Abstract
Contrast-enhanced ultrasound (CEUS) and diffusion-weighted imaging (DWI) are safe, repeatable imaging techniques. The aim of this paper is to discuss the advantages, technical factors and possible clinical applications of these imaging tools in focal renal lesions in children.
Similar content being viewed by others
References
Rosado E, Riccabona M (2016) Off-label use of ultrasound contrast agents for intravenous applications in children: analysis of the existing literature. J Ultrasound Med 35:487–496
Darge K, Papadopoulou F, Ntoulia A et al (2013) Safety of contrast-enhanced ultrasound in children for non-cardiac applications: a review by the Society for Pediatric Radiology (SPR) and the international contrast ultrasound society (ICUS). Pediatr Radiol 43:1063–1073
Piskunowicz M, Kosiak W, Batko T et al (2015) Safety of intravenous application of second-generation ultrasound contrast agent in children: prospective analysis. Ultrasound Med Biol 41:1095–1099
Riccabona M (2012) Application of a second-generation US contrast agent in infants and children - a European questionnaire-based survey. Pediatr Radiol 42:1471–1480
Riccabona M, Avni FE, Damasio MB et al (2012) ESPR uroradiology task force and ESUR paediatric working group--imaging recommendations in paediatric uroradiology, part V: childhood cystic kidney disease, childhood renal transplantation and contrast-enhanced ultrasonography in children. Pediatr Radiol 42:1275–1283
Sidhu PS, Cantisani V, Deganello A et al (2017) Role of contrast-enhanced ultrasound (CEUS) in Paediatric practice: an EFSUMB position statement. Ultraschall Med 38:33–43
Ntoulia A, Anupindi SA, Darge K, Back SJ (2018) Applications of contrast-enhanced ultrasound in the pediatric abdomen. Abdom Radiol 43:948–959
Stenzel M, Mentzel HJ (2014) Ultrasound elastography and contrast-enhanced ultrasound in infants, children, and adolescents. Eur J Radiol 83:1560–1569
Knieling F, Strobel D, Rompel O et al (2016) Spectrum, applicability and diagnostic capacity of contrast-enhanced ultrasound in pediatric patients and young adults after intravenous application – a retrospective trail. Ultraschall Med 37:619–626
Piscaglia F, Nolsøe C, Dietrich CF et al (2012) The EFSUMB guidelines and recommendations on the clinical practice of contrast enhanced ultrasound (CEUS): update 2011 on non-hepatic applications. Ultraschall Med 33:33–59
Harvey CJ, Sidhu PS, Bachmann Nielsen M (2013) Contrast-enhanced ultrasound in renal transplants: applications and future directions. Ultraschall Med 34:319–321
Stein R, Dogan HS, Hoebeke P et al (2015) Urinary tract infections in children: EAU/ESPU guidelines. Eur Urol 67:546–558
Granata A, Floccari F, Insalaco M et al (2012) Ultrasound assessment in renal infections. G Ital Nefrol 29 Suppl 5:S47–S57
Yusuf GT, Sellars ME, Huang DY et al (2014) Cortical necrosis secondary to trauma in a child: contrast-enhanced ultrasound comparable to magnetic resonance imaging. Pediatr Radiol 44:484–487
Fontanilla T, Minaya J, Cortès C et al (2012) Acute complicated pyelonephritis: contrast-enhanced ultrasound. Abdom Imaging 37:639–646
Hains DS, Cohen HL, McCarville MB et al (2017) Elucidation of renal scars in children with vesicoureteral reflux using contrast-enhanced ultrasound: a pilot study. Kidney Int Rep 2:420–424
Karmazyn B, Tawadros A, Delaney LR et al (2015) Ultrasound classification of solitary renal cysts in children. J Pediatr Urol 11:149.e1–149.e6
Clevert DA, Minaifar N, Weckbach S et al (2008) Multislice computed tomography versus contrast-enhanced ultrasound in evaluation of complex cystic renal masses using the Bosniak classification system. Clin Hemorheol Microcirc 39:171–178
Oon SF, Foley RW, Quinn D et al (2018) Contrast-enhanced ultrasound of the kidney: a single-institution experience. Ir J Med Sci 187:795–802
Catalano O, Aiani L, Barozzi L et al (2009) CEUS in abdominal trauma: multi-center study. Abdom Imaging 34:225–234
Anuponidi SA, Biko DM, Ntoulia A et al (2017) Contrast-enhanced US assessment of focal liver lesions in children. Radiographics 37:1632–1647
