Skip to main content

Advertisement

Log in

The economic burden of fracture patients with osteoporosis in western China

  • Original Article
  • Published:
Osteoporosis International Aims and scope Submit manuscript

Abstract

Summary

To study the cost of osteoporotic fracture in China, we performed a prospective study and compared the costs of the disease in referral patients with fractures in three of the most common sites. Our results indicated that the economic burden of osteoporotic fracture to both Chinese patients and the nation is heavy.

Introduction

This paper aims to study the cost of osteoporotic fracture in China and thus to provide essential information about the burden of this disease to individuals and society.

Methods

This prospective observational data collection study assessed the cost related to hip, vertebral, and wrist fracture 1 year after the fracture based on a patient sample consisting of 938 men and women. Information was collected using patient records, registry sources, and patient interviews. Both direct medical, direct non-medical, and indirect non-medical costs were considered.

Results

The annual total costs were highest in hip fracture patients (renminbi, RMB 27,283 or USD 4,330, with confidence interval (RMB 25715, 28851)), followed by patients with vertebral fracture (RMB 21,474 or USD 3,409, with confidence interval (RMB 20082, 22866)) and wrist fracture (RMB 8,828 or USD 1,401, with confidence interval (RMB 7829, 9827)). The direct medical care costs averaged approximately RMB 17,007 per year per patient, of which inpatient costs, drugs, and investigations accounted for the majority of the costs. Nonmedical direct costs were much less compared to direct healthcare costs and averaged approximately RMB 1,846.

Conclusion

These results indicate that the economic burden of osteoporotic fracture to both Chinese patients and China was heavy, and the proportion of the costs in China demonstrated many similar features and some significant differences compared to other countries.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Looker AC, Orwoll ES, Johnston CC Jr, Lindsay RL, Wahner HW, Dunn WL, Calvo MS, Harris TB, Heyse SP (1997) Prevalence of low femoral bone density in older U.S. adults from NHANES III. J Bone Miner Res 12:1761–1768

    Article  CAS  PubMed  Google Scholar 

  2. Kanis JA, Johnell O, Oden A, Jonsson B, De Laet C, Dawson A (2000) Risk of hip fracture according to the World Health Organization criteria for osteopenia and osteoporosis. Bone 27:585–590

    Article  CAS  PubMed  Google Scholar 

  3. Ballard PA, Purdie DW, Langton CM, Steel SA, Mussurakis S (1998) Prevalence of osteoporosis and related risk factors in UK women in the seventh decade: osteoporosis case finding by clinical referral criteria or predictive model? Osteoporos Int 8:535–539

    Article  CAS  PubMed  Google Scholar 

  4. Wang Y, Tao Y, Hyman ME, Li J, Chen Y (2009) Osteoporosis in China. Osteoporos Int 20:1651–1662

    Article  CAS  PubMed  Google Scholar 

  5. Pike C, Birnbaum HG, Schiller M, Sharma H, Burge R, Edgell ET (2010) Direct and indirect costs of non-vertebral fracture patients with osteoporosis in the US. Pharmacoeconomics 28:395–409

    Article  PubMed  Google Scholar 

  6. Guillemin F, Martinez L, Calvert M et al (2013) Fear of falling, fracture history, and comorbidities are associated with health-related quality of life among European and US women with osteoporosis in a large international study. Osteoporos Int 24:3001–3010

    Article  CAS  PubMed  Google Scholar 

  7. Harvey NC, Matthews P, Collins R, Cooper C, Group UKBMA (2013) Osteoporosis epidemiology in UK Biobank: a unique opportunity for international researchers. Osteoporos Int 24:2903–2905

    Article  Google Scholar 

  8. Borgstrom F, Zethraeus N, Johnell O et al (2006) Costs and quality of life associated with osteoporosis-related fractures in Sweden. Osteoporos Int 17:637–650

    Article  PubMed  Google Scholar 

  9. Haussler B, Gothe H, Gol D, Glaeske G, Pientka L, Felsenberg D (2007) Epidemiology, treatment and costs of osteoporosis in Germany—the BoneEVA Study. Osteoporos Int 18:77–84

