Skip to main content

Use of Metrological Characteristics in Ultrasound Imaging and Artificial Intelligence Techniques for Disease Prediction in Soft Tissue Organs

  • Living reference work entry
  • First Online:
Handbook of Metrology and Applications
  • 23 Accesses

Abstract

The global population nowadays is severely affected by various diseases of the soft tissue organs caused mainly because of some infection, heredity, change of lifestyle, etc. The timely detection and accurate diagnosis of these health conditions are of utmost importance in order to improve the chances of recovery and survival. Many medical imaging modalities have proven to effectively diagnose these diseases and their progression in a noninvasive way. Out of all the available modalities, ultrasound is the preferred mode of examination for imaging soft tissue organs for disease prediction because of its ease of use, low cost, portability, and lack of ionizing radiation. The radiologists manually study these scans for making an accurate diagnosis of the underlying condition. However, ultrasound imaging is highly operator-dependent and its effectiveness is adversely affected because of the presence of speckle noise. Therefore, to overcome these issues and for an efficient disease diagnosis, different computer-aided diagnostic (CAD) systems have been developed by researchers using artificial intelligence techniques along with the metrological characteristics of the diseased part as visible on the ultrasound scan of the organ under study. The main purpose of the present chapter is to shed light on the different types of diseases that affect the soft tissue organs like kidney, liver, thyroid, breast and their sonographic appearances, and characteristics. The chapter further describes methodologies developed in recent existing literature (year 2017 onwards) for the classification of diseases using ultrasound images of these organs through a CAD system using state-of-the-art deep learning and machine learning methods. The chapter also gives an insight into designing an efficient CAD system for the classification of breast tumors. The authors in the chapter have used nonsubsampled contourlet transform (NSCT) for multiresolution analysis of the original tumor images. From the subimages obtained using NSCT, extraction of texture features has been carried out using gray level co-occurrence matrix (GLCM), whereas shape features have been computed from the preprocessed tumor images. The computed feature set (texture + shape) has been used for classifying breast tumors using an adaptive neuro-fuzzy classifier with linguistic hedges (ANFC-LH) classifier based on the optimal features selected on the basis of the hedge values associated with the fuzzy rules.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

References

  • Acharya UR, Fujita H, Bhat S, Raghavendra U, Gudigar A, Molinari F, Vijaynathan A, Ng KH (2016) Decision support system for fatty liver disease using GIST descriptors extracted from ultrasound images. Inf Fusion 29:32–39

    Article  Google Scholar 

  • Acharya UR, Koh JEW, Hagiwara Y, Tan JH, Gertych A, Vijaynathan A, Yaakup NA, Abdullah BJJ, Fabell MKBK, Yeong CH (2018) Automated diagnosis of focal liver lesions using bidirectional empirical mode decomposition features. Comput Biol Med 94:11–18

    Article  Google Scholar 

  • Acharya UR, Meiburger KM, Koh JEW, Hagiwara Y, Oh SL, Leong SS, Ciaccio EJ, Wong JHD, Md Shah MN, Molinari F, Ng KH (2019) Automated detection of chronic kidney disease using higher-order features and elongated quinary patterns form B-mode ultrasound images. Neural Comput Appl 32(15):11163–11172

    Article  Google Scholar 

  • Ahmad R, Mohanty BK (2021) Chronic kidney disease stage identification using texture analysis of ultrasound images. Biomed Signal Process Control 69:102695. https://doi.org/10.1016/j.bspc.2021.102695

    Article  Google Scholar 

  • Aja-Fernandez S, Alberola Lopez S (2006) On the estimation of the coefficient of variation for anisotropic diffusion speckle filtering. IEEE Trans Image Process 15(9):2694–2701

    Article  Google Scholar 

  • Alexander LF, Patel NJ, Caserta MP, Robbin ML (2020) Thyroid ultrasound: diffuse and nodular disease. Radiol Clin N Am 58(6):1041–1057

    Article  Google Scholar 

  • American kidney fund (2021) Chronic kidney disease. Available at: https://www.kidneyfund.org/kidney-disease/chronic-kidney-disease-ckd/

  • American Thyroid Association. Available at: https://www.thyroid.org/media-main/press-room/

  • Amin MN, Rushdi MA, Marzaban RN, Yosry A, Kim K, Mahmoud AM (2019) Wavelet-based computationally-efficient computer-aided characterization of liver staetosis using conventional B-mode ultrasound images. Biomed Signal Process Control 52:84–96

    Article  Google Scholar 

  • Ataide EJG, Ponugoti N, Illanes A, Schenke S, Kreissl M, Friebe M (2020) Thyroid nodule classification for physician decision support using machine learning-evaluated geometric and morphological features. Sensors 20(21):6110

    Article  Google Scholar 

  • Bharti P, Mittal D, Ananthasivan R (2018) Preliminary study of chronic liver classification on ultrasound images using an ensemble model. Ultrason Imaging 40(6):357–379

    Article  Google Scholar 

  • Brown S (2020) Liver diseases: what you should know. Available at: https://www.webmd.com/hepatitis/liver-and-hepatic-diseases

  • Cancer.net (2021) Uterine cancer: statistics. Available at: https://www.cancer.net/cancer-types/uterine-cancer/statistics

  • Centres for Disease Control and Prevention (2021) Chronic kidney disease in the United States, 2021. US Department of Health and Human Services, Centers for Disease Control and Prevention, Atlanta. Available at: https://www.cdc.gov/kidney/disease/publications -resources/ckd-national-facts.html

  • Cetisli B (2010a) Development of an adaptive neuro-fuzzy classifier using linguistic hedges: part 1. Expert Syst Appl 37:6093–6101

    Article  Google Scholar 

  • Cetisli B (2010b) Development of an adaptive neuro-fuzzy classifier using linguistic hedges: part 2. Expert Syst Appl 37:6102–6108

    Article  Google Scholar 

  • Chan TF, Vese LA (2001) Active contours without edges. IEEE Trans Image Process 10(2):266–277

    Article  MATH  Google Scholar 

  • Chaudhary V, Bano S (2013) Thyroid ultrasound. Indian J Endocrinol Metab 17(2):219–227

    Article  Google Scholar 

  • Cheemerla S, Balakrishnan M (2021) Global epidemiology of chronic liver disease. Clin Liver Dis 17(5):365–370

    Article  Google Scholar 

  • Chen CJ, Pai TW, Hsu HH, Lee CH, Chen KS, Chen YC (2019) Prediction of chronic kidney disease stages by renal ultrasound imaging. Enterp Inf Syst 14(2):178–195

    Article  Google Scholar 

  • Chi J, Walia E, Babyn P, Wang J, Groot G, Eramian M (2017) Thyroid nodule classification in ultrasound images by fine-tuning deep convolutional neural network. J Digit Imaging 30:477–486

    Article  Google Scholar 

  • Cleveland clinic (2020) Thyroid disease. Available at: https://my.clevelandclinic.org/health/diