Abstract
Genital herpes is an infectious disease caused by herpes simplex virus (HSV) type 1 (HSV-1)/2 (HSV-2). HSV-1 mainly infects the face, and HSV-2 mainly infects the vulva, but genital herpes caused by HSV-1 is also common. After sexual contact, HSV-1 infects the cutaneous mucosa and proliferates at the site of infection. Then HSV-1/2 ascends the sensory nerves and causes latent infection of the ganglia. Genital herpes is clinically divided into primary infection and recurrent herpes outbreaks. Primary infection is divided into first-episode primary infection and first-episode non-primary infection. Women with first-episode primary infection are infected with genital herpes for the first time, and women with first-episode non-primary infection has antibodies but has been asymptomatic and has been reactivated due to a decrease in immune function. The recurrence rate is higher in HSV-2 [1]. The main symptoms are blisters and shallow ulcerative lesions with severe pain on the vulvar mucosa, vaginal wall, and cervix. In the first-episode primary infection, the levels of HSV in the genital tract are highest, and patients have symptoms of fever above 38 °C, dysuria, and difficulty walking.
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Inaoka, N., Iriyama, T. (2022). Herpes Infection. In: Matsuda, Y. (eds) Cerebral Palsy. Springer, Singapore. https://doi.org/10.1007/978-981-19-2217-6_9
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DOI: https://doi.org/10.1007/978-981-19-2217-6_9
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