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Tissue-Specific Antioxidative Responses and Cadmium Accumulation in Silurus meridionalis Under Chronic Waterborne Cadmium Exposure

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Abstract

In this study, the oxidative damage, antioxidative responses and cadmium (Cd) accumulation in juvenile Silurus meridionalis were studied, after S. meridionalis were exposed to 0 (control), 62.5, 125, 250 and 500 µg Cd/L for 56 days. Cd accumulation, malondialdehyde, superoxide dismutase (SOD), catalase, glutathione (GSH) and total antioxidant capacity (T-AOC) were determined in gill, liver, kidney and intestine tissues. The results showed that the Cd accumulation in S. meridionalis was dose-dependent and tissue-specific, with the highest Cd content in the kidney, followed by the liver, gill, and intestine. Waterborne Cd stress in S. meridionalis was expressed as tissue-specific oxidative damage and antioxidant responses in gill, liver, kidney and intestine tissues. Waterborne Cd exposure induced the most significant oxidative damage in the gill, followed by the liver and kidney, while the intestine showed no sensitivity to waterborne Cd exposure. The antioxidants, such as SOD in the liver, kidney and intestine, as well as T-AOC and GSH in the gill, liver and kidney, were sensitive to waterborne Cd exposure.

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References

  • Asagba SO, Eriyamremu GE, Igberaese ME (2008) Bioaccumulation of cadmium and its biochemical effect on selected tissues of the catfish (Clarias gariepinus). Fish Physiol Biochem 34(1):61–69

    Article  CAS  Google Scholar 

  • Bradford M (1976) A rapid and sensitive assay of protein utilizing the principle of dye binding. Anal Biochem 72:248–254

    Article  CAS  Google Scholar 

  • Bustamante P, Bocher P, Chérel Y, Miramand P, Caurant F (2003) Distribution of trace elements in the tissues of benthic and pelagic fish from the Kerguelen Islands. Sci Total Environ 313(1–3):25–39

    Article  CAS  Google Scholar 

  • Cao L, Huang W, Shan X, Ye Z, Dou S (2012) Tissue-specific accumulation of cadmium and its effects on antioxidative responses in Japanese flounder juveniles. Environ Toxicol Pharmacol 33(1):16–25

    Article  CAS  Google Scholar 

  • Chen Y (2012) The downstream of Zunyi molybdenum and nickel mine water pollution and biological toxicity studies. Sci Technol Innov Appl 9:121–122

    Google Scholar 

  • Chen QL, Gong Y, Luo Z, Zheng JL, Zhu QL (2013) Differential effect of waterborne cadmium exposure on lipid metabolism in liver and muscle of yellow catfish Pelteobagrus fulvidraco. Aquat Toxicol 142–143:380–386

    Article  Google Scholar 

  • Dabas A, Nagpure NS, Kumar R, Kushwaha B, Kumar P, Lakra WS (2012) Assessment of tissue-specific effect of cadmium on antioxidant defense system and lipid peroxidation in freshwater murrel, Channa punctatus. Fish Physiol Biochem 38(2):469–482

    Article  CAS  Google Scholar 

  • Dang F, Wang WX (2009) Assessment of tissue-specific accumulation and effects of cadmium in a marine fish fed contaminated commercially produced diet. Aquat Toxicol 95(3):248–255

    Article  CAS  Google Scholar 

  • De Boeck G, Meeus W, De Coen W, Blust R (2004) Tissue-specific Cu bioaccumulation patterns and differences in sensitivity to waterborne Cu in three freshwater fish: rainbow trout (Oncorhynchus mykiss), common carp (Cyprinus carpio), and gibel carp (Carassius auratus gibelio). Aquat Toxicol 70(3):179–188

    Article  Google Scholar 

  • Deng DF (2012) Ecophysiological effects of the water-borne lead (Pb) concentrations on Chinese sucker (Myxocyprinus asiaticus). Dissertation, Southwest University, Chongqing, China

