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Silk Vista Baby flow diverter stent for ruptured intracranial aneurysms: a retrospective observational study

  • Interventional Neuroradiology
  • Published:
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Abstract

Purpose

Flow diversion changed the approach to complex intracranial aneurysms, leading to a widespread use and a rapid technological evolution. Indeed, indications continued to expand, including ruptured intracranial aneurysms in selected cases. Recently, new devices have been designed specifically to target smaller vessels. Therefore, we conducted a multicenter study to evaluate clinical outcome, complications, and occlusion rate of patients with ruptured aneurysms treated with new generation low profile Silk Vista Baby (SVB) flow diverter stent (FD).

Methods

We performed a retrospective observational study on consecutive patients who underwent treatment with SVB for ruptured aneurysms at 12 Italian centers. Primary end point was favorable clinical outcome rate, defined as modified ranking score (mRS) of 0–2 at the 3 months. Secondary outcomes were complication rate, aneurysm re-rupture, and complete aneurysm occlusion at last radiological follow-up.

Results

Twenty-five patients were included; at 3 months’ follow-up, 19 patients (79.1%) had favorable clinical outcome (mRS 0–2). Three patients (12.5%) died during follow-up. In-stent thrombosis occurred in two cases (8.3%), managed with glycoprotein IIb/IIIA and intra-stent angioplasty, without clinical consequences. In 18 (85.7%) patients, complete occlusion at 3 months was demonstrated. No rebleeding occurred during follow-up. Presentation with unfavorable World Federation of Neurosurgical Societies grading system (WFNS) and posterior circulation location were both significantly correlated with unfavorable clinical outcome (p = 0.005 and p = 0.02).

Conclusions

Our data suggests that low profile FD treatment of ruptured intracranial aneurysms located distally of the circle of Willis is feasible. New generation low profile FD may represent an alternative option in carefully selected cases.

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Data availability

The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.

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Funding

The authors did not receive support from any organization for the submitted work.

Author information

Authors and Affiliations

  1. Department of Neuroscience, Azienda Ospedaliero Universitaria Città Della Salute E Della Scienza Di Torino, Neuroradiological Unit, University of Turin, Turin, Italy

    Riccardo Russo & Mauro Bergui

  2. Department of Interventional Radiology and Neuroradiology, S. Giovanni Bosco Hospital, Turin, Italy

    Andrea Boghi

  3. ASST Sette Laghi, Neuroradiology, Varese, Italy

    Andrea Giorgianni & Stefano Molinaro

  4. Pisana University Hospital, Pisa, Italy

    Guido Andrea Lazzarotti

  5. Interventional Neuroradiology, Fondazione PTV Policlinico Tor Vergata, Rome, Italy

    Alessio Bozzi & Fabrizio Chegai

  6. Azienda Ospedaliero Universitaria Di Ferrara Arcispedale Sant Anna, Neuroradiology, Ferrara, Emilia-Romagna, Italy

    Andrea Saletti

  7. ASST Papa Giovanni XXIII Bergamo, Lombardia, Italy

    Gabriele Gallizioli

  8. Azienda Sanitaria Universitaria Friuli Centrale, Interventional Radiology, Udine, Italy

    Vladimir Gavrilovic

  9. Interventional Neuroradiology, Vita-Salute San Raffaele University Hospital, Milan, Italy

    Caterina Michelozzi

  10. Azienda Sanitaria Alto Adige, Regional Hospital of Bolzano, Radiology Unit, Bolzano, Italy

    Benedetto Petralia & Tommaso Gorgatti

  11. Department of Radiology, University of Verona, Verona, Italy

    Francesco Lorenzo Gatti

  12. Department of Radiology, Azienda Ospedaliera SS Antonio E Biagio E C. Arrigo, Alessandria, Italy

    Ivan Gallesio

  13. Department of Diagnostic and Interventional Neuroradiology, Azienda Ospedaliera Cannizzaro, Catania, Italy

    Concetto Cristaudo & Marco Angelo Politi

Authors
  1. Riccardo Russo
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  2. Andrea Boghi
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  3. Andrea Giorgianni
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  4. Guido Andrea Lazzarotti
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  5. Alessio Bozzi
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  6. Fabrizio Chegai
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  7. Andrea Saletti
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  8. Gabriele Gallizioli
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  9. Vladimir Gavrilovic
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  10. Caterina Michelozzi
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  11. Benedetto Petralia
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  12. Francesco Lorenzo Gatti
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  13. Tommaso Gorgatti
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  14. Ivan Gallesio
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  15. Concetto Cristaudo
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  16. Marco Angelo Politi
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  17. Stefano Molinaro
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  18. Mauro Bergui
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Corresponding author

Correspondence to Riccardo Russo.

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Conflicts of interest/competing interests

The authors have no relevant financial or non-financial interests to disclose.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Consent to participate/consent for publication

Not required considering the retrospective nature of the study according to the local institutional review board of the coordinating center (no. 0010755–2022).

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Russo, R., Boghi, A., Giorgianni, A. et al. Silk Vista Baby flow diverter stent for ruptured intracranial aneurysms: a retrospective observational study. Neuroradiology 64, 2031–2037 (2022). https://doi.org/10.1007/s00234-022-03003-x

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  • DOI: https://doi.org/10.1007/s00234-022-03003-x

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