Skip to main content
SpringerLink
Log in

An innovative arrangement for in-vial membrane-assisted liquid-liquid microextraction: application to the determination of esters of phthalic acid in alcoholic beverages by gas chromatography-mass spectrometry

  • Note
  • Published:
Analytical and Bioanalytical Chemistry Aims and scope Submit manuscript

Abstract

A new arrangement for membrane-assisted liquid-liquid microextraction is presented. The extracting organic solvent was placed into a chromatographic microvial, compatible with the chromatograph autosampler, whose septum was replaced by a disc of porous hydrophobic membrane. This extraction device was completely immersed into the analytical sample contained in a cylindrical container subjected to rotary and basculant movement. Then, the extraction of analytes took place from the sample to the organic solvent contained in the vial through the membrane. Esters of the phthalic acid have been selected as model analytes to determine the performance characteristics of the extraction system. The limits of detection, limits of quantification and relative standard deviations (%) were in the range 0.1–0.4, 0.3–1 and 4–7, respectively. Esters of phthalic acid have been successfully analysed in alcoholic beverages. The main operational advantages of this arrangement consisted of minimal required handling, minimal risk of cross contamination and its simplicity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Pedersen-Bjergaard S, Rasmussen KE (2008) J Chromatogr A 1184:132–142

    Article  CAS  Google Scholar 

  2. Moeder M, Bauer C, Popp P, van Pinxteren M, Reemtsma T (2012) Anal Bioanal Chem 403:1731–1741

    Article  CAS  Google Scholar 

  3. Jiang X, Lee HK (2004) Anal Chem 76:5591–5596

    Article  CAS  Google Scholar 

  4. Yu C, Liu Q, Lan L, Hu B (2008) J Chromatogr A 1188:124–131

    Article  CAS  Google Scholar 

  5. March JG, Moukhchan F, Cerdà V (2011) Anal Chim Acta 685:132–137

    Article  CAS  Google Scholar 

  6. Alcudia-León MC, Lucena R, Cárdenas S, Valcárcel M (2011) J Chromatogr A 1218:869–874

    Article  Google Scholar 

  7. Huang G, Li HF, Zhang BT, Ma Y, Lin JM (2012) Talanta 100:64–70

    Article  CAS  Google Scholar 

  8. Carrillo JD, Salazar C, Moreta C, Tena MT (2007) J Chromatogr A 1164:248–261

    Article  CAS  Google Scholar 

  9. Cinelli G, Avino P, Notardonato I, Centola A, Russo MV (2013) Anal Chim Acta 769:72–78

    Article  CAS  Google Scholar 

Download references

Acknowledgments

Grant CTQ2013-47461-R (‘Ministerio de Economía y Competitividad’ Spanish Government) is acknowledged. Informatics assistance from D. Moreno is strongly appreciated.

Author information

Authors and Affiliations

  1. Department of Chemistry, University of Balearic Islands, Carretera de Valldemossa, Km 7,5, 07122, Palma de Mallorca, Spain

    Juan Gabriel March & Victor Cerdà

Authors
  1. Juan Gabriel March
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Victor Cerdà
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Juan Gabriel March.

Electronic supplementary material

Below is the link to the electronic supplementary material.

ESM 1

(PDF 248 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

March, J.G., Cerdà, V. An innovative arrangement for in-vial membrane-assisted liquid-liquid microextraction: application to the determination of esters of phthalic acid in alcoholic beverages by gas chromatography-mass spectrometry. Anal Bioanal Chem 407, 4213–4217 (2015). https://doi.org/10.1007/s00216-015-8646-x

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00216-015-8646-x

Keywords

Search

Navigation