  • Duman F, Kar M (2013) Evaluation of effects of exposure conditions on the biological responses of Gammarus pulex exposed to cadmium. Int J Environ Sci Technol 12(2):437–444

    Article  Google Scholar 

  • Ellman GL (1959) Tissue sulfhydryl groups. Arch Biochem Biophys 82(1):70–77

    Article  CAS  Google Scholar 

  • Javed M (2012) Tissue-specific Bio-accumulation of metals in fish during chronic waterborne and dietary exposures. Pak Vet J 32(4):567–570

    CAS  Google Scholar 

  • Jia X, Zhang H, Liu X (2011) Low levels of cadmium exposure induce DNA damage and oxidative stress in the liver of Oujiang colored common carp Cyprinus carpio var. color. Fish Physiol Biochem 37(1):97–103

    Article  CAS  Google Scholar 

  • Jia JT, Zhai SW, Que BG (2012) Effects of different level of dietary Cd on antioxidant capacity of hepatopancreasto tilapia (Oreochromis niloticus). J Agric 2(11):52–56

    Google Scholar 

  • Kim SG, Jee JH, Kang JC (2004) Cadmium accumulation and elimination in tissues of juvenile olive flounder, Paralichthys olivaceus after sub-chronic cadmium exposure. Environ Pollut 127(1):117–123

    Article  CAS  Google Scholar 

  • Li J (2016) The contents of five heavy metals in fifteen common fish species from upstream of the Yangtze River and ecotoxicological effects of the waterborne cadmium on Silurus meridionalis. Dissertation, Southwest University Chongqing, China

  • Li J, Xie XJ (2016) Heavy metal concentrations in fish species from three gorges Reservoir, China, after impoundment. Bull Environ Contamin Toxicol 96(5):616–621

    Article  CAS  Google Scholar 

  • Li J, Luo QY, Yan YL, Xie XJ (2018) The acute toxicological response of the southern catfish to water-borne cadmium. J Chongqing Normal Univ (Nat Sci) 35(1):69–75

    Google Scholar 

  • Lushchak VI (2015) Contaminant-induced oxidative stress in fish: a mechanistic approach. Fish Physiol Biochem. https://doi.org/10.1007/s10695-015-0171-5

    Google Scholar 

  • Marklund S, Marklund G (1974) Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 47(3):469–474

    Article  CAS  Google Scholar 

  • Mashroofeh A, Bakhtiari AR, Pourkazemi M, Rasouli S (2013) Bioaccumulation of Cd, Pb and Zn in the edible and inedible tissues of three sturgeon species in the Iranian coastline of the Caspian Sea. Chemosphere 90(2):573–580

    Article  CAS  Google Scholar 

  • Nunes B, Caldeira C, Pereira JL, Goncalves F, Correia AT (2015) Perturbations in ROS-related processes of the fish Gambusia holbrooki after acute and chronic exposures to the metals copper and cadmium. Environ Sci Pollut Res Int 22(5):3756–3765

    Article  CAS  Google Scholar 

  • Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95(2):351–358

    Article  CAS  Google Scholar 

  • Peng J, Wang DY, Xu CM, Chen LP, Deng F, Zhang XF (2009) Ammonium molybdate method for detecting the activities of rice catalase. Chin Agric Sci Bull 25(16):61–64

    Google Scholar 

  • Pretto A, Loro VL, Morsch VM et al (2010) Acetylcholinesterase activity, lipid peroxidation, and bioaccumulation in silver catfish (Rhamdia quelen) exposed to cadmium. Arch Environ Contam Toxicol 58(4):1008–1014

    Article  CAS  Google Scholar 

  • Pretto A, Loro VL, Baldisserotto B et al (2011) Effects of water cadmium concentrations on bioaccumulation and various oxidative stress parameters in Rhamdia quelen. Arch Environ Contam Toxicol 60(2):309–318

