Skip to main content

Advertisement

SpringerLink
Log in

Multimodality Imaging Approach towards Primary Aortic Sarcomas Arising after Endovascular Abdominal Aortic Aneurysm Repair: Case Series Report

  • Case Report
  • Published:
CardioVascular and Interventional Radiology Aims and scope Submit manuscript

Abstract

Primary aortic neoplasms are rare. Aortic sarcoma arising after endovascular aneurysm repair (EVAR) is a scarce subset of primary aortic malignancies, reports of which are infrequent in the published literature. The diagnosis of aortic sarcoma is challenging due to its non-specific clinical presentation, and the prognosis is poor due to delayed diagnosis, rapid proliferation, and propensity for metastasis. Post-EVAR, aortic sarcomas may mimic other more common aortic processes on surveillance imaging. Radiologists are rarely knowledgeable about this rare entity for which multimodality imaging and awareness are invaluable in early diagnosis. A series of three pathologically confirmed cases are presented to display the multimodality imaging features and clinical presentations of aortic sarcoma arising after EVAR.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8

Similar content being viewed by others

References

  1. Seelig MH, Klingler PJ, Oldenburg WA, Blackshear JL. Angiosarcoma of the aorta: report of a case and review of the literature. J Vasc Surg. 1998;28:732–7.

    Article  CAS  PubMed  Google Scholar 

  2. Schmehl J, Scharpf M, Brechtel K, Kalender G, Heller S, Claussen CD, Lescan M. Epithelioid angiosarcoma with metastatic disease after endovascular therapy of abdominal aortic aneurysm. Cardiovasc Interv Radiol. 2012;35:190–3.

    Article  Google Scholar 

  3. Fenton J, Veenstra M, Bove P. Angiosarcoma involving native abdominal aortic aneurysm sac after endograft repair. Ann Vasc Surg. 2014;28(490):e1–4.

    PubMed  Google Scholar 

  4. Malone MD, Kerr K, Kavanah M, Menzoian JO. Primary leiomyosarcoma of the abdominal aorta. J Vasc Surg. 1996;24:487–93.

    Article  CAS  PubMed  Google Scholar 

  5. Wright EP, Glick AD, Virmani R, Page DL. Aortic intimal sarcoma with embolic metastases. Am J Surg Pathol. 1985;9:890–7.

    Article  CAS  PubMed  Google Scholar 

  6. Alexander JJ, Moawad J, Cai D. Primary intimal sarcoma of the aorta associated with a dacron graft and resulting in arterial rupture. Vasc Endovasc Surg. 2006;40:509–15.

    Article  Google Scholar 

  7. Ben-Izhak O, Vlodavsky E, Ofer A, Engel A, Nitecky S, Hoffman A. Epithelioid angiosarcoma associated with a Dacron vascular graft. Am J Surg Pathol. 1999;23:1418–22.

    Article  CAS  PubMed  Google Scholar 

  8. Fatima J, Duncan AA, Maleszewski JJ, Kalra M, Oderich GS, Gloviczki P, Suri RM, Bower TC. Primary angiosarcoma of the aorta, great vessels, and the heart. J Vasc Surg. 2013;57:756–64.

    Article  PubMed  Google Scholar 

  9. Nakajima H, Kobayashi J, Matsuda H, Ishibashi-Ueda H. A primary angiosarcoma in the aorta. Interact Cardiovasc Thorac Surg. 2007;6:832–3.

    Article  PubMed  Google Scholar 

  10. Brand KG. Diversity and complexity of carcinogenic processes: conceptual inferences from foreign-body tumorigenesis. J Natl Cancer Inst. 1976;57:973–6.

    CAS  PubMed  Google Scholar 

  11. Oppenheimer BS, Oppenheimer ET, Stout AP, Willhite M, Danishefsky I. The latent period in carcinogenesis by plastics in rats and its relation to the presarcomatous stage. Cancer. 1958;11:204–13.

    Article  CAS  PubMed  Google Scholar 

  12. Onuma K, Sato Y, Ogawara S, Shirasawa N, Kobayashi M, Yoshitake J, Yoshimura T, Iigo M, Fujii J, Okada F. Nano-scaled particles of titanium dioxide convert benign mouse fibrosarcoma cells into aggressive tumor cells. Am J Pathol. 2009;175:2171–83.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Hansen T, Clermont G, Alves A, Eloy R, Brochhausen C, Boutrand JP, Gatti AM, Kirkpatrick CJ. Biological tolerance of different materials in bulk and nanoparticulate form in a rat model: sarcoma development by nanoparticles. J R Soc Interface. 2006;3:767–75.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Garg N, Lewis MA, Maleszewski JJ, Kalra M. Intimal sarcoma in an inflammatory aneurysm after endovascular aneurysm repair. J Vasc Surg. 2012;55:1134–7.

    Article  PubMed  Google Scholar 

  15. Umscheid TW, Rouhani G, Morlang T, Lorey T, Klein P-J, Ziegler P, Stelter WJ. Hemangiosarcoma after endovascular aortic aneurysm repair. J Endovasc Ther. 2007;14:101–5.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 South Kingshighway Boulevard, St Louis, MO, 63110, USA

    Mudassar Kamran, Kathryn J. Fowler, Vincent M. Mellnick & Vamsi R. Narra

  2. Department of Surgery, Washington University School of Medicine, St Louis, MO, USA

    Gregorio A. Sicard

Authors
  1. Mudassar Kamran
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Kathryn J. Fowler
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Vincent M. Mellnick
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Gregorio A. Sicard
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Vamsi R. Narra
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Mudassar Kamran.

Ethics declarations

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

For this type of study formal consent is not required.

Informed Consent

Does not apply.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kamran, M., Fowler, K.J., Mellnick, V.M. et al. Multimodality Imaging Approach towards Primary Aortic Sarcomas Arising after Endovascular Abdominal Aortic Aneurysm Repair: Case Series Report. Cardiovasc Intervent Radiol 39, 940–947 (2016). https://doi.org/10.1007/s00270-015-1280-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00270-015-1280-3

Keywords

Search

Navigation