Skip to main content
Log in

What types of degenerative lumbar pathologies respond to nerve root injection? A retrospective review of six hundred and forty one cases

  • Original Paper
  • Published:
International Orthopaedics Aims and scope Submit manuscript

Abstract

Purpose

Peri-radicular injection is a widely used procedure for treating lumbar radicular pain, but it remains unclear what types of lumbar pathologies respond well to this treatment. We aimed to investigate the efficacy of peri-radicular injection for degenerative lumbar disorders and to determine what types of pathologies respond well to this treatment.

Methods

We reviewed the records of 641 consecutive patients who underwent peri-radicular injection for degenerative lumbar pathologies with mean follow-up of 23.4 months. The pathologies included herniated disc in 286 patients, spinal stenosis in 141, degenerative spondylolisthesis in 136, failed back surgery in 24, isthmic spondylolisthesis in 22, degenerative scoliosis in 18, and foraminal stenosis in 14. Outcome measure was whether or not surgery is avoided by using peri-radicular injection. The rate of obviating surgery was determined in each pathology.

Results

Peri-radicular injection obviated surgeries in 331 patients (51.7 %). There were no complications related to the procedure, including neurological deterioration, infection, and haematoma. The rate of obviating surgery was 42.0 % in disc herniation, 52.9 % in degenerative spondylolisthesis, 67.4 % in spinal stenosis, 54.5 % in isthmic spondylolisthesis, 57.1 % in foraminal stenosis, 61.1 % in degenerative scoliosis and 54.1 % in failed back surgery. Poor outcomes were observed in herniated disc with spinal stenosis (17.9 % success), foraminal disc herniation (33.3 %), recurrent disc herniation (18.2 %) and failed back surgery with instability (33.3 %).

Conclusions

This study demonstrated that 51.7 % of patients with degenerative lumbar pathologies were successfully treated by peri-radicular injection. Efficacy was limited in cases of herniated disc with spinal stenosis, foraminal disc herniation, recurrent disc herniation and failed back surgery with instability.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Jonsson B, Stromqvist B, Annertz M et al (1988) Diagnostic lumbar nerve root block. J Spinal Disord 1:232–235

    CAS  PubMed  Google Scholar 

  2. Kikuchi S, Hasue M, Nishiyama K et al (1984) Anatomic and clinical studies of radicular symptoms. Spine 9:23–30

    Article  CAS  PubMed  Google Scholar 

  3. Cyteval C, Fescquet N, Thomas E et al (2006) Predictive factors of efficacy of periradicular corticosteroid injections for lumbar radiculopathy. AJNR Am J Neuroradiol 27:978–982

    CAS  PubMed  Google Scholar 

  4. van Akkerveeken PF (1993) The diagnostic value of nerve root sheath infiltration. Acta Orthop Scand Suppl 251:61–63

    Article  PubMed  Google Scholar 

  5. Krempen JF, Smith BS (1974) Nerve-root injection: a method for evaluating the etiology of sciatica. J Bone Joint Surg Am 56:1435–1444

    CAS  PubMed  Google Scholar 

  6. Herron LD (1989) Selective nerve root block in patient selection for lumbar surgery: surgical results. J Spinal Disord 2:75–79

    Article  CAS  PubMed  Google Scholar 

  7. Dooley JF, McBroom RJ, Taguchi T et al (1988) Nerve root infiltration in the diagnosis of radicular pain. Spine 13:79–83

    Article  CAS  PubMed  Google Scholar 

  8. DePalma MJ, Bhargava A, Slipman CW (2005) A critical appraisal of the evidence for selective nerve root injection in the treatment of lumbosacral radiculopathy. Arch Phys Med Rehabil 86:1477–1483

    Article  PubMed  Google Scholar 

  9. Bell GR, Rothman RH (1984) The conservative treatment of sciatica. Spine 9:54–56

    Article  CAS  PubMed  Google Scholar 

  10. Cherkin DC, Wheeler KJ, Barlow W et al (1998) Medication use for low back pain in primary care. Spine 23:607–614

    Article  CAS  PubMed  Google Scholar 

  11. Karppinen J, Malmivaara A, Kurunlahti M et al (2001) Periradicular infiltration for sciatica: a randomized controlled trial. Spine 26:1059–1067

    Article  CAS  PubMed  Google Scholar 

  12. Riew KD, Yin Y, Gilula L et al (2000) The effect of nerve-root injections on the need for operative treatment of lumbar radicular pain. A prospective, randomized, controlled, double-blind study. J Bone Joint Surg Am 82-A:1589–1593

    CAS  PubMed  Google Scholar 

  13. Ng LC, Sell P (2004) Outcomes of a prospective cohort study on peri-radicular infiltration for radicular pain in patients with lumbar disc herniation and spinal stenosis. Eur Spine J 13:325–329

    Article  PubMed Central  PubMed  Google Scholar 

  14. Riew KD, Park JB, Cho YS et al (2006) Nerve root blocks in the treatment of lumbar radicular pain. A minimum five-year follow-up. J Bone Joint Surg Am 88:1722–1725

    Article  PubMed  Google Scholar 

  15. Benoist M (2002) The natural history of lumbar disc herniation and radiculopathy. Joint Bone Spine 69:155–160

    Article  PubMed  Google Scholar 

  16. Weber H (1994) The natural history of disc herniation and the influence of intervention. Spine (Phila Pa 1976) 19:2234–2238, discussion 2233

    Article  CAS  Google Scholar 

  17. Yukawa Y, Kato F, Matsubara Y et al (1996) Serial magnetic resonance imaging follow-up study of lumbar disc herniation conservatively treated for average 30 months: relation between reduction of herniation and degeneration of disc. J Spinal Disord 9:251–256

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Masahiro Kanayama.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kanayama, M., Oha, F. & Hashimoto, T. What types of degenerative lumbar pathologies respond to nerve root injection? A retrospective review of six hundred and forty one cases. International Orthopaedics (SICOT) 39, 1379–1382 (2015). https://doi.org/10.1007/s00264-015-2761-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00264-015-2761-3

Keywords

Navigation