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Molecularly imprinted polymer nanoparticles-based electrochemical sensor for determination of diazinon pesticide in well water and apple fruit samples

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Abstract

In this research, an electrochemical sensor based on molecularly imprinted polymer (MIP) nanoparticles for selective and sensitive determination of diazinon (DZN) pesticides was developed. The nanoparticles of diazinon imprinted polymer were synthesized by suspension polymerization and then used for modification of carbon paste electrode (CPE) composition in order to prepare the sensor. Cyclic voltammetry (CV) and square wave voltammetry (SWV) methods were applied for electrochemical measurements. The obtained results showed that the carbon paste electrode modified by MIP nanoparticles (nano-MIP-CP) has much higher adsorption ability for diazinon than the CPE based non-imprinted polymer nanoparticles (nano-NIP-CP). Under optimized extraction and analysis conditions, the proposed sensor exhibited excellent sensitivity (95.08 μA L μmol−1) for diazinon with two linear ranges of 2.5 × 10−9 to 1.0 × 10−7 mol L−1 (R 2 = 0.9971) and 1.0 × 10−7 to 2.0 × 10−6 mol L−1 (R 2 = 0.9832) and also a detection limit of 7.9 × 10−10 mol.L−1. The sensor was successfully applied for determination of diaznon in well water and apple fruit samples with recovery values in the range of 92.53–100.86 %.

Procedure for preparation of electrochemical sensor based on MIP nanoparticles for determination of diazinon

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Acknowledgments

The authors gratefully acknowledge the support of this work by the Electroanalytical Chemistry Research Centre of Iran University of Science and Technology and the Pharmaceutical Research Center of Mashhad University of Medical Sciences.

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Authors and Affiliations

  1. Research Laboratory of Real Samples Analysis, Faculty of Chemistry, Iran University of Science and Technology, Tehran, 1684613114, Iran

    Ali Motaharian & Mohammad Reza Milani Hosseini

  2. Pharmaceutical Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

    Fatemeh Motaharian, Khalil Abnous & Mohammad Hassanzadeh-Khayyat

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  1. Ali Motaharian
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  2. Fatemeh Motaharian
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  3. Khalil Abnous
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  4. Mohammad Reza Milani Hosseini
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Correspondence to Ali Motaharian.

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Motaharian, A., Motaharian, F., Abnous, K. et al. Molecularly imprinted polymer nanoparticles-based electrochemical sensor for determination of diazinon pesticide in well water and apple fruit samples. Anal Bioanal Chem 408, 6769–6779 (2016). https://doi.org/10.1007/s00216-016-9802-7

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  • DOI: https://doi.org/10.1007/s00216-016-9802-7

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