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Diseases of the Nipple

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Holistic Approach to Breast Disease

Abstract

Nipple-areolar complex present in the central quadrant of the breast has unique characteristics and can present with a spectrum of diseases such as congenital, inflammatory, benign, and malignant diseases. Approach to diseases of the nipple, especially in cases where the patients present with nipple discharge should be multimodal including clinical, radiological, and pathological evaluation, for an effective management.

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References

  1. Nicholson BT, Harvey JA, Cohen MA. Nipple-areolar complex: normal anatomy and benign and malignant processes. Radiographics. 2009;29(2):509–23.

    Article  PubMed  Google Scholar 

  2. Da Costa D, Taddese A, Cure ML, Gerson D, Poppiti R, Esserman LE. Common and unusual diseases of the nipple-areolar complex. Radiographics. 2007;27(suppl_1):S65–77.

    Article  PubMed  Google Scholar 

  3. Bland KI, Klimberg VS, Copeland EM, Gradishar WJ. The breast–comprehensive management of benign and malignant diseases. Amsterdam: Elsevier; 2017. p. 38–40, 57–78.

    Google Scholar 

  4. Song HS, Jung SE, Kim YC, Lee ES. Nipple eczema, an indicative manifestation of atopic dermatitis? A clinical, histological, and immunohistochemical study. Am J Dermatopathol. 2015;37:284–8. https://doi.org/10.1097/DAD.0000000000000195.

    Article  PubMed  Google Scholar 

  5. Kim SK, Won YH, Kim S. Nipple eczema: a diagnostic challenge of allergic contact dermatitis. Ann Dermatol. 2014;26:413–4. https://doi.org/10.5021/ad.2014.26.3.413.

    Article  PubMed Central  Google Scholar 

  6. Stone K, Wheeler A. A review of anatomy, physiology, and benign pathology of the nipple. Ann Surg Oncol. 2015;22:3236–40. https://doi.org/10.1245/s10434-015-4760-4.

    Article  PubMed  Google Scholar 

  7. Harris JR, Lipman ME, Morrow M, Osborne CK. Diseases of the breast. 4th ed. Philadelphia: Lippincott; 2002. p. 42–7.

    Google Scholar 

  8. Salemis NS. Florid papillomatosis of the nipple: a rare presentation and review of the literature. Breast Dis. 2015;35(2):153–6. https://doi.org/10.3233/BD-150397.

    Article  PubMed  Google Scholar 

  9. Wang C, Wang X, Ma R. Diagnosis and surgical treatment of nipple adenoma. ANZ J Surg. 2015;85:444–7. https://doi.org/10.1111/ans.12744.

    Article  PubMed  Google Scholar 

  10. Sripathi S, Ayachit A, Kadavigere R, Kumar S, Eleti A, Sraj A. Spectrum of imaging findings in Paget's disease of the breast-a pictorial review. Insights Imaging. 2015;6(4):419–29. https://doi.org/10.1007/s13244-015-0415-z.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Ikeda DM, Helvie MA, Frank TS, Chapel KL, Anderson IT. Paget disease of the nipple: radiologic-pathologic correlation. Radiology. 1993;189(1):89–94. https://doi.org/10.1148/radiology.189.1.8396786.

    Article  CAS  Google Scholar 

  12. Babu B, Dev B, Mohanapriya T, Shalini CNS. Bilateral mammary Paget disease in a young adult female. Radiol Case Rep. 2018;13(3):586–91. https://doi.org/10.1016/j.radcr.2018.02.018.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Lim HS, Jeong SJ, Lee JS, Park MH, Kim JW, Shin SS. Paget disease of the breast: mammographic, US, and MR imaging findings with pathologic correlation. Radiographics. 2011;31(7):1973–87.

    Article  PubMed  Google Scholar 

  14. Carty NJ, Mudan SS, Ravichandran D, et al. Prospective study of outcome in women presenting with nipple discharge. Ann R Coll Surg Engl. 1994;76:387–9.

    CAS  PubMed  PubMed Central  Google Scholar 

  15. Simmons R, Adamovich T, Brennan M, et al. Non surgical evaluation of pathogical nipple discharge. Ann Surg Oncol. 2003;10:113.

    Article  PubMed  Google Scholar 

  16. Kasales CJ, Han B, Smith JS, Chetlen AL, Kaneda HJ, Shereef S. Nonpuerperal mastitis and subareolar abscess of the breast. Am J Roentgenol. 2014;202(2):W133–9.

    Article  Google Scholar 

  17. Paget J. On disease of the mammary areola preceding cancer of the mammary gland. Cancer J Clin. 1874;10:87–9.

    Google Scholar 

  18. Ashikari R, Park K, Huvos AG, Urban JA. Paget’s disease of the breast. Cancer. 1970;26(3):680–5. https://doi.org/10.1002/1097-0142(197009)26:3<680::AID-CNCR2820260329>3.0.CO;2-P.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Surgery, Sri Ramachandra Institute of Higher Education and Research, Chennai, India

    Mohana Priya

  2. Department of Radiology, Sri Ramachandra Institute of Higher Education and Research, Chennai, India

    Mehak Garg

  3. Department of Pathology, Sri Ramachandra Institute of Higher Education and Research, Chennai, India

    Bhawna Dev & Sandhya Sundaram

Authors
  1. Mohana Priya
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  2. Mehak Garg
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  3. Bhawna Dev
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  4. Sandhya Sundaram
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Corresponding author

Correspondence to Mohana Priya .

Editor information

Editors and Affiliations

  1. Department of Radiology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India

    Bhawna Dev

  2. Department of Pathology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India

    Leena Dennis Joseph

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© 2023 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

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Priya, M., Garg, M., Dev, B., Sundaram, S. (2023). Diseases of the Nipple. In: Dev, B., Joseph, L.D. (eds) Holistic Approach to Breast Disease. Springer, Singapore. https://doi.org/10.1007/978-981-99-0035-0_29

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  • DOI: https://doi.org/10.1007/978-981-99-0035-0_29

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-99-0034-3

  • Online ISBN: 978-981-99-0035-0

  • eBook Packages: MedicineMedicine (R0)

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