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A novel core biopsy needle with shorter dead space for percutaneous image-guided musculoskeletal biopsies — how does it compare with an established core biopsy needle?

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Abstract

Purpose

To compare diagnostic yield and utility of a novel core biopsy needle (NCBN) with shortened tip dead space for percutaneous musculoskeletal biopsies with an established core biopsy needle (ECBN).

Methods

This study was IRB approved and HIPAA compliant. All percutaneous biopsies using an NCBN performed between July 2020 and August 2021 were retrospectively reviewed. Data on patient demographics, biopsy technique, biopsy needle, and histopathology were collated.

Results

Thirty-six patients were included in this study, 16 (44%) undergoing biopsy with both an NCBN and an ECBN, and 20 (56%) with an NCBN only. All 36 NCBN biopsies were 16 gauge. Fifteen (94%) of the ECBN biopsies were 14 gauge, and 1 (6%) was 16 gauge. Thirty-four (94%) of the NCBN and 15 (94%) of the ECBN biopsies were diagnostic. No adverse events were identified.

Conclusion

Both the NCBN and ECBN have high diagnostic rates. No adverse events were identified. NCBN could be considered for biopsy of lesions limited by anatomic location or near adjacent critical structures.

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References

  1. Fraser-Hill MA, Renfrew DL. Percutaneous needle biopsy of musculoskeletal lesions. 1. Effective accuracy and diagnostic utility. AJR Am J Roentgenol. 1992;158:809–12.

    Article  CAS  Google Scholar 

  2. Fraser-Hill MA, Renfrew DL, Hilsenrath PE. Percutaneous needle biopsy of musculoskeletal lesions. 2. Cost-effectiveness. AJR Am J Roentgenol. 1992;158:813–8.

    Article  CAS  Google Scholar 

  3. Wu JS, Goldsmith JD, Horwich PJ, Shetty SK, Hochman MG. Bone and soft-tissue lesions: what factors affect diagnostic yield of image-guided core-needle biopsy? Radiology. 2008;248:962–70.

    Article  Google Scholar 

  4. Kilpatrick SE, Cappellari JO, Bos GD, Gold SH, Ward WG. Is fine-needle aspiration biopsy a practical alternative to open biopsy for the primary diagnosis of sarcoma? Experience with 140 patients. Am J Clin Pathol. 2001;115:59–68.

    Article  CAS  Google Scholar 

  5. Li NP, Wingfield MA, Mills MK, Beckett BR, Hansford BG. Percutaneous image-guided sternal biopsy: a cross-institutional retrospective review of diagnostic yield and safety in 50 cases. Skeletal Radiol. 2021;50:495–504.

    Article  Google Scholar 

  6. Li Y, Du Y, Luo TY, Yang HF, Yu JH, Xu XX, et al. Factors influencing diagnostic yield of CT-guided percutaneous core needle biopsy for bone lesions. Clin Radiol. 2014;69:e43-47.

    Article  CAS  Google Scholar 

  7. Husseini JS, Simeone FJ, Nelson SB, Chang CY. CT-guided discitis-osteomyelitis biopsies: needle gauge and microbiology results. Skeletal Radiol. 2020;49:1431–9.

    Article  Google Scholar 

  8. Chang CY, Huang AJ, Bredella MA, Torriani M, Halpern EF, Rosenthal DI, et al. Percutaneous CT-guided needle biopsies of musculoskeletal tumors: a 5-year analysis of non-diagnostic biopsies. Skeletal Radiol. 2015;44:1795–803.

    Article  Google Scholar 

  9. Chang I-YJ, Ilaslan H, Sundaram M, Schils J, Subhas N. CT-guided percutaneous biopsy of sclerotic bone lesions: diagnostic outcomes. Skeletal Radiol. 2018;47:661–9.

    Article  Google Scholar 

  10. De Filippo M, Saba L, Rossi E, Nizzoli R, Tiseo M, Pedrazzi G, et al. Curved needles in CT-guided fine needle biopsies of abdominal and retroperitoneal small lesions. Cardiovasc Intervent Radiol. 2015;38:1611–6.