    Article  CAS  PubMed  Google Scholar 

  10. Tarride JE, Hopkins RB, Leslie WD, Morin S, Adachi JD, Papaioannou A, Bessette L, Brown JP, Goeree R (2012) The burden of illness of osteoporosis in Canada. Osteoporos Int 23:2591–2600

    Article  PubMed Central  PubMed  Google Scholar 

  11. Luo LZ, Xu L (2005) Study on direct economic-burden and its risk factors of osteoporotic hip fracture. Zhonghua Liu Xing Bing Xue Za Zhi 26:669–672

    PubMed  Google Scholar 

  12. Dai K, Zhang Q, Fan T, Sen SS (2007) Estimation of resource utilization associated with osteoporotic hip fracture and level of post-acute care in China. Curr Med Res Opin 23:2937–2943

    Article  PubMed  Google Scholar 

  13. Ma J, Guo H, Yang X (2009) Epidemiology of primary osteoporosis. Chin Gen Pract 12:1744–1746

    Google Scholar 

  14. Borgstrom F, Lekander I, Ivergard M et al (2013) The International Costs and Utilities Related to Osteoporotic Fractures Study (ICUROS)—quality of life during the first 4 months after fracture. Osteoporos Int 24:811–823

    Article  CAS  PubMed  Google Scholar 

  15. Chen Z, Maricic M, Aragaki AK, Mouton C, Arendell L, Lopez AM, Bassford T, Chlebowski RT (2009) Fracture risk increases after diagnosis of breast or other cancers in postmenopausal women: results from the Women’s Health Initiative. Osteoporos Int 20:527–536

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  16. Abelson A (2008) A review of Paget's disease of bone with a focus on the efficacy and safety of zoledronic acid 5 mg. Curr Med Res Opin 24:695–705

    Article  CAS  PubMed  Google Scholar 

  17. Strom O, Borgstrom F, Zethraeus N et al (2008) Long-term cost and effect on quality of life of osteoporosis-related fractures in Sweden. Acta Orthop 79:269–280

    Article  PubMed  Google Scholar 

  18. Wang H, Li C, Xiang Q, Xiong H, Zhou Y (2012) Epidemiology of spinal fractures among the elderly in Chongqing, China. Injury 43:2109–2116

    Article  PubMed  Google Scholar 

  19. Zhu H, Zhang Y, Zhu X, Chen X, Yang J, Zhang X, Cheng Q (2003) Osteoporotic fracture and change of its iccidence in the elderly during 8 years. Geriatr Health Care 9:89–92

    Google Scholar 

  20. Nevitt MC, Xu L, Zhang Y, Lui LY, Yu W, Lane NE, Qin M, Hochberg MC, Cummings SR, Felson DT (2002) Very low prevalence of hip osteoarthritis among Chinese elderly in Beijing, China, compared with whites in the United States: the Beijing osteoarthritis study. Arthritis Rheum 46:1773–1779

    Article  PubMed  Google Scholar 

  21. Shang W, Yu W, Xu L, Lin Q, Tian JP (2005) Correlation between prevalent and incident osteoporotic vertebral fractures in Beijing male elderly. Zhonghua Yi Xue Za Zhi 85:84–87

    PubMed  Google Scholar 

  22. Bow CH, Cheung E, Cheung CL et al (2012) Ethnic difference of clinical vertebral fracture risk. Osteoporos Int 23:879–885

    Article  CAS  PubMed Central  PubMed  Google Scholar 

Download references

Acknowledgments

This work was supported by grants obtained from the National Natural Science Fund of China (no. 30900471) and Sichuan Science and Technology Support Program (no. 2013SZ0003).

Conflicts of interest

None.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Z. Hong.

Electronic supplementary material

Below is the link to the electronic supplementary material.

ESM 1

(DOC 53 kb)

ESM 2

(DOC 38 kb)

ESM 3

(DOC 63 kb)

Rights and permissions

Reprints and permissions

About this article

Cite this article

Qu, B., Ma, Y., Yan, M. et al. The economic burden of fracture patients with osteoporosis in western China. Osteoporos Int 25, 1853–1860 (2014). https://doi.org/10.1007/s00198-014-2699-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00198-014-2699-0

Keywords

Navigation