Amerstorfer EE, Haberlik A, Riccabona M (2015) Imaging assessment of renal injuries in children and adolescents: CT or ultrasound? J Pediatr Surg 50:448–455
Sessa B, Trinci M, Ianniello S et al (2015) Blunt abdominal trauma: role of contrast-enhanced ultrasound (CEUS) in the detection and staging of abdominal traumatic lesions compared to US and CE-MDCT. Radiol Med 120:180–189
Miele V, Piccolo CL, Galluzzo M et al (2016) Contrast-enhanced ultrasound (CEUS) in blunt abdominal trauma. Br J Radiol 89:20150823
Armstrong LB, Mooney DP, Paltiel H et al (2018) Contrast enhanced ultrasound for the evaluation of blunt pediatric abdominal trauma. J Pediatr Surg 53:548–552
Streck CJ Jr, Jewett BM, Wahlquist AH et al (2012) Evaluation for intra-abdominal injury in children after blunt torso trauma: can we reduce unnecessary abdominal computed tomography by utilizing a clinical prediction model? J Trauma Acute Care Surg 73:371–376
Cokkinos D, Antypa E, Stefanidis K et al (2012) Contrast-enhanced ultrasound for imaging blunt abdominal trauma - indications, description of the technique and imaging review. Ultraschall Med 33:60–67
Miele V, Piccolo CL, Trinci M et al (2016) Diagnostic imaging of blunt abdominal trauma in pediatric patients. Radiol Med 121:409–430
Lim HK, Kim JK, Kim KA, Cho KS (2009) Prostate cancer: apparent diffusion coefficient map with T2-weighted images for detection -- a multireader study. Radiology 250:145–151
Parikh T, Drew SJ, Lee VS et al (2008) Focal liver lesion detection and characterization with diffusion-weighted MR imaging: comparison with standard breath-hold T2-weighted imaging. Radiology 246:812–822
Ei Khouli RH, Jacobs MA, Mezban SD et al (2010) Diffusion-weighted imaging improves the diagnostic accuracy of conventional 3.0-T breast MR imaging. Radiology 256:64–73
Mytsyk Y, Dutka I, Borys Y et al (2017) Renal cell carcinoma: applicability of the apparent coefficient of the diffusion-weighted estimated by MRI for improving their differential diagnosis, histologic subtyping, and differentiation grade. Int Urol Nephrol 49:215–224
Prasad SR, Humphrey PA, Catena JR et al (2006) Common and uncommon histologic subtypes of renal cell carcinoma: imaging spectrum with pathologic correlation. Radiographics 26:1795–1806
Lair M, Renaux-Petel M, Hassani A et al (2018) Diffusion tensor imaging in acute pyelonephritis in children. Pediatr Radiol 48:1081–1085
Vivier PH, Sallem A, Beurdeley M et al (2014) MRI and suspected acute pyelonephritis in children: comparison of diffusion-weighted imaging with gadolinium-enhanced T1-weighted imaging. Eur Radiol 24:19–25
Bosakova A, Salounova D, Havelka J et al (2018) Diffusion-weighted magnetic resonance imaging is more sensitive than dimercaptosuccinic acid scintigraphy in detecting parenchymal lesions in children with acute pyelonephritis: a prospective study. J Pediatr Urol 14:269.e1–269.e7
Littooij AS, Nikkels PG, Hulsbergen-van de Kaa CA et al (2017) Apparent diffusion coefficient as it relates to histopathology findings in post-chemotherapy nephroblastoma: a feasibility study. Pediatr Radiol 47:1608–1614
Littooij AS, Humphries PD, Olsen ØE (2015) Intra- and interobserver variability of whole-tumour apparent diffusion coefficient measurements in nephroblastoma: a pilot study. Pediatr Radiol 45:1651–1660
Littooij AS, Sebire NJ, Olsen ØE (2017) Whole-tumor ADC measurements in nephroblastoma: can it identify blastemal predominance? J Magn Reson Imaging 45:1316–1324
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflicts of interest
None
Additional information
Publisher’s note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Damasio, M.B., Ording Müller, LS., Augdal, T.A. et al. European Society of Paediatric Radiology abdominal imaging task force: recommendations for contrast-enhanced ultrasound and diffusion-weighted imaging in focal renal lesions in children. Pediatr Radiol 50, 297–304 (2020). https://doi.org/10.1007/s00247-019-04552-9
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00247-019-04552-9