Skip to main content
SpringerLink
Log in

Omega-3 consumption and sudden unexpected death in schizophrenia: a “fish” a day keeps heart disease away

  • Letter to the Editor
  • Published:
Psychopharmacology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Xu F, Fan W, Wang W, Tang W, Yang F, Zhang Y, Cai J, Song L, Zhang C (2019) Effects of omega-3 fatty acids on metabolic syndrome in patients with schizophrenia: a 12-week randomized placebo-controlled trial. Psychopharmacology. https://doi.org/10.1007/s00213-018-5136-9

  • Pennington M, McCrone P (2017) The cost of relapse in schizophrenia. Pharmacoeconomics 35:921–936

    Article  PubMed  Google Scholar 

  • Li KJ, Greenstein AP, Delisi LE (2018) Sudden death in schizophrenia. Curr Opin Psychiatry 31:169–175

    Article  PubMed  Google Scholar 

  • Scorza FA, Cysneiros RM, Terra VC, Scorza CA, Cavalheiro EA, Ribeiro MO, Gattaz WF (2009 Oct) Omega-3 consumption and sudden cardiac death in schizophrenia. Prostaglandins Leukot Essent Fatty Acids 81(4):241–245

    Article  CAS  PubMed  Google Scholar 

  • Bobes J, Arango C, Aranda P, Carmena R, Garcia-Garcia M, Rejas J, on behalf of the CLAMORS Study Collaborative Group (2007) Cardiovascular and metabolic risk in outpatients with schizophrenia treated with antipsychotics: results of the CLAMORS Study. Schizophr Res 90:162–173

    Article  PubMed  Google Scholar 

  • Scorza FA, Cysneiros RM, Cavalheiro EA, Arida RM, de Albuquerque M (2007) Omega-3 fatty acids and sudden cardiac death in schizophrenia: if not a friend, at least a great colleague. Schizophr Res 94:375–376

    Article  PubMed  Google Scholar 

  • Auquier P, Lancon C, Rouillon F, Lader M, Holmes C (2006) Mortality in schizophrenia. Pharmacoepidemiol Drug Saf 15:873–879

    Article  PubMed  Google Scholar 

  • Ruschena D, Mullen PE, Burgess P, Cordner SM, Barry-Walsh J, Drummer OH, Palmer S, Browne C, Wallace C (1998) Sudden death in psychiatric patients. Br J Psychiatry 172:331–336

    Article  CAS  PubMed  Google Scholar 

  • Scorza FA, Mari JJ, Bressan RA (2006) Sudden cardiac death in schizophrenia: should the psychiatrist pay more attention? Rev Bras Psiquiatr 28:339

    Article  PubMed  Google Scholar 

  • Glassman AH (2005) Schizophrenia, antipsychotic drugs, and cardiovascular disease. J Clin Psychiatry 66:5–10

    Article  PubMed  Google Scholar 

  • Straus SM, Bleumink GS, Dieleman JP, van der Lei J, Jong GW, Kingma JH, Sturkenboom MC, Stricker BH (2004) Antipsychotics and the risk of sudden cardiac death. Arch Intern Med 164:1293–1297

    Article  PubMed  Google Scholar 

  • Zarate CA, Patel J (2001) Sudden cardiac death and antipsychotic drugs: do we know enough? Arch Gen Psychiatry 58:1168–1171

    Article  CAS  PubMed  Google Scholar 

  • Pansani AP, Colugnati DB, Scorza CA, de Almeida AC, Cavalheiro EA, Scorza FA (2016) Furthering our understanding of SUDEP: the role of animal models. Expert Rev Neurother 16(5):561–572

    Article  CAS  PubMed  Google Scholar 

  • Nejm MB, Haidar AA, Hirata AE, Arida RM, Naffah-Mazacoratti Mda G, Cavalheiro EA, Cysneiros RM, Scorza FA (2012) Interleukin-6 bares a dark side in sudden unexpected death in epilepsy. Epilepsy Behav 24:285–286

    Article  PubMed  Google Scholar 

  • Nejm MB, Haidar AA, Hirata AE, Oyama LM, de Almeida AG, Cysneiros RM, Cavalheiro EA, Scorza CA, Scorza FA (2017) Fish oil supplementation reduces heart levels of interleukin-6 in rats with chronic inflammation due to epilepsy. Front Neurol 8:263

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Disciplina de Neurociência, Universidade Federal de São Paulo/Escola Paulista de Medicina (UNIFESP/EPM), Rua Pedro de Toledo, 669 – 1st floor, São Paulo, SP, 04039-032, Brazil

    Fulvio A. Scorza, Carla A. Scorza & Leandro Freitas

  2. Programa de Estudos Pós-Graduado em Fonoaudiologia, Pontifícia Universidade Católica de São Paulo (PUC-SP), São Paulo, Brazil

    Ana C. Fiorini

  3. Departamento de Fonoaudiologia, Escola Paulista de Medicina/Universidade Federal de São Paulo (EPM/UNIFESP), São Paulo, Brazil

    Ana C. Fiorini

  4. Departamento de Psiquiatria, Universidade Federal de São Paulo/Escola Paulista de Medicina (UNIFESP/EPM), São Paulo, Brazil

    Jair de Jesus Mari

  5. Krankenanstalt Rudolfstiftung, Messerli Institute, Veterinary University of Vienna, Vienna, Austria

    Josef Finsterer

Authors
  1. Fulvio A. Scorza
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Carla A. Scorza
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Ana C. Fiorini
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Jair de Jesus Mari
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Leandro Freitas
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Josef Finsterer
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

All wrote and reviewed the final version of the article.

Corresponding author

Correspondence to Fulvio A. Scorza.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Scorza, F.A., Scorza, C.A., Fiorini, A.C. et al. Omega-3 consumption and sudden unexpected death in schizophrenia: a “fish” a day keeps heart disease away. Psychopharmacology 236, 2285–2286 (2019). https://doi.org/10.1007/s00213-019-05201-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00213-019-05201-7

Search

Navigation