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Rapid Determination of Famoxadone and Cymoxanil in Commercial Pesticide Formulation by High Performance Liquid Chromatography Using a C18 Monolithic Rod Column

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Abstract

The extensive use of plant protection products in urban and rural pest control obliges to develop valid analytical methods for their successful and reliable quality control. An analytical procedure for the simultaneous determination of famoxadone and cymoxanil, by reversed phase high performance liquid chromatography based on the use of a monolithic C18 column has been developed and validated. The method involved the extraction of the active ingredients by sonication of the sample with acetonitrile and direct injection on a reversed phase liquid chromatographic system. The repeatability of the method expressed as relative standard deviation (%RSD), was lower than 1 % for both compounds. The limits of quantification for famoxadone and cymoxanil were 10 and 16 µg mL−1 respectively. The new method involves a considerable reduction in time for both sample preparation and analysis. The proposed analytical procedure is accurate and precise .

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Acknowledgments

This study has been supported by the International Atomic Energy Agency (IAEA), Coordinated Research Project “Quality Control of Pesticides” (contract No. 11772/RO).

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Authors and Affiliations

  1. Laboratory of Chemical Control of Pesticides, Department of Pesticides Control and Phytopharmacy, Benaki Phytopathological Institute, 8 St. Delta Street, Kifissia, 14561, Athens, Greece

    George Balayiannis & Helen Karasali

  2. Hungarian Food Safety Office, Gyáli út 2-6, Budapest, 1097, Hungary

    Arpad Ambrus

Authors
  1. George Balayiannis
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  2. Helen Karasali
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  3. Arpad Ambrus
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Correspondence to Helen Karasali.

Additional information

George Balayiannis and Helen Karasali have contributed equally to this work.

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Balayiannis, G., Karasali, H. & Ambrus, A. Rapid Determination of Famoxadone and Cymoxanil in Commercial Pesticide Formulation by High Performance Liquid Chromatography Using a C18 Monolithic Rod Column. Bull Environ Contam Toxicol 93, 775–780 (2014). https://doi.org/10.1007/s00128-014-1382-7

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  • DOI: https://doi.org/10.1007/s00128-014-1382-7

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