    Article  CAS  Google Scholar 

  • Ruas CB, Carvalho Cdos S, de Araujo HS, Espindola EL, Fernandes MN (2008) Oxidative stress biomarkers of exposure in the blood of cichlid species from a metal-contaminated river. Ecotoxicol Environ Saf 71(1):86–93

    Article  CAS  Google Scholar 

  • Sokolova IM, Lannig G (2008) Interactive effects of metal pollution and temperature on metabolism in aquatic ectotherms: implications of global climate change. Climate Res 37(2–3):181–201

    Article  Google Scholar 

  • Squadrone S, Prearo M, Brizio P et al (2013) Heavy metals distribution in muscle, liver, kidney and gill of European catfish (Silurus glanis) from Italian Rivers. Chemosphere 90(2):358–365

    Article  CAS  Google Scholar 

  • Wang X, Yang H, Liu G, Wang Q (2011) Enzyme responses and lipid peroxidation in gills and hepatopancreas of clam Mactra vereformis, following cadmium exposure. Chin J Oceanol Limnol 29(5):981–989

    Article  CAS  Google Scholar 

  • Wang SL, Xu XR, Sun YX, Liu JL, Li HB (2013) Heavy metal pollution in coastal areas of South China: a review. Mar Pollut Bull 76(1–2):7–15

    Article  CAS  Google Scholar 

  • Xie XJ (1987) The preliminary studies of age and growth of southern catfish (Silurus meridionalis) from the Jialing River. Acta Ecol Sin 7(4):359–367

    Google Scholar 

  • Yang H, Shu Y (2015) Cadmium Transporters in the Kidney and Cadmium-Induced Nephrotoxicity. Int J Mol Sci 16:1484–1494

    Article  CAS  Google Scholar 

  • Yu Y (2013) Characteristics of heavy metals pollution of fish from Three Gorges Reservoir during the Initial Impoundment. Dissertation, China Institute of Water Resources & Hydropower Research, Beijing, China

  • Zahedi S, Mirvaghefi A, Rafati M, Mehrpoosh M (2012) Cadmium accumulation and biochemical parameters in juvenile Persian sturgeon, Acipenser persicus, upon sublethal cadmium exposure. Comp Clin Pathol 22(5):805–813

    Article  Google Scholar 

  • Zhang CL, Hu JF, Wang PW, Liu GQ, Yu SF, Han HF (2004) Effects of B (a) P on T-AOC in liver of Carassius auratus. J Environ Health 21(5):325–326

    Google Scholar 

Download references

Acknowledgements

This work was supported by the Natural Science Foundation of Chongqing (No. cstc2013jjB80008), the Fundamental Research Funds for the Central Universities (No. XDJK2016C156), the Start-up Research Grant from Qinzhou University (No. 2017KYQD107) and the Research Funds from Guangxi Key Laboratory of Beibu Gulf Marine Biodiversity Conservation (No. 2018ZB03).

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Authors and Affiliations

  1. Guangxi Key Laboratory of Beibu Gulf Marine Biodiversity Conservation, Ocean College, Qinzhou University, Qinzhou, China

    Jian Li

  2. Key Laboratory of Freshwater Fish Reproduction and Development (Ministry of Education), Institute of Hydrobiology and Water Environment, School of Life Sciences, Southwest University, Chongqing, China

    Jian Li, Yulian Yan & Xiaojun Xie

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  1. Jian Li
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  2. Yulian Yan
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  3. Xiaojun Xie
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Correspondence to Jian Li or Xiaojun Xie.

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Li, J., Yan, Y. & Xie, X. Tissue-Specific Antioxidative Responses and Cadmium Accumulation in Silurus meridionalis Under Chronic Waterborne Cadmium Exposure. Bull Environ Contam Toxicol 100, 485–491 (2018). https://doi.org/10.1007/s00128-018-2294-8

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  • DOI: https://doi.org/10.1007/s00128-018-2294-8

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