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A first reported case of clear cell carcinoma associated with delayed extrusion of midurethral tape

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Abstract

We present the first reported case of clear cell carcinoma associated with a midurethral tape (MUT), the possible hypotheses and the management pitfalls we encountered. We report a 58-year-old woman who presented with symptoms of urinary tract infection and acute retention of urine associated with vaginal tape exposure 10 years after placement of an inside–out transobturator tape. She subsequently had a partial transobturator tape excision and a diagnostic cystoscopy, which revealed inflammatory changes within the urethra. Postoperatively, her symptoms persisted and the vaginal epithelium healed poorly. A biopsy of the friable tissue reported clear cell carcinoma. Imaging showed a locally invasive periurethral mass and bony and lymphatic metastases. This was treated with palliative radiation therapy. She was still receiving palliative care 5 months after the initial surgery.

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Authors and Affiliations

  1. Department of Obstetrics and Gynaecology, National University Health System, 1E Kent Ridge Road, Singapore, 119228, Singapore

    Harvard Zhenjia Lin, Jeffrey Jen Hui Low & Roy Kwok Weng Ng

  2. Department of Urology, National University Health System, Singapore, Singapore

    Fiona Meiwen Wu

  3. Department of Pathology, National University Health System, Singapore, Singapore

    Kotamma Venkateswaran

Authors
  1. Harvard Zhenjia Lin
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  2. Fiona Meiwen Wu
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  3. Jeffrey Jen Hui Low
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  4. Kotamma Venkateswaran
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  5. Roy Kwok Weng Ng
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Correspondence to Harvard Zhenjia Lin.

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Brief summary

A first case of a delayed transobturator tape mesh extrusion associated with clear cell carcinoma of the periurethral tissue. Presentation, diagnosis, management, and possible hypotheses are discussed

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Lin, H.Z., Wu, F.M., Low, J.J.H. et al. A first reported case of clear cell carcinoma associated with delayed extrusion of midurethral tape. Int Urogynecol J 27, 377–380 (2016). https://doi.org/10.1007/s00192-015-2876-5

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  • DOI: https://doi.org/10.1007/s00192-015-2876-5

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