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Twenty-Year Experience with Truncus Arteriosus Repair: Changes in Risk Factors in the Current Era

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Abstract

Although the clinical outcomes of truncus arteriosus (TA) repair have been improving, few data are available on long-term outcomes after truncus arteriosus repair in the current era. This study evaluated long-term outcome after repair of TA. Fifty-one patients underwent total correction from April 1982 to June 2018. Since 2003, perioperative strategy has changed to minimal priming volume, modified ultrafiltration, and early total repair (n = 26). Mortality and reoperation rates were analyzed before and after 2003. There were 8 hospital deaths after initial operation, all before 1997. During the mean follow-up of 9.8 years, there were 2 deaths. The Kaplan–Meier estimate of survival among all hospital survivors was 94.7% at 5 years and 88.0% at 20 years. A significant independent risk factor for early mortality was operation before 2003 (Hazard ratio (HR) 9.710, p = 0.041) and REV operation (HR 8.000, p = 0.028). Freedom from reoperation for conduit change and TV repair were 88.3% and 41% at 1 and 5 years, and 96.2% and 85.4% at 1 and 5 years, respectively. After 2003, younger age and conduit choice were risk factors for conduit-related reoperation. Initial preoperative TV regurgitation was independent risk factor for sequential TV repair. Patients with TA can undergo total repair of TA with excellent results, especially in current era. Most of the patients require conduit-related reoperations. Younger age and the methods of RVOT reconstruction were risk factors for conduit-related reoperations. TV repair is necessary in limited patients, and initial regurgitation was a risk factor.

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References

  1. Thompson LD, McElhinney DB, Reddy M, Petrossian E, Silverman NH, Hanley FL (2001) Neonatal repair of truncus arteriosus: continuing improvement in outcomes. Ann Thorac Surg 72:391–395

    Article  CAS  Google Scholar 

  2. Ullmann MV, Gorenflo M, Sebening C, Ulmer HE, Hagl S (2003) Long-term results after repair of truncus arteriosus communis in neonates and infants. Thorac Cardiovasc Surg 51:175–179

    Article  CAS  Google Scholar 

  3. Tlaskal T, Chaloupecky V, Hucin B et al (2010) Long-term results after correction of persistent truncus arteriosus in 83 patients. Eur J Cardiothorac Surg 37:1278–1284

    Article  Google Scholar 

  4. Kalavrouziotis G, Purohit M, Ciotti G, Corno AF, Pozzi M (2006) Truncus arteriosus communis: Early and midterm results of early primary repair. Ann Thorac Surg 82:2200–2206

    Article  Google Scholar 

  5. Vohra HA, Whistance RN, Chia AX et al (2010) Long-term follow-up after primary complete repair of common arterial trunk with homograft: a 40-year experience. J Thorac Cardiovasc Surg 140:325–329

    Article  Google Scholar 

  6. Russell HM, Pasquali SK, Jacobs JP et al (2012) Outcomes of repair of common arterial trunk with truncal valve surgery: a review of the society of thoracic surgeons congenital heart surgery database. Ann Thorac Surg 93:164–169 discussion 169

    Article  Google Scholar 

  7. Jahangiri M, Zurakowski D, Mayer JE, del Nido PJ, Jonas RA (2000) Repair of the truncal valve and associated interrupted arch in neonates with truncus arteriosus. J Thorac Cardiovasc Surg 119:508–514

    Article  CAS  Google Scholar 

  8. Sinzobahamvya N, Asfour B, Boscheinen M et al (2007) Compared fate of small-diameter contegras and homografts in the pulmonary position. Eur J Cardiothorac Surg 32:209–214

    Article  Google Scholar 

  9. Urban AE, Sinzobahamvya N, Brecher AM, Wetter J, Malorny S (1998) Truncus arteriosus: ten-year experience with homograft repair in neonates and infants. Ann Thorac Surg 66(Suppl):S183–188

    Article  CAS  Google Scholar 

  10. Brown JW, Ruzmetov M, Okada Y, Vijay P, Turrentine MW (2001) Truncus arteriosus repair: Outcomes, risk factors, reoperation and management. Eur J Cardiothorac Surg 20:221–227

    Article  CAS  Google Scholar 

  11. Boethig D, Goerler H, Westhoff-Bleck M et al (2007) Evaluation of 188 consecutive homografts implanted in pulmonary position after 20 years. Eur J Cardiothorac Surg 32:133–142

    Article  Google Scholar 

  12. McElhinney DB, Rajasinghe HA, Mora BN, Reddy VM, Silverman NH, Hanley FL (2000) Reinterventions after repair of common arterial trunk in neonates and young infants. J Am Coll Cardiol 35:1317–1322

    Article  CAS  Google Scholar 

  13. Meyns B, Jashari R, Gewillig M et al (2005) Factors influencing the survival of cryopreserved homografts. The second homograft performs as well as the first. Eur J Cardiothorac Surg 28:211–216

    Article  Google Scholar 

  14. Lacour-Gayet F, Serraf A, Komiya T et al (1996) Truncus arteriosus repair: Influence of techniques of right ventricular outflow tract reconstruction. J Thorac Cardiovasc Surg 111:849–856

    Article  CAS  Google Scholar 

  15. Danton MH, Barron DJ, Stumper O et al (2001) Repair of truncus arteriosus: a considered approach to right ventricular outflow tract reconstruction. Eur J Cardiothorac Surg 20:95–103

    Article  CAS  Google Scholar 

  16. Henaine R, Azarnoush K, Belli E et al (2008) Fate of the truncal valve in truncus arteriosus. Ann Thorac Surg 85:172–178

    Article  Google Scholar 

  17. Rajasinghe HA, McElhinney DB, Reddy VM, Mora BN, Hanley FL (1997) Long-term follow-up of truncus arteriosus repaired in infancy: a twenty-year experience. J Thorac Cardiovasc Surg 113:869–878

    Article  CAS  Google Scholar 

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Correspondence to Woong-han Kim.

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Kang, Y., Kwak, J.G., Min, J. et al. Twenty-Year Experience with Truncus Arteriosus Repair: Changes in Risk Factors in the Current Era. Pediatr Cardiol 42, 123–130 (2021). https://doi.org/10.1007/s00246-020-02461-5

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