Skip to main content

Advertisement

Log in

Imaging of the acute scrotum: keys to a rapid diagnosis of acute scrotal disorders

  • Special Section: Male Pelvis
  • Published:
Abdominal Radiology Aims and scope Submit manuscript

Abstract

Imaging of the scrotum in the setting of acute symptoms such as pain or swelling is commonly performed emergently to differentiate between patients who require immediate surgery and those that do not. Acute scrotal symptoms are generally caused by infectious, traumatic or vascular etiologies. Rapid diagnosis and initiation of treatment is vital for testicular salvage in cases of acute testicular torsion, testicular rupture, and Fournier gangrene. Epididymitis, epididymo-orchitis, torsed testicular appendage, segmental testicular infarction, scrotal hematomas, testicular neoplasms, and acute idiopathic scrotal edema can have similar clinical presentations, but these conditions do not require immediate surgery. Ultrasound is the well-established first-line imaging modality for the acute scrotum. Contrast-enhanced ultrasound and magnetic resonance imaging can be useful as problem-solving tools when ultrasound studies are inconclusive or equivocal. This review describes normal scrotal anatomy and a wide range acute scrotal disorders, with emphasis on the imaging and clinical features that can minimize the risk of misdiagnosis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11
Fig. 12
Fig. 13
Fig. 14
Fig. 15
Fig. 16
Fig. 17
Fig. 18
Fig. 19

Similar content being viewed by others

References

  1. Middleton WD, Middleton MA, Dierks M, Keetch D, Dierks S (1997) Sonographic prediction of viability in testicular torsion: preliminary observations. J Ultrasound Med 16:23-27.

    Article  PubMed  CAS  Google Scholar 

  2. Remer EM, Casalino DD, Arellano RS et al (2012) ACR Appropriateness Criteria ® acute onset of scrotal pain–without trauma, without antecedent mass. Ultrasound Q 28:47-51.

    Article  PubMed  Google Scholar 

  3. Wang CL, Aryal B, Oto A, et al (2019) ACR Appropriateness Criteria: Acute Onset of Scrotal Pain-Without Trauma, Without Antecedent Mass. J Am Coll Radiol, 16:5:S38-S43.

    Article  PubMed  Google Scholar 

  4. Sidhu P, Cantisani V, Dietrich C, et al (2018) The EFSUMB Guidelines and Recommendations for the Clinical Practice of Contrast-Enhanced Ultrasound (CEUS) in Non-Hepatic Applications: Update 2017 (Long Version). Ultraschall Med 39:e2-e44.

    Article  PubMed  Google Scholar 

  5. Dogra V, Bhatt S (2004) Acute painful scrotum. Radiol Clin North Am 42:349-363.

    Article  PubMed  Google Scholar 

  6. Dogra VS, Gottlieb RH, Oka M, Rubens DJ (2003) Sonography of the scrotum. Radiology 227:18-36.

    Article  PubMed  Google Scholar 

  7. Guideline developed in collaboration with the American College of Radiology; Society for Pediatric Radiology; Society of Radiologists in Ultrasound (2015) AIUM Practice Guideline for the Performance of Scrotal Ultrasound Examinations. J Ultrasound Med 34:1-5.

    Google Scholar 

  8. Baud C, Veyrac C, Couture C, Ferran JL (1998) Spiral twist of the spermatic cord: a reliable sign of testicular torsion. Pediatr Radiol 28:950-954.

    Article  PubMed  CAS  Google Scholar 

  9. Kühn AL, Scortegagna E, Nowitzki KM, Kim YH (2016) Ultrasonography of the scrotum in adults. Ultrasonography 35:180-197.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Berger RE, Alexander ER, Harnisch JP, et al (1979) Etiology, manifestations and therapy of acute epididymitis: prospective study of 50 cases. J Urol 121:750-754.

    Article  PubMed  CAS  Google Scholar 

  11. Horstman WG, Middleton WD, Melson GL (1991) Scrotal inflammatory disease: color Doppler US findings. Radiology 179:55-59.

