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Organic–Inorganic Nanohybrid-Based Electrochemical Biosensors

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Hybrid Nanomaterials

Part of the book series: Materials Horizons: From Nature to Nanomaterials ((MHFNN))

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Abstract

Biosensor is an emerging class of sensors that received much attention due to their wide range of applications. These are interpretative appliances that translate a biochemical reaction into an electric signal. The biomolecule is used as a recognition and sensing element to recognize and quantify the analyte of interest in a catalytic or binding event. The interaction between the biomolecule and the analyte produces an electrical response monitored by transducer in the form of signal. The sensitivity and selectivity of biosensors are based on the biomolecule, and these properties of biosensors can be further enhanced by appropriate modifications. The immobilization of biosensing element onto the host substrate offered improved characteristics to resulted modified material and biosensors. The inorganic substrate has particular properties like high mechanical and thermal strength, while organic substrate provides high electron transfer properties and conductivities. The combination of organic and inorganic materials in the form of hybrids is emerged as an efficient material as a substrate to immobilization the biomolecules and could offer the combined characteristics of organic and inorganic materials that are not possible otherwise. The properties could be further enhanced by preparing these hybrid materials on nanoscale due to high surface and improved activity. Specifically, the name biosensor is given on the basis of bioelement present in its structure and working of transducer. Electrochemical biosensors are those which changes the biochemical reaction into electrical signal. In this chapter, we mainly discussed biosensors, classification of biosensors, organic and inorganic substrate used for biosensors, organic–inorganic nanohybrid as a substrate, organic–inorganic nanohybrids as recognition element in electrochemical biosensing, immobilization of biomolecules and applications of biosensors.

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Author information

Authors and Affiliations

  1. Department of Chemistry, COMSATS University Islamabad, Abbottabad Campus, 22060, Pakistan

    Aneeqa Batool & Tauqir A. Sherazi

  2. Department of Chemistry, Government College University, Faisalabad, 38000, Pakistan

    Syed Ali Raza Naqvi

Authors
  1. Aneeqa Batool
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  2. Tauqir A. Sherazi
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  3. Syed Ali Raza Naqvi
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Corresponding author

Correspondence to Tauqir A. Sherazi .

Editor information

Editors and Affiliations

  1. Department of Chemistry, University of Sahiwal, Sahiwal, Pakistan

    Komal Rizwan

  2. Department of Life Science and Food Engineering, Huaiyin Institute of Technology, Huaian, China

    Muhammad Bilal

  3. Department of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai, China

    Tahir Rasheed

  4. Institute of Tropical Technology, Vietnam Academy of Science and Technology, Hanoi, Vietnam

    Tuan Anh Nguyen

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Batool, A., Sherazi, T.A., Naqvi, S.A.R. (2022). Organic–Inorganic Nanohybrid-Based Electrochemical Biosensors. In: Rizwan, K., Bilal, M., Rasheed, T., Nguyen, T.A. (eds) Hybrid Nanomaterials. Materials Horizons: From Nature to Nanomaterials. Springer, Singapore. https://doi.org/10.1007/978-981-19-4538-0_8

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