    Article  Google Scholar 

  11. Cazzato RL, Garnon J, Shaygi B, Caudrelier J, Bauones S, Tsoumakidou G, et al. Performance of a new blunt-tip coaxial needle for percutaneous biopsy and drainage of “hard-to-reach” targets. Cardiovasc Intervent Radiol. 2017;40:1431–9.

    Article  Google Scholar 

  12. AprioCore® plus - US ONLY [Internet]. AprioMed. [cited 2022 May 16]. Available from: https://apriomed.com/products/apriocore-plus-us-only/

  13. Khalilzadeh O, Baerlocher MO, Shyn PB, Connolly BL, Devane AM, Morris CS, et al. Proposal of a new adverse event classification by the Society of Interventional Radiology Standards of Practice Committee. J Vasc Interv Radiol. 2017;28:1432-1437.e3.

    Article  Google Scholar 

  14. TEMNO Evolution® Biopsy Device [Internet]. Merit Medical. [cited 2022 May 19]. Available from: https://www.merit.com/peripheral-intervention/biopsy/soft-tissue-biopsy/temno-evolution-biopsy-device/

  15. Pritzker KPH, Nieminen HJ. Needle biopsy adequacy in the era of precision medicine and value-based health care. Arch Pathol Lab Med. 2019;143:1399–415.

    Article  CAS  Google Scholar 

  16. Crenn V, Vezole L, Bouhamama A, Meurgey A, Karanian M, Marec-Bérard P, et al. Percutaneous core needle biopsy can efficiently and safely diagnose most primary bone tumors. Diagnostics (Basel). 2021;11:1552.

    Article  Google Scholar 

  17. Le HBQ, Lee ST, Munk PL. Image-guided musculoskeletal biopsies. Semin Intervent Radiol. 2010;27:191–8.

    Article  Google Scholar 

  18. Filippiadis DK, Charalampopoulos G, Mazioti A, Keramida K, Kelekis A. Bone and soft-tissue biopsies: what you need to know. Semin Intervent Radiol. 2018;35:215–20.

    Article  Google Scholar 

  19. Didolkar MM, Anderson ME, Hochman MG, Rissmiller JG, Goldsmith JD, Gebhardt MG, et al. Image guided core needle biopsy of musculoskeletal lesions: are nondiagnostic results clinically useful? Clin Orthop Relat Res. 2013;471:3601–9.

    Article  Google Scholar 

  20. Rimondi E, Rossi G, Bartalena T, Ciminari R, Alberghini M, Ruggieri P, et al. Percutaneous CT-guided biopsy of the musculoskeletal system: results of 2027 cases. Eur J Radiol. 2011;77:34–42.

    Article  Google Scholar 

  21. Abboud S, Kosaraju V, Bhatt A, Egler R, Elliott R, Faraji N, et al. Multidisciplinary approach for repeat musculoskeletal lesion biopsy after nondiagnostic initial sampling: a 10-year single-center experience. J Surg Oncol. 2021;123:342–51.

    Article  Google Scholar 

  22. Ramkumar DB, Kelly SP, Ramkumar N, Gyftopoulos S, Raskin KA, Lozano-Calderon SA, et al. Adjunct diagnostic strategies in improving diagnostic yields in image-guided biopsies of musculoskeletal neoplasms—a cost-effectiveness analysis. J Surg Oncol. 2021;124:1499–507.

    Article  Google Scholar 

  23. MissionTM Disposable Core Biopsy Instrument [Internet]. [cited 2022 May 16]. Available from: https://www.bd.com/en-us/products-and-solutions/products/product-families/mission-disposable-core-biopsy-instrument

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Correspondence to Connie Y. Chang.

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Ethics approval

All procedures performed in studies involving human subjects were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This study was approved by the Partners Human Research IRB.

Consent to participate

The study was approved by the local Institutional Review Board (IRB) and HIPAA compliant. The study was considered exempt from consent because of the retrospective study design.

Conflict of interest

The authors declare no competing interests.

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Cahalane, A.M., Habib, U., Balza, R. et al. A novel core biopsy needle with shorter dead space for percutaneous image-guided musculoskeletal biopsies — how does it compare with an established core biopsy needle?. Skeletal Radiol 52, 99–109 (2023). https://doi.org/10.1007/s00256-022-04130-5

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  • DOI: https://doi.org/10.1007/s00256-022-04130-5

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