Abstract
Aneurysmal bone cyst (ABC) is a benign locally destructive lesion that usually developed in the bone cavity of bones, less commonly on the surface of cortical bones and very rarely develop outside the bone. There are only 35 reports of extraskeletal aneurysmal bone cyst (ESABC) in the English literature. We report a case of a 12-year-old female with no history of trauma who presented with knee pain. Imaging studies revealed an infrapatellar mass that was fast to calcify during a period of 3 months. MRI showed high T2 center, low T1 signal, and heterogenic enhancement with a rim of low intensity consistent with calcified boarders surrounded by severe soft tissue edema. The lesion was surgically excised, and a histological examination revealed an aneurysmal bone cyst possibly arising within myositis ossificans or heterotopic ossification. In her last follow-up 1.5 years after the surgical excision, the patient was symptom free and without signs of recurrence. To the best of our knowledge, this is the first reported case of an intra-articular ESABC located in the knee.
Similar content being viewed by others
References
Fletcher CDM, Unni KK, Mertens F, Weltgesundheitsorganisation, International Agency for Research on Cancer, editors. Pathology and genetics of tumours of soft tissue and bone ; [the WHO classification of tumours of soft tissue and bone presented in this book reflects the views of a working group that convened for an editorial and consensus conference in Lyon, France, April 24–28, 2002]. Lyon: IARC Press; 2002. 427. (World Health Organization Classification of tumours).
Shooshtarizadeh T, Movahedinia S, Mostafavi H, Jamshidi K, Sami SH. Aneurysmal bone cyst: an analysis of 38 cases and report of four unusual surface ones. Arch Bone Jt Surg. 2016;4(2):7.
Meohas W, de Sá Lopes AC, da Silveira Möller JV, Barbosa LD, Oliveira MB dos R. Parosteal aneurysmal bone cyst. Rev Bras Ortop Engl Ed. 2015;50(5):601–6.
Lopez LV, Rodriguez MG, Siegal GP, Wei S. Extraskeletal aneurysmal bone cyst: report of a case and review of the literature. Pathol Res Pract. 2017;213(11):1445–9.
Salm R, Sissons HA. Giant-cell tumours of soft tissues. J Pathol. 1972;107(1):27–39.
Song W, Suurmeijer AJH, Bollen SM, Cleton-Jansen A-M, Bovée JVMG, Kroon HM. Soft tissue aneurysmal bone cyst: six new cases with imaging details, molecular pathology, and review of the literature. Skelet Radiol. 2019;48(7):1059–67.
Petrik PK, Findlay JM, Sherlock RA. Aneurysmal cyst, bone type, primary in an artery. Am J Surg Pathol. 1993;17(10):1062–6.
Shannon P, Bedard Y, Bell R, Kandel R. Aneurysmal cyst of soft tissue: report of a case with serial magnetic resonance imaging and biopsy. Hum Pathol. 1997;28(2):255–7.
Samura H, Shiraishi M, Tokashiki H, Nosato E, Miyazato H, Muto Y. An extraosseous aneurysmal cyst in the pelvic cavity: report of a case. Clin Imaging. 2000;24(2):68–71.
D’Costa GF, Hastak MS, Patil YV. Primary aneurysmal cyst: bone type in the breast. Indian J Surg. 2007;69(6):248–50.
Chung IA, Petelin K, Pižem J, Luzar B. Cutaneous aneurysmal bone cyst—first report of a case and literature review. J Cutan Pathol. 2019;46(11):858–63.
Park HY, Yang SK, Sheppard WL, Hegde V, Zoller SD, Nelson SD, et al. Current management of aneurysmal bone cysts. Curr Rev Musculoskelet Med. 2016;9(4):435–44.
Baker KS, Gould ES, Patel HB, Hwang SJ. Soft tissue aneurysmal bone cyst: a rare case in a middle aged patient. J Radiol Case Rep. 2015;9(1):26–35.
Kransdorf MJ, Sweet DE. Aneurysmal bone cyst: concept, controversy, clinical presentation, and imaging. Am J Roentgenol. 1995;164(3):573–80.
