bone metastases. It can relieve pain, reduce disability, and improve function.

Level of Evidence

Level 3b, retrospective study.

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Acknowledgements

This work was sponsored by grant Natural Fund from Shanghai Science and Technology Commission (Grant numbers 18ZR1429400, 19411971800), China.

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Authors and Affiliations

  1. Department of Diagnostic and Interventional Radiology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, No. 600 Yishan Road, Shanghai, 200233, China

    He-Fei Liu, Chun-Gen Wu, Qing-Hua Tian, Tao Wang & Fei Yi

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  1. He-Fei Liu
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  2. Chun-Gen Wu
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  3. Qing-Hua Tian
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  4. Tao Wang
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Correspondence to Chun-Gen Wu.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Liu, HF., Wu, CG., Tian, QH. et al. Application of Percutaneous Osteoplasty in Treating Pelvic Bone Metastases: Efficacy and Safety. Cardiovasc Intervent Radiol 42, 1738–1744 (2019). https://doi.org/10.1007/s00270-019-02320-8

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