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Bladder cancer presenting with acrometastases: a different cause of foot pain

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Abstract

Acrometastasis means tumor seeding distally to the elbow or the knee and is an uncommon event. Foot acrometastases occur in 0.58% of patients with skeletal metastases overall, and only about 10% of these are caused by bladder cancer. We present a case of bladder cancer manifesting with insidious foot pain, caused by multiple lytic lesions located solely at the left foot. It was suspected after whole-body CT and later confirmed by biopsy result. We enumerate the differential diagnosis of distal extremity lytic lesions for educational purposes and review the literature listing similar published cases.

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Acknowledgements

We would like to thank Hossei Imenpour, MD, and Raffaella Pratesi, MD for providing the histologic images.

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Authors and Affiliations

  1. Dipartimento di Scienze della Salute, Universita degli Studi di Genova, Via Antonio Pastore, 1, 16132, Genoa, Italy

    João Matos & Ilaria Mussetto

  2. Department of Radiology, Ospedale Villa Scassi – Sampierdarena, Corso Scassi 1, 16121, Genoa, Italy

    Raffaella Podestà, Daria Schettini & Nicoletta Gandolfo

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  1. João Matos
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  2. Ilaria Mussetto
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  3. Raffaella Podestà
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  4. Daria Schettini
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  5. Nicoletta Gandolfo
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Correspondence to João Matos.

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Matos, J., Mussetto, I., Podestà, R. et al. Bladder cancer presenting with acrometastases: a different cause of foot pain. Skeletal Radiol 47, 1003–1009 (2018). https://doi.org/10.1007/s00256-018-2888-6

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  • DOI: https://doi.org/10.1007/s00256-018-2888-6

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