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Harnessing Knowledge from COVID-19 Scenario for New Generation Vaccine Development to Control Pandemics in Animals

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Biotechnological Interventions Augmenting Livestock Health and Production

Part of the book series: Livestock Diseases and Management ((LDM))

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Abstract

Vaccines are the most efficient and economic tool to control and prevent infectious diseases in animals. First-generation vaccines; live attenuated and inactivated vaccines have been successful in producing healthy and productive livestock and controlling various infectious diseases. However, with increasing rate of emerging infections and the risk of resurgence of vaccine-controlled diseases, new vaccine strategies that are safer to use, and implicit both humoral and cellular immune responses need to be devised. Older generation vaccines are not capable of controlling the urgencies caused by newer epidemics and pandemics. The next-generation vaccine platforms such as recombinant subunit, virus-like particles, DNA, RNA, viral-vectored vaccines, etc., are capable of eliciting both humoral and cellular immune response, are cost-effective, and safer to use. With the emergence of COVID-19 pandemic, the field of medical science has excelled in producing fastest vaccines ever using next-generation vaccine technologies and reverse vaccinology. Similarly, the information of new generation vaccine platforms can be exploited in devising better vaccine development strategies in the field of veterinary science for controlling any such pandemics among animals in near future. This chapter elaborates upon various old generation and new generation vaccine platform technologies, reverse vaccinology, their role in veterinary vaccinology, and how these newer vaccine platforms can be deployed to design novel, efficient, and safer vaccines to control pandemics in animals, thereby also preventing zoonotic diseases under one-health program.

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Gautam, A., Gautam, H., Sharma, A., Malik, Y.S. (2023). Harnessing Knowledge from COVID-19 Scenario for New Generation Vaccine Development to Control Pandemics in Animals. In: Mukhopadhyay, C.S., Choudhary, R.K., Panwar, H., Malik, Y.S. (eds) Biotechnological Interventions Augmenting Livestock Health and Production. Livestock Diseases and Management. Springer, Singapore. https://doi.org/10.1007/978-981-99-2209-3_14

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