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Immunoglobulin subclass levels in chronic fatigue syndrome

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Abstract

The levels of immunoglobulin subclasses were determined for 46 patients meeting the original Centers for Disease Control case definition of chronic fatigue syndrome and were compared to values obtained for 50 age- and gender-matched healthy volunteer blood donor controls. The levels of immunoglobulin subclasses in these groups were further compared to a third group of additional chronic fatigue syndrome cases from whom samples had been obtained and frozen prospectively over a period of 7 years. These data do not demonstrate significant immunoglobulin subclass deficiencies in patients with chronic fatigue syndrome.

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Authors and Affiliations

  1. The Chronic Fatigue Syndrome Cooperative Research Center, USA

    Adrienne L. Bennett, Laura R. Fagioli, Richard S. Schacterle & Anthony L. Komaroff

  2. Division of General Medicine and Primary Care, Brigham and Women's Hospital, Harvard Medical School, 02115, Boston, Massachusetts

    Adrienne L. Bennett, Laura R. Fagioli, Richard S. Schacterle & Anthony L. Komaroff

  3. Lupus Center, Division of Rheumatology and Immunology, Brigham and Women's Hospital, USA

    Peter H. Schur

Authors
  1. Adrienne L. Bennett
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  2. Laura R. Fagioli
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  3. Peter H. Schur
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  4. Richard S. Schacterle
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  5. Anthony L. Komaroff
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Bennett, A.L., Fagioli, L.R., Schur, P.H. et al. Immunoglobulin subclass levels in chronic fatigue syndrome. J Clin Immunol 16, 315–320 (1996). https://doi.org/10.1007/BF01541666

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  • DOI: https://doi.org/10.1007/BF01541666

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