    Article  PubMed  CAS  Google Scholar 

  12. Keener TS, Winter TC, Nghiem HV, Schmiedl UP (1997) Normal adult epididymis: evaluation with color Doppler US. Radiology 202:712-714.

    Article  PubMed  CAS  Google Scholar 

  13. Lavallee ME, Cash J (2005) Testicular torsion: evaluation and management. Curr Sports Med Rep 4:102-104.

    Article  PubMed  Google Scholar 

  14. Fehily SR, Trubiano JA, McLean C, et al (2015) Testicular loss following bacterial epididymo-orchitis: Case report and literature review. Can Urol Assoc J 9:E148-E151.

    Article  PubMed  PubMed Central  Google Scholar 

  15. Green DB, Kawashima A, Menias CO, et al (2019) Complications of Intravesical BCG Immunotherapy for Bladder Cancer. Radiographics 39:80-94.

    Article  PubMed  Google Scholar 

  16. Lamm DL, van der Meijden PM, Morales A, et al (1992) Incidence and treatment of complications of bacillus Calmette-Guerin intravesical therapy in superficial bladder cancer. J Urol 147:596-600.

    Article  PubMed  CAS  Google Scholar 

  17. Demers V, Pelsser V (2012) “BCGitis”: A rare case of tuberculous epididymo-orchitis following intravesical Bacillus Calmette- Guérin therapy. J Radiol Case Rep 6:16-21.

    PubMed  PubMed Central  Google Scholar 

  18. Levenson RB, Singh AK, Novelline RA (2008) Fournier gangrene: role of imaging. Radiographics 28:519-528.

    Article  PubMed  Google Scholar 

  19. Yen Z, Wang HP, Ma HM, Chen SC, Chen WJ (2002) Ultrasonographic screening of clinically-suspected necrotizing fasciitis. Acad Emerg Med 9:1448-1451.

    Article  PubMed  Google Scholar 

  20. Zhao LC, Lautz TB, Meeks JJ, Maizels M (2011) Pediatric testicular torsion epidemiology using a national database: incidence, risk of orchiectomy and possible measures toward improving the quality of care. J Urol 186:2009-2013.

    Article  PubMed  Google Scholar 

  21. Lee FT Jr, Winter DB, Masden FA, et al (1996) Conventional color Doppler velocity sonography versus color Doppler energy sonography for the diagnosis of acute experimental torsion of the spermatic cord. AJR Am J Roentgenol 167:785-790.

    Article  PubMed  Google Scholar 

  22. Eaton SH, Cendron MA, Estrada CR, et al (2005) Intermittent testicular torsion: diagnostic features and management outcomes. J Urol 174:1532-1535.

    Article  PubMed  Google Scholar 

  23. Srinivasan A, Cinman N, Feber KM, Gitlin J, Palmer LS (2011) History and physical examination findings predictive of testicular torsion: an attempt to promote clinical diagnosis by house staff. J Pediatr Urol 7:470-474.

    Article  PubMed  Google Scholar 

  24. Frohlich LC, Paydar-Darian N, Cilento BG Jr, Lee LK (2017) Prospective Validation of Clinical Score for Males Presenting With an Acute Scrotum. Acad Emerg Med 24:1474-1482.

    Article  PubMed  Google Scholar 

  25. Baker LA, Sigman D, Mathews RI, Benson J, Docimo SG (2000) An analysis of clinical outcomes using color doppler testicular ultrasound for testicular torsion. Pediatrics 105:604-607.

    Article  PubMed  CAS  Google Scholar 

  26. Bentley DF, Ricchiuti DJ, Nasrallah PF, McMahon DR (2004) Spermatic cord torsion with preserved testis perfusion: initial anatomical observations. J Urol 172:2373-2376.

