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Research Applications of Positron Emission Tomography/Magnetic Resonance (PET/MR) Imaging in Epilepsy

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PET/MR: Functional and Molecular Imaging of Neurological Diseases and Neurosciences

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Abstract

Epilepsy is a neurological condition involving recurrent seizures that are induced by abnormal neuronal discharges in the brain. According to statistics, there are approximately 6.5 million individuals with epilepsy worldwide. The high disability and fatality rates, numerous complications, and high medical costs associated with epilepsy place a heavy burden on families and society. Over the past few decades, there has been a gradual deepening in our understanding of epilepsy, which has in turn brought about a series of transformations in the diagnosis and classification of this condition. Nevertheless, the pathogenesis of epilepsy remains poorly understood. Recent advances in neuroimaging have led to the emergence of new PET and MRI techniques, including structural MRI (sMRI), magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI), perfusion-weighted imaging (PWI), and functional MRI (fMRI). These techniques have promoted the rapid development of research on epilepsy, encompassing areas such as surgical planning, cognitive function in patients with epilepsy, and the pathophysiological mechanisms of epilepsy. The findings of this research have contributed to a deeper understanding of epilepsy, and have broadened the indications for the surgical treatment of patients with epilepsy.

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Authors and Affiliations

  1. Department of Radiology and Nuclear Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China

    Chao Zhang, Kun Shang, Jingjuan Wang & Jie Lu

  2. Center for Cognition and Brain Disorders, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China

    Yufeng Zang

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  1. Chao Zhang
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  2. Kun Shang
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  3. Jingjuan Wang
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  4. Yufeng Zang
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  5. Jie Lu
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Editors and Affiliations

  1. Department of Radiology and Nuclear Medicine, Xuanwu HospitalCapital Medical Uniersity, Beijing, China

    Jie Lu

  2. Department of Neurosurgery Xuanwu Hospital, Capital Medical University, Beijing, China

    Guoguang Zhao

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© 2023 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

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Zhang, C., Shang, K., Wang, J., Zang, Y., Lu, J. (2023). Research Applications of Positron Emission Tomography/Magnetic Resonance (PET/MR) Imaging in Epilepsy. In: Lu, J., Zhao, G. (eds) PET/MR: Functional and Molecular Imaging of Neurological Diseases and Neurosciences. Springer, Singapore. https://doi.org/10.1007/978-981-19-9902-4_10

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  • DOI: https://doi.org/10.1007/978-981-19-9902-4_10

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-19-9901-7

  • Online ISBN: 978-981-19-9902-4

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