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Massive Cerebral Infarction Following Facial Fat Injection

  • Case Report
  • Experimental/Special Topics
  • Published:
Aesthetic Plastic Surgery Aims and scope Submit manuscript

Abstract

Background

Autologous facial fat injection is becoming popular around the world. Semiliquid fat grafts are used for correction of deformities or aesthetic purposes. Fat transfer is a mini-invasive surgical procedure, but causes severe complications occasionally.

Methods

A 30-year-old female patient presented to our hospital with sudden unconsciousness and left limb weakness 8 h after facial fat injection. Brain arteriography (CTA) and venography were performed immediately after her admission. Frontal temporoparietal decompressive craniectomy plus multiple treatments was scheduled for the patient.

Results

The patient was diagnosed with extensive cerebral infarction of the right hemisphere. CTA showed that both external and internal carotid arteries were obstructed. A sectional filling defect could be seen at the telecentric segment of the right carotid artery. No development was observed during the full course of the treatment at the carotid bifurcation, external carotid artery, or internal carotid artery.

Conclusion

Routine cosmetic procedures of facial fat injections could cause devastating and even fatal complications to patients.

Level of Evidence V

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the A5 online Instructions to Authors www.springer.com/00266

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References

  1. Lee YJ, Kim HJ, Choi KD, Choi HY (2010) MRI restricted diffusion in optic nerve infarction after autologous fat transplantation. J Neuro-Ophthalmol 30:216–218

    Article  Google Scholar 

  2. Park SH, Sun HJ, Choi KS (2008) Sudden unilateral visual loss after autologous fat injection into the nasolabial fold. Clin Ophthalmol 2:679–683

    PubMed  PubMed Central  Google Scholar 

  3. Beretta L, Calvi, Frascoli C, Anzalone N (2008) Cerebral fat embolism, brain swelling, and severe intracranial hypertension. J Trauma 65(5):E46–E48

    Article  PubMed  Google Scholar 

  4. Egido JA, Arroyo R, Marcos A, Jiménez-Alfaro I (1993) Middle cerebral artery embolism and unilateral visual loss after autologous fat injection into the glabellar area. Stroke 24:615–616

    Article  CAS  PubMed  Google Scholar 

  5. Han SJ, Kim JS, Chung SR (2006) Cerebral and ocular fat embolism after autologous fat injection into the face: confirmed by magnetic resonance spectroscopy. J Kor Neurol Assoc 24:399–401

    Google Scholar 

  6. Thaunat O, Thaler F, Loirat P, Decroix JP, Boulin A (2004) Cerebral fat embolism induced by facial fat injection. Plast Reconstr Surg 7:2235–2236

    Article  Google Scholar 

  7. Wang DW, Yin YM, Yao YM (2014) Internal and external carotid artery embolism following facial injection of autologous fat. Aesthet Surg J 34(8):NP83–NP87

    Article  PubMed  Google Scholar 

  8. Park SH, Sun HJ, Choi KS (2008) Sudden unilateral visual loss after autologous fat injection into the nasolabial fold. Clin Ophthalmol 2:679–683

    PubMed  PubMed Central  Google Scholar 

  9. Danesh Meyer HV, Savino PJ, Sergott RC (2001) Case reports and small case series: ocular and cerebral ischemia following facial injection of autologous fat. Arch Ophthalmol 119:777–778

    CAS  PubMed  Google Scholar 

  10. Akhtar S (2009) Fat embolism. Anesthesiol Clin 27:533–550

    Article  PubMed  Google Scholar 

  11. Guillevin R, Vallée JN, Demeret S (2005) Cerebral fat embolism: usefulness of magnetic resonance spectroscopy. Ann Neurol 57:434–439

    Article  PubMed  Google Scholar 

  12. Robinson EF, Soloway HB (1971) Experimental cerebral fat embolism. Distribution of radioactive triolein following internal carotid introduction. Arch Neurol 24:419–422

    Article  CAS  PubMed  Google Scholar 

  13. Kamenar E, Burger PC (1980) Cerebral fat embolism: a neuropathological study of a microembolic state. Stroke 11:477–484

    Article  CAS  PubMed  Google Scholar 

  14. Thicoipe M, Andre M, Maurette P et al (1998) Post-traumatic cerebral fat embolism. Ann Fr Anesth Reanim 7:418–421

    Article  Google Scholar 

  15. Glaich AS, Cohen JL, Goldberg LH (2006) Injection necrosis of the glabella: protocol for prevention and treatment after use of dermal fillers. Dermatol Surg 32:276–281

    CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Plastic and Burn Surgery, The First Affiliated Hospital of Chongqing Medical University, No. 1 You Yi Road, Chongqing, China

    Xiao Shen & Hengshu Zhang

  2. Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

    Qi Li

Authors
  1. Xiao Shen
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  2. Qi Li
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  3. Hengshu Zhang
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Corresponding author

Correspondence to Hengshu Zhang.

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The authors have no conflict of interest to declare.

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Shen, X., Li, Q. & Zhang, H. Massive Cerebral Infarction Following Facial Fat Injection. Aesth Plast Surg 40, 801–805 (2016). https://doi.org/10.1007/s00266-016-0681-2

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  • DOI: https://doi.org/10.1007/s00266-016-0681-2

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