    Article  PubMed  Google Scholar 

  27. Cassar S, Bhatt S, Paltiel HJ, Dogra VS (2008) Role of spectral Doppler sonography in the evaluation of partial testicular torsion. J Ultrasound Med 27:1629-1638.

    Article  PubMed  Google Scholar 

  28. Dogra VS, Rubens DJ, Gottlieb RH, Bhatt S (2004) Torsion and beyond: new twists in spectral Doppler evaluation of the scrotum. J Ultrasound Med 23:1077-1085.

    Article  PubMed  Google Scholar 

  29. Munden MM, Williams JL, Zhang W, Crowe JE, Munden RF, Cisek LJ (2013) Intermittent testicular torsion in the pediatric patient: sonographic indicators of a difficult diagnosis. AJR Am J Roentgenol 201:912-918.

    Article  PubMed  Google Scholar 

  30. Kalfa N, Veyrac C, Baud C, Couture A, Averous M, Galifer RB (2004) Ultrasonography of the spermatic cord in children with testicular torsion: impact on the surgical strategy. J Urol 172:1692-1695.

    Article  PubMed  CAS  Google Scholar 

  31. Vijayaraghavan SB (2006) Sonographic differential diagnosis of acute scrotum: real-time whirlpool sign, a key sign of torsion. J Ultrasound Med 25:563-574.

    Article  PubMed  Google Scholar 

  32. Bayne CE, Villanueva J, Davis TD, Pohl HG, Rushton HG (2017) Factors Associated with Delayed Presentation and Misdiagnosis of Testicular Torsion: A Case-Control Study. J Pediatr 186:200-204.

    Article  PubMed  Google Scholar 

  33. Rafailidis V, Apostolou D, Charsoula A, Rafailidis D (2015) Sonography of the scrotum: from appendages to scrotolithiasis. J Ultrasound Med 34:507-518.

    Article  PubMed  Google Scholar 

  34. Sellars ME, Sidhu PS (2003) Ultrasound appearances of the testicular appendages: pictorial review. Eur Radiol 13:127-135.

    Article  PubMed  Google Scholar 

  35. Puri P, Boyd E (1976) Torsion of the appendix testis. A survey of 22 cases. Clin Pediatr (Phila) 15:949-950.

    Article  CAS  Google Scholar 

  36. Baldisserotto M, de Souza JC, Pertence AP, Dora MD (2005) Color Doppler sonography of normal and torsed testicular appendages in children. AJR Am J Roentgenol 184:1287-1292.

    Article  PubMed  Google Scholar 

  37. Skoglund RW, McRoberts JW, Ragde H (1970) Torsion of testicular appendages: presentation of 43 new cases and a collective review. J Urol 104:598-600.

    Article  PubMed  CAS  Google Scholar 

  38. Ruiz Montes AM, Jimenez Alvarez C, Nunez Nunez R, Cabrera R, Blesa Sanchez E (1994) [The clinical characteristics of patients with torsion of the testicular and epididymal appendages]. Cir Pediatr 7:140-142.

    PubMed  CAS  Google Scholar 

  39. Lev M, Ramon J, Mor Y, Jacobson JM, Soudack M (2015) Sonographic appearances of torsion of the appendix testis and appendix epididymis in children. J Clin Ultrasound 43:485-489.

    Article  PubMed  Google Scholar 

  40. Fernández-Pérez GC, Tardáguila FM, Velasco M, et al (2005) Radiologic findings of segmental testicular infarction. AJR Am J Roentgenol 184:1587-1593.

    Article  PubMed  Google Scholar 

  41. Bertolotto M, Derchi LE, Sidhu PS, et al (2011) Acute segmental testicular infarction at contrast-enhanced ultrasound: early features and changes during follow-up. AJR Am J Roentgenol 196:834-841.