Hao Y, Wang L, Yan M, Jin F, Ge S, Dai K. Soft tissue aneurysmal bone cyst in a 10-year-old girl. Oncol Lett. 2012;3(3):545–8.
López-Barea F, Rodríguez-Peralto JL, Burgos-Lizaldez E, Alvarez-Linera J, Sánchez-Herrera S. Primary aneurysmal cyst of soft tissue. Report of a case with ultrastructural and MRI studies. Virchows Arch Int J Pathol. 1996;428(2):125–9.
Ajilogba KA, Kaur H, Duncan R, McFarlane JH, Watt AJ. Extraosseous aneurysmal bone cyst in a 12-year-old girl. Pediatr Radiol. 2005;35(12):1240–2.
Mulcahy H, Hoch B. An extraskeletal para-articular osteochondroma of Hoffa’s fat pad. Radiol Case Rep. 2010;5(4):420.
Nielsen GP, Smith MA, Rosenberg AE. Soft tissue aneurysmal bone cyst. Am J Surg Pathol. 2002;26(1):6.
Bahk W-J, Mirra JM. Differential diagnostic value of “blue reticulated chondroid-like material” in aneurysmal bone cysts. Am J Clin Pathol. 2015;143(6):823–9.
Amir G, Mogle P, Sucher E. Case report 729. Myositis ossificans and aneurysmal bone cyst. Skelet Radiol. 1992;21(4):257–9.
Sukov WR, Franco MF, Erickson-Johnson M, Chou MM, Unni KK, Wenger DE, et al. Frequency of USP6 rearrangements in myositis ossificans, brown tumor, and cherubism: molecular cytogenetic evidence that a subset of “myositis ossificans-like lesions” are the early phases in the formation of soft-tissue aneurysmal bone cyst. Skelet Radiol. 2008;37(4):321–7.
Rodríguez-Peralto JL, López-Barea F, Sánchez-Herrera S, Atienza M. Primary aneurysmal cyst of soft tissues (extraosseous aneurysmal cyst). Am J Surg Pathol. 1994;18(6):632–6.
Wang XL, Gielen JL, Salgado R, Delrue F, De Schepper AMA. Soft tissue aneurysmal bone cyst. Skelet Radiol. 2004;33(8):477–80.
Ellison DA, Sawyer JR, Parham DM, Nicholas R. Soft-tissue aneurysmal bone cyst: report of a case with t(5;17)(q33;p13). Pediatr Dev Pathol. 2007;10(1):46–9.
Karkuzhali P, Bhattacharyya M, Sumitha P. Multiple soft tissue aneurysmal cysts: an occurrence after resection of primary aneurysmal bone cyst of fibula. Indian J Orthop. 2007;41(3):246.
An SB, Choi J-A, Chung J-H, Oh JH, Kang HS. Giant cell tumor of soft tissue: a case with atypical US and MRI findings. Korean J Radiol. 2008;9(5):462.
Sahu A, Gujral SS, Gaur S. Extraosseous aneurysmal cyst in hand: a case report. Cases J. 2008;1(1):268.
Pietschmann MF, Oliveira AM, Chou MM, Ihrler S, Niederhagen M, Baur-Melnyk A, et al. Aneurysmal bone cysts of soft tissue represent true neoplasms: a report of two cases. J Bone Jt Surg Am. 2011;93(9):e45 -1–8.
Jacquot C, Szymanska J, Nemana LJ, Steinbach LS, Horvai AE. Soft-tissue aneurysmal bone cyst with translocation t(17;17)(p13;q21) corresponding to COL1A1 and USP6 loci. Skelet Radiol. 2015;44(11):1695–9.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no conflict of interest.
Additional information
Publisher’s note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Olshinka, N., Azraq, Y., Benshushan, S. et al. Knee intra-articular extraskeletal aneurysmal bone cyst: a case report and review of literature. Skeletal Radiol 49, 1499–1503 (2020). https://doi.org/10.1007/s00256-020-03464-2
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00256-020-03464-2