Skip to main content
Log in

Pyogenic lumbar spondylodiscitis treated with transforaminal lumbar interbody fusion: safety and outcomes

  • Original Paper
  • Published:
International Orthopaedics Aims and scope Submit manuscript

Abstract

Purpose

Our aim was to study the safety and outcomes of posterior instrumentation and transforaminal lumbar interbody fusion (TLIF) for treating pyogenic lumbar spondylodiscitis.

Methods

Retrospective analysis was performed on prospectively collected data of 27 consecutive cases of lumbar pyogenic spondylodiscitis treated with posterior instrumentation and TLIF between January 2009 and December 2012. Cases were analysed for safety, radiological and clinical outcomes of transforaminal interbody fusion using bone graft ± titanium cages. Interbody metallic cages with bone graft were used in 17 cases and ten cases used only bone graft. Indications for surgical treatment were failed conservative management in 17, neurodeficit in six and significant bony destruction in four.

Results

There were no cases reporting cage migration, loosening, pseudoarthrosis or recurrence of infection at a mean follow-up of 30 months. Clinical outcomes were assessed using Kirkaldy–Willis criteria, which showed 14 excellent, nine good, three fair and one poor result. Mean focal deformity improved with the use of bone graft ± interbody cages, and the deformity correction was maintained at final follow-up. Mean pre-operative focal lordosis for the graft group was 8.5° (2–16.5°), which improved to 10.9 °(3.3–16°); mean pre-operative focal lordosis in the group treated with cages was 6.7 °(0–15°), which improved to 7°(0–15°) .

Conclusion

TLIFs with cages in patients with pyogenic lumbar spondylodiscitis allows for acceptable clearance of infection, satisfactory deformity correction with low incidence of cage migration, loosening and infection recurrence.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. An KC, Kim JY, Kim TH, Kim JS, Park DH, Kim JG, Sung TW (2012) Posterior lumbar interbody fusion using compressive bone graft with allograft and autograft in the pyogenic discitis. Asian, Spine J 6(1):15–21

    Article  Google Scholar 

  2. Nasto LA, Colangelo D, Mazzotta V, Di Meco E, Neri V, Nasto RA, Pola E (2013) Is posterior percutaneous screw-rod instrumentation a safe and effective alternative approach to TLSO rigid bracing for single-level pyogenic spondylodiscitis? Results of a retrospective cohort analysis. Spine J 14(7):1139–1146

    Article  PubMed  Google Scholar 

  3. Cheung WY, Luk KD (2012) Pyogenic spondylitis. Int Orthop 36(2):397–404

    Article  CAS  PubMed  Google Scholar 

  4. Kapsalaki E, Gatselis N, Stefos A, Makaritsis K, Vassiou A, Fezoulidis I, Dalekos GN (2009) Spontaneous spondylodiscitis: presentation, risk factors, diagnosis, management, and outcome. Int J Infect Dis 13(5):564–569

    Article  PubMed  Google Scholar 

  5. Adam D, Papacocea T, Hornea I, Croitoru R (2014) Postoperative spondylodiscitis. A review of 24 consecutive patients. Chirurgia 109:90–94

    CAS  PubMed  Google Scholar 

  6. Moon M S, Kim S S, Lee B J, Moon J L, Sihn J C, & Moon S I (2012). Pyogenic discitis following discectomy. J Orthop Surg 20(1)

  7. Guerado E, Cerván AM (2012) Surgical treatment of spondylodiscitis. An update. Int Orthop 36(2):413–420

    Article  PubMed  PubMed Central  Google Scholar 

  8. Zarghooni K, Röllinghoff M, Sobottke R, Eysel P (2012) Treatment of spondylodiscitis. Int Orthop 36(2):405–411

    Article  PubMed  Google Scholar 

  9. Lee JS, Suh KT (2006) Posterior lumbar interbody fusion with an autogenous iliac crest bone graft in the treatment of pyogenic spondylodiscitis. J Bone Joint Surg Bri Vol 88(6):765–770

    Article  CAS  Google Scholar 

  10. Lin CP, Ma HL, Wang ST, Liu CL, Yu WK, Chang MC (2012) Surgical results of long posterior fixation with short fusion for treating pyogenic spondylodiscitis of the thoracic and lumbar spine: a retrospective study. Spine 37(25):E1572–E1579

    Article  PubMed  Google Scholar 

  11. Jain AK, Aggarwal A, Dhammi IK, Aggarwal PK, Singh S (2004) Extrapleural anterolateral decompression in tuberculosis of the dorsal spine. J Bone Joint Surg (Br) 86-B:1027–1031

    Article  Google Scholar 

  12. Moon MS, Woo YK, Lee KS et al (1995) Posterior instrumentation and anterior interbody fusion for tuberculous kyphosis of dorsal and lumbar spines. Spine 20:1910–1916