    Article  PubMed  Google Scholar 

  42. Søreide K (2009) Epidemiology of major trauma. Br J Surg 96:697-698.

    Article  PubMed  Google Scholar 

  43. Bhatt S, Dogra VS (2008) Role of US in testicular and scrotal trauma. Radiographics 28:1617-1629.

    Article  PubMed  Google Scholar 

  44. Mulhall JP, Gabram SG, Jacobs LM (1995) Emergency management of blunt testicular trauma. Acad Emerg Med 2:639-643.

    Article  PubMed  CAS  Google Scholar 

  45. Morey AF, Brandes S, Dugi DD 3rd, et al; American Urological Association (2014) Urotrauma: AUA guideline. J Urol 192:327-335

  46. Lupetin AR, King W 3rd, Rich PJ, Lederman RB (1983) The traumatized scrotum: ultrasound evaluation. Radiology 148:203-207.

    Article  PubMed  CAS  Google Scholar 

  47. Buckley JC, McAninch JW (2006) Use of ultrasonography for the diagnosis of testicular injuries in blunt scrotal trauma. J Urol 175:175-178.

    Article  PubMed  Google Scholar 

  48. Guichard G, El Ammari J, Del Coro C, et al (2008) Accuracy of ultrasonography in diagnosis of testicular rupture after blunt scrotal trauma. Urology 71:52-56.

    Article  PubMed  Google Scholar 

  49. Deurdulian C, Mittelstaedt CA, Chong WK, Fielding JR (2007) US of acute scrotal trauma: optimal technique, imaging findings, and management. Radiographics 27:357-369.

    Article  PubMed  Google Scholar 

  50. Bowen DK, Gonzalez CM (2014) Intratesticular hematoma after blunt scrotal trauma: a case series and algorithm-based approach to management. Cent European J Urol 67:427-429.

    Article  PubMed  PubMed Central  Google Scholar 

  51. Lynch TH, Martínez-Piñeiro L, Plas E, et al; European Association of Urology (2005) EAU guidelines on urological trauma. Eur Urol 47:1-15

  52. Morey AF, Metro MJ, Carney KJ, Miller KS, McAninch JW (2004) Consensus on genitourinary trauma: external genitalia. BJU Int 94:507-515.

    Article  PubMed  Google Scholar 

  53. Bleyer A, O’Leary M, Barr R, Ries LAG (eds) (2006) Cancer Epidemiology in Older Adolescents and Young Adults 15 to 29 Years of Age, Including SEER Incidence and Survival: 1975-2000. National Cancer Institute, NIH Pub. No. 06-5767. Bethesda, Maryland.

  54. Mesquita RD, Rosas JL (2017) Adult Acute Scrotal Edema - When Radiologists Can Help to Avoid Unnecessary Surgical Treatment. J Radiol Case Rep 11:24-30.

    PubMed  PubMed Central  Google Scholar 

  55. Breen M, Murphy K, Chow J, Kiely E, O’Regan K (2013) Acute idiopathic scrotal edema. Case Rep Urol 2013:829345.

    PubMed  PubMed Central  Google Scholar 

  56. Santi M, Lava SAG, Simonetti GD, Bianchetti MG, Milani GP (2018) Acute idiopathic scrotal edema: Systematic literature review. Eur J Pediatr Surg 28:222-226.

    Article  PubMed  Google Scholar 

  57. Bueschen AJ (1990) Flank pain. In: Walker HK, Hall WD, Hurst JW (eds) Clinical methods: The history, physical, and laboratory examinations, 3rd edn, chap 182. Butterworths, Boston.

    Google Scholar 

  58. McGee SR (1993) Referred scrotal pain: case reports and review. J Gen Intern Med 8:694-701.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Erick M. Remer.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

CME activity This article has been selected as the CME activity for the current month. Please visit https://ce.mayo.edu/node/99487 and follow the instructions to complete this CME activity.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sweet, D.E., Feldman, M.K. & Remer, E.M. Imaging of the acute scrotum: keys to a rapid diagnosis of acute scrotal disorders. Abdom Radiol 45, 2063–2081 (2020). https://doi.org/10.1007/s00261-019-02333-4

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00261-019-02333-4

Keywords

Navigation