Abstract
Takayasu’s arteritis is an example of large-vessel vasculitides that has a distinct propensity of involving the aorta and its major branches. The inflammation leads to stenosis or obliteration of the vascular lumens with consequent end-organ ischemia and organ-specific symptoms. Most of the patients are young women, who present frequently with cardiovascular symptoms. This case illustrates the occurrence of TA in a child with extensive stenotic aortoarteriopathy. The disease forms the third common vasculitis in the pediatric population with a slight female predominance. It also highlights severe, progressive, and/or refractory disease with repeated flares.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Further Reading
Aeschlimann FA, Barra L, Alsolaimani R, Benseler SM, Hebert D, Khalidi N, et al. Presentation and disease course of childhood-onset versus adult-onset Takayasu arteritis. Arthritis Rheumatol. 2019;71:315–23.
Bolek EC, Kaya Akca U, Sari A, Sag E, Demir S, Kilic L, et al. Takayasu’s arteritis more severe in children? Clin Exp Rheumatol. 2021;39(Suppl 129):32–8.
Clemente G, Silva CA, Sacchetti SB, Ferriani VPL, Oliveira SK, Sztajnbok F, et al. Takayasu arteritis in childhood: misdiagnoses at disease onset and associated diseases. Rheumatol Int. 2018;38:1089–94.
Di Santo M, Stelmaszewski EV, Villa A. Takayasu arteritis in paediatrics. Cardiol Young. 2018;28:354–61.
Espinoza JL, Ai S, Matsumura I. New insights on the pathogenesis of Takayasu arteritis: revisiting the microbial theory. Pathogens. 2018;7:73.
Gupta H, Kaur N, Saxena A, Jagia P, Kumar S, Gupta SK, et al. Non-specific aortoarteritis (NSAA) in children: a prospective observational study. BMJ Paediatr Open. 2021;5:e001106.
Hrisrova D, Marchev S. Takayasu arteritis: a systematic review. Acta Med Bulg. 2019;46:56–64.
Idhrees M, Thilagavathi N, Bashir M, Velayudhan BV. Management of cardiac manifestations of Takayasu arteritis. Vessel Plus. 2020;4:23.
Pugh D, Grayson P, Basu N, Dhaun N. Aortitis: recent advances, current concepts and future possibilities. Heart. 2021;107:1620–9.
Renauer P, Sawalha AH. The genetics of Takayasu arteritis. Presse Med. 2017;46:e179–87.
Russo RAG, Katsicas MM. Takayasu arteritis. Front Pediatr. 2018;6:265.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2022 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Vaideeswar, P. (2022). Childhood Takayasu’s Arteritis. In: Vaideeswar, P. (eds) Tropical Cardiovascular Pathology. Springer, Singapore. https://doi.org/10.1007/978-981-19-3720-0_63
Download citation
DOI: https://doi.org/10.1007/978-981-19-3720-0_63
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-19-3719-4
Online ISBN: 978-981-19-3720-0
eBook Packages: MedicineMedicine (R0)