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Introduction to Lung Diseases

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Targeting Cellular Signalling Pathways in Lung Diseases

Abstract

Lungs come in contact with external environmental factors such as smoke, pollens, microbes, dust, environmental chemicals, and various other pollutants continuously. Exposure of lungs to these factors increases the risk of lungs to develop various diseases and disorders. In the United States, lung diseases are the third top reason of deaths. In infants, the majority of deaths are due to lung diseases and other breathing problems. Lung diseases may affect the whole respiratory system including the trachea, bronchi, bronchioles, alveoli, pleurae, pleural cavity, and nerves and muscles responsible for respiration or part of the respiratory system. Respiratory diseases make gas exchange difficult in air-breathing animals. This can lead to mild and self-limiting to life-threatening conditions. Lung diseases include asthma, chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), lung cancer, and various bacterial as well as viral infections like influenza, pneumococcal, respiratory syncytial virus, etc. These conditions if are not treated well within time can lead to serious health complications and may often produce life-threatening situations. The quality and productivity of the life of the patient are severely hampered because of respiratory diseases due to the related symptoms like breathlessness and chronic cough. This chapter introduces different kinds of respiratory disorders along with their etiology, epidemiology, pathophysiology, sign and symptoms, and treatment.

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Authors and Affiliations

  1. Divine College of Pharmacy, Nashik, Maharashtra, India

    Shivraj Popat Jadhav

  2. School of Pharmacy, Suresh Gyan Vihar University, Jaipur, India

    Himmat Singh, Ritu Gilhotra, Anurag Mishra & Gaurav Gupta

  3. Department of Pharmaceutical Medicine, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India

    Salman Hussain

  4. Department of Chemistry, University of Petroleum & Energy Studies, Dehradun, India

    Parteek Prasher

  5. Department of Chemical Pathology, School of Pathology, Faculty of Health Sciences and National Health Laboratory Service, University of the Free State, Bloemfontein, South Africa

    Anand Krishnan

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  1. Graduate School of Health, Discipline of Pharmacy, University of Technology Sydney, Sydney, NSW, Australia

    Kamal Dua

  2. Drug Development and Innovation Centre, University of Alberta, Edmonton, AB, Canada

    Raimar Löbenberg

  3. Haematology and Hemotherapy Center, State University of Campinas, Campinas, São Paulo, Brazil

    Ângela Cristina Malheiros Luzo

  4. Graduate School of Health, Discipline of Pharmacy, University of Technology Sydney, Sydney, NSW, Australia

    Shakti Shukla

  5. School of Pharmaceutical Sciences & Division of Research & Development, Lovely Professional University, Phagwara, Punjab, India

    Saurabh Satija

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Jadhav, S.P. et al. (2021). Introduction to Lung Diseases. In: Dua, K., Löbenberg, R., Malheiros Luzo, Â.C., Shukla, S., Satija, S. (eds) Targeting Cellular Signalling Pathways in Lung Diseases. Springer, Singapore. https://doi.org/10.1007/978-981-33-6827-9_1

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