    Article  CAS  PubMed  Google Scholar 

  13. Garg B, Kandwal P, Upendra BN, Goswami A, Jayswal A (2012) Anterior versus posterior procedure for surgical treatment of Thoracolumbar tuberculosis: a retrospective analysis. Ind J Orthop 46:165–170

    Article  Google Scholar 

  14. Sundararaj GD, Amritanand R, Venkatesh K, Arockiaraj J (2011) The use of titanium mesh cages in the reconstruction of anterior column defects in active spinal infections: can we rest the crest? Asian Spine J 5(3):155–161

    Article  PubMed  PubMed Central  Google Scholar 

  15. Hee HT, Majd ME, Holt RT, Pienkowski D (2002) Better treatment of vertebral osteomyelitis using posterior stabilization and titanium mesh cages. J Spinal Disord Tech 15:149–156

    Article  PubMed  Google Scholar 

  16. Liljenqvist U, Lerner T, Bullmann V, Hackenberg L, Halm H, Winkelmann W (2003) Titanium cages in the surgical treatment of severe vertebral osteomyelitis. Eur Spine J 12:606–612

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Frankel HL, Hancock DO, Hyslop G et al (1969) The value of postural reduction in the initial management of the closed injuries of the spine with paraplegia and tetraplegia. Paraplegia 7:179–192

    Article  CAS  PubMed  Google Scholar 

  18. Kirkaldy-Willis WH, Paine KW, Cauchoix J et al (1974) Lumbar spinal stenosis. Clin Orthop 99:30–50

    Article  PubMed  Google Scholar 

  19. Deininger MH, Unfried MI, Vougioukas VI, Hubbe U (2009) Minimally invasive dorsal percutaneous spondylodesis for the treatment of adult pyogenic spondylodiscitis. Acta Neurochir 151(11):1451–1457

    Article  PubMed  Google Scholar 

  20. Hadjipavlou AG, Katonis PK, Gaitanis IN, Muffoletto AJ, Tzermiadianos MN, Crow W (2004) Percutaneous transpedicular discectomy and drainage in pyogenic spondylodiscitis. Eur Spine J 13(8):707–713

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  21. Bettini N, Girardo M, Dema E, Cervellati S (2009) Evaluation of conservative treatment of non specific spondylodiscitis. Eur Spine J 18(1):143–150

    Article  PubMed  PubMed Central  Google Scholar 

  22. Brase A, Ringel F, Stüer C, Meyer B, Stoffel M (2010) Debridement and fusion with polyetheretherketone implants in purulent spondylodiscitis: a clinical experience with nine patients. Acta Neurochir 152(11):2001–2004

    Article  PubMed  Google Scholar 

  23. Schomacher M, Finger T, Koeppen D, Süss O, Vajkoczy P, Kroppenstedt S, Cabraja M (2014) Application of titanium and polyetheretherketone cages for treating pyogenic spondylodiscitis. Clin Neurol Neurosurg 127:65–70

    Article  PubMed  Google Scholar 

  24. Quaile A (2012) Infections associated with spinal implants. Int Orthop 36(2):451–456

    Article  PubMed  PubMed Central  Google Scholar 

  25. Lin Y, Li F, Chen W, Zeng H, Chen A, & Xiong W (2015). Single-level lumbar pyogenic spondylodiscitis treated with mini-open anterior debridement and fusion in combination with posterior percutaneous fixation via a modified anterior lumbar interbody fusion approach. J Neurosurg: Spine 1–7

  26. Lin TY, Tsai TT, Lu ML, Niu CC, Hsieh MK, Fu TS et al (2014) Comparison of two-stage open versus percutaneous pedicle screw fixation in treating pyogenic spondylodiscitis. BMC Musculoskelet Disord 15(1):443

    Article  PubMed  PubMed Central  Google Scholar 

  27. Madhavan K, Vanni S, Williams SK (2014) Direct lateral retroperitoneal approach for the surgical treatment of lumbar discitis and osteomyelitis. Neurosurg Focus 37(2), E5

    Article  PubMed  Google Scholar 

  28. Sheha AF (2011) Surgical management of post-discectomy spondylodiscitis with transforaminal lumbar interbody fusion (TLIF) and posterior instrumentation. Life Sci J 8(4)

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Shanmuganathan Rajasekaran.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Disclosures

None

Funding

Ganga Orthopaedic Research & Education Foundation (GOREF), Coimbatore.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Shetty, A.P., Aiyer, S.N., Kanna, R. et al. Pyogenic lumbar spondylodiscitis treated with transforaminal lumbar interbody fusion: safety and outcomes. International Orthopaedics (SICOT) 40, 1163–1170 (2016). https://doi.org/10.1007/s00264-015-3063-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00264-015-3063-5

Keywords

Navigation