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Wound Healing and Scarring

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Total Scar Management

Abstract

Skin acts as the main protective barrier from the external environment. Compromise to this barrier, following trauma, burns, or surgical resection, can result in chronic wounds and scars that physically and emotionally devastate patients worldwide. Improved understanding of the cellular and molecular mechanisms underpinning wound healing holds potential to improve the lives of such individuals, as well as drive the development of new therapeutics. In this chapter, we focus on describing the basic mechanisms underlying mammalian response to injury, highlighting the local and systemic factors affecting healing, as well as presenting recent advances in the management of chronic wounds and scars.

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Authors and Affiliations

  1. The Wound Care Center, Brigham and Women’s Hospital, Boston, MA, USA

    Adriana C. Panayi & Dennis P. Orgill

  2. Harvard Medical School, Harvard Business School, Boston, MA, USA

    Chanan Reitblat & Dennis P. Orgill

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  1. Adriana C. Panayi
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  2. Chanan Reitblat
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  3. Dennis P. Orgill
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Correspondence to Dennis P. Orgill .

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Editors and Affiliations

  1. Department of Plastic, Reconstructive and Aesthetic Surgery, Nippon Medical School, Tokyo, Japan

    Rei Ogawa

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Panayi, A.C., Reitblat, C., Orgill, D.P. (2020). Wound Healing and Scarring. In: Ogawa, R. (eds) Total Scar Management. Springer, Singapore. https://doi.org/10.1007/978-981-32-9791-3_1

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