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Open-cell stent-assisted coiling for the treatment of paraclinoid aneurysms: traditional endovascular treatment is still not out of date

  • Interventional Neuroradiology
  • Published:
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Abstract

Purpose

Before we enter the era of flow diverter stents (FDS), the standard stent-assisted coiling technique is a well-established treatment option for routine paraclinoid aneurysms. We assess the clinical safety and efficacy of stent-assisted coiling with open-cell stent in the treatment of paraclinoid aneurysms and evaluate the association between clinical factors and follow-up aneurysm occlusion.

Methods

The clinical and radiographic data of 110 consecutive patients with 122 paraclinoid aneurysms treated with open-cell stent between April 2015 and April 2019 were analyzed retrospectively at our center. We assessed the immediate and progressive occlusion rates, complications, and clinical outcome. Multivariate analysis was performed to investigate the risk factors of angiographic incomplete occlusion.

Results

Among 110 patients, stent-assisted coiling was successfully performed in all cases. Four (3.6%) thromboembolic events were reported during the procedure, which resulted in transient morbidity. Immediate angiography demonstrated complete occlusion in 64 (52.5%) aneurysms and no occlusion of ophthalmic artery. Angiographic follow-up at 6 months demonstrated an increase in the complete occlusion rate to 92.9%. No delayed in-stent stenosis was observed, and three aneurysms recurred. Clinical follow-up was completed in 102 patients (92.7%), and favorable outcomes were achieved in 101 (99%) patients at 6 months. Multivariate analysis showed that aneurysm size (p < 0.001) was associated with incomplete aneurysm occlusion at follow-up.

Conclusion

Stent-assisted coil embolization with open-cell stents is safe and effective for the treatment of paraclinoid aneurysms and provides progressive occlusion without significant in-stent stenosis events.

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No funding was received for conducting this study.

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Author notes

  1. Heng Ni and Lin-Bo Zhao contributed equally to this work.

Authors and Affiliations

  1. Department of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, Jiangsu, China

    Heng Ni, Lin-Bo Zhao, Sheng Liu, Zhen-Yu Jia, Yue-Zhou Cao & Hai-Bin Shi

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  1. Heng Ni
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Contributions

Heng Ni and Lin-Bo Zhao analyzed the data and drafted the manuscript;

Sheng Liu, Zhen-Yu Jia, and Yue-Zhou Cao helped perform the analysis with constructive discussions; Hai-Bin Shi generated the conception, and final approval the version to be submitted.

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Correspondence to Hai-Bin Shi.

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Ni, H., Zhao, LB., Liu, S. et al. Open-cell stent-assisted coiling for the treatment of paraclinoid aneurysms: traditional endovascular treatment is still not out of date. Neuroradiology 63, 1521–1530 (2021). https://doi.org/10.1007/s00234-021-02679-x

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