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Assessing the Effects of Amoxicillin on Antioxidant Enzyme Activities, Lipid Peroxidation and Protein Carbonyl Content in the Clam Ruditapes philippinarum and the Mussel Mytilus galloprovincialis

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Abstract

In this study, we evaluated the capability of amoxicillin (AMX)—one of the most widely used antibiotics worldwide—to induce oxidative stress in both gills and digestive gland from two bivalve species, the clam Ruditapes philippinarum and the mussel Mytilus galloprovincialis. Superoxide dismutase (SOD) and catalase (CAT) activities, as well as the lipid peroxidation levels (LPO) and protein carbonyl content (PCC), were measured in bivalves exposed to 100, 200 and 400 µg AMX/L for 1, 3 and 7 days. The results obtained demonstrated that AMX affected slightly biomarker responses of molluscs.

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Authors and Affiliations

  1. Department of Biology, University of Padova, Via Ugo Bassi 58/B, 35131, Padua, Italy

    Valerio Matozzo, Margherita Battistara, Ilaria Marisa & Valeria Bertin

  2. Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Via Marzolo 5, 35131, Padua, Italy

    Alessandro Orsetti

Authors
  1. Valerio Matozzo
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  2. Margherita Battistara
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  3. Ilaria Marisa
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  4. Valeria Bertin
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  5. Alessandro Orsetti
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Correspondence to Valerio Matozzo.

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Matozzo, V., Battistara, M., Marisa, I. et al. Assessing the Effects of Amoxicillin on Antioxidant Enzyme Activities, Lipid Peroxidation and Protein Carbonyl Content in the Clam Ruditapes philippinarum and the Mussel Mytilus galloprovincialis . Bull Environ Contam Toxicol 97, 521–527 (2016). https://doi.org/10.1007/s00128-016-1902-8

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  • DOI: https://doi.org/10.1007/s00128-016-1902-8

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