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Therapeutic Phytoconstituents-II

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Nanotechnology Based Delivery of Phytoconstituents and Cosmeceuticals

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Abstract

Cancer is among the most frightful disorders worldwide and an issue of major concern. Both developed and developing countries are facing enormous challenges to manage the paradigms related to cancer. Conventional treatment of cancer mainly includes surgery and chemotherapy, which takes a toll on the health and pocket of cancer patients. Chemotherapeutics generate several side effects and their efficiency is often challenged by chemo-resistance. Hence, finding a better treatment option is the need of the hour. Plants are being used in traditional medicine since time immemorial. Researchers have hence started investigating plant extracts and phytoconstituents for their anticancerous properties. The present chapter discusses a number of phytoconstituents and their role in altering one or more hallmarks of cancer in order to generate therapeutic effects in various types of cancer.

Certain bioactive agents from plants show antiproliferative, anti-inflammatory and pro-apoptotic activities against cancer cells. Herein, five major hallmarks of cancer have been elaborated and explained how plant-derived constituents can be used to target them for chemoprevention and chemotherapeutic approaches. Also, to enhance the efficacy of currently available phytochemicals, novel methods for improvement in extraction, synthesis, and administration are also briefly discussed.

Finally, major anticancer phytoconstituents are summarized with their limitations, offering a broad spectrum of possibilities for scientists in this field, to develop novel methods for therapeutic regimens in cancer.

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Acknowledgments

Author Bhavana Jodha thanks UGC for the Non-NET fellowship, and Dr. Sunita Patel acknowledges the Central University of Gujarat for providing the infrastructure and all necessary facilities.

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Authors and Affiliations

  1. School of Life Sciences, Central University of Gujarat, Gandhinagar, India

    Bhavana Jodha & Sunita Patel

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  1. Bhavana Jodha
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  2. Sunita Patel
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Correspondence to Sunita Patel .

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Editors and Affiliations

  1. School of Pharmacy, National Forensic Science University, Gandhinagar, Gujarat, India

    Deep Pooja

  2. School of Nano Sciences, Central University of Gujarat, Gandhinagar, Gujarat, India

    Hitesh Kulhari

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© 2024 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

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Jodha, B., Patel, S. (2024). Therapeutic Phytoconstituents-II. In: Pooja, D., Kulhari, H. (eds) Nanotechnology Based Delivery of Phytoconstituents and Cosmeceuticals. Springer, Singapore. https://doi.org/10.1007/978-981-99-5314-1_3

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