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Self-assessment of treatment compliance with antimuscarinic drugs and lower urinary tract condition among women with urinary incontinence

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Abstract

Aim

Our aim was to determine the efficiency of the Medication Compliance Self-Report Inventory (MASRI) in self-reporting antimuscarinic drug treatment compliance among women with urinary incontinence (UI).

Materials and methods

The study assessed 347 women aged 18–65 (averaging 49.7) years with more than one urinary incontinence (UI) episode per day. Treatment compliance was tested at the beginning and at weeks 4, 8, and 12 using the MASRI, the Brief Medication Questionnaire (BMQ), and visual pill counts. The MASRI’s constructive, concurrent, and discriminate validity was studied in comparison with an external standard that uses the chi-square and Spearman coefficient. Receiver operating characteristic (ROC) analysis was performed to identify optimum MASRI cutoffs that would predict noncompliance. Furthermore, the functional condition of the lower urinary tract was tested using voiding diaries, uroflowmetry, and cystometry.

Result

The correlation between the percentage of noncompliant women according to the MASRI, and individuals with a belief barrier with respect to the BMQ screen was r = 0.81 (p ≤0.05), r = 0.84 (p ≤0.05), and r = 0.79 (p ≤0.05). The correlation between the percentage of noncompliant women according to the MASRI and of women who missed >20% of their doses according to the Regimen Screen of the BMQ was r = 0.79, p ≤0.05, r = 0.82, p ≤0.01, r = 0.77, and p ≤0.05 at the control points. Finally, the percentage of noncompliant patients who self-reported correctly according to the MASRI data compared with the BMQ was 95.6%, 95.7%, and 96.6% at the control points.

Conclusion

The MASRI entails acceptable validity for accurately predicting treatment compliance with antimuscarinic drugs among women who have had UI for >3 months.

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Author notes

  1. All authors contributed equally to the creation of the article.

Authors and Affiliations

  1. Department of Social and Psychologikal Science, Far Eastern Federal University, Ayax, 10, F733, Vladivostok, Primorsky Region, Russian Federation

    Kirill Kosilov, Irina Kuzina & Alexandra Lobodenko

  2. Department of Urology, City Polyclinic № 3, Lugivaya 50, Vladivostok, Russian Federation

    Sergey Loparev

  3. Department of Theory and Methods of Adaptive Physical Education, Far Eastern Federal University, Ayax, 10, S1, Vladivostok, Russian Federation

    Olga Shakirova & Natalya Zhuravskaya

Authors
  1. Kirill Kosilov
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  2. Sergey Loparev
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  3. Irina Kuzina
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  4. Olga Shakirova
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  5. Natalya Zhuravskaya
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  6. Alexandra Lobodenko
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Correspondence to Kirill Kosilov.

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The leading organization:

1. Far Eastern Federal University, Ajax 10, corp.F, office 733, Vladivostok, Primorsky region, Russian Federation

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Kosilov, K., Loparev, S., Kuzina, I. et al. Self-assessment of treatment compliance with antimuscarinic drugs and lower urinary tract condition among women with urinary incontinence. Int Urogynecol J 28, 1663–1669 (2017). https://doi.org/10.1007/s00192-017-3333-4

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  • DOI: https://doi.org/10.1007/s00192-017-3333-4

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