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Combined Liver and Kidney Transplant

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Peri-operative Anesthetic Management in Liver Transplantation

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Abstract

Single organ liver and kidney transplants are well established as standards of care for selected patients with severe liver and kidney disease, respectively [1]. Severe dysfunction in multiple organ systems, either due to a single pathological process or as a consequence of single system disease, creates a challenge for transplant medicine. Studies have demonstrated relatively poorer outcomes in patients with multiple organ dysfunction undergoing single organ transplant [2, 3]. This has led to an expansion of combined solid organ transplantation over recent years [4]. Renal insufficiency is very common among ESLD patients awaiting liver transplantation (LT) and affects clinical outcomes both before, and following LT [3]. Since renal function plays significant role in the outcome of patients awaiting LT, the model for end-stage liver disease (MELD) has almost universally replaced other wait list criteria which failed to incorporate a measure of renal function [5].

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Authors and Affiliations

  1. Department of Anesthesia and Peri-Operative Medicine, London Health Sciences Centre, Western University, London, ON, Canada

    Sonja Payne, Nelson Gonzalez & Achal Dhir

Authors
  1. Sonja Payne
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  2. Nelson Gonzalez
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  3. Achal Dhir
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Corresponding author

Correspondence to Achal Dhir .

Editor information

Editors and Affiliations

  1. Liver Transplant, GI Anesthesia & Intensive Care, Medanta The Medicity, Gurgaon, India

    Vijay Vohra

  2. Liver Transplant, GI Anesthesia & Critical Care, Medanta The Medicity, Gurgaon, Haryana, India

    Nikunj Gupta

  3. Liver Transplant & General Anaesthesia, Narayana Superspeciality Hospital, Gurgaon, India

    Annu Sarin Jolly

  4. Liver Transplant, GI Anesthesia & Critical Care, Formerly at Medanta The Medicity, Gurgaon, India

    Seema Bhalotra

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© 2023 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

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Payne, S., Gonzalez, N., Dhir, A. (2023). Combined Liver and Kidney Transplant. In: Vohra, V., Gupta, N., Jolly, A.S., Bhalotra, S. (eds) Peri-operative Anesthetic Management in Liver Transplantation. Springer, Singapore. https://doi.org/10.1007/978-981-19-6045-1_44

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  • DOI: https://doi.org/10.1007/978-981-19-6045-1_44

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-19-6044-4

  • Online ISBN: 978-981-19-6045-1

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