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Clinical Research of Kawasaki Disease

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Kawasaki Disease

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Abstract

Kawasaki disease (KD) is an acute systemic inflammation illness. The diagnostic five clinical manifestations which notable in acute phase are bilateral nonexudative bulbar conjunctivitis which sparing the limbal area, dry fissured lips accompanied with hyperemia in oropharyngeal mucosa or strawberry tongue, unilateral anterior cervical lymphadenopathy, changes in the peripheral extremities, and polymorphous skin rash. Recognition of nonspecific clinical features observed in incomplete KD is key for prompt diagnosis. Kawasaki disease shock syndrome is a potentially life-threatening type of KD. Refractory KD patients are IVIG-resistant and at higher risk of developing coronary artery lesions (CALs). Infants under 1 year of age and adolescent with KD may have different manifestations and high risk of developing CALs.

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  1. Mackay Children’s Hospital, Taipei, Taiwan

    Hsin Chi

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  1. Kawasaki Disease Center, Department of Pediatrics and College of Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, Kaohsiung, Taiwan

    Ho-Chang Kuo

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Chi, H. (2022). Clinical Research of Kawasaki Disease. In: Kuo, HC. (eds) Kawasaki Disease. Springer, Singapore. https://doi.org/10.1007/978-981-19-2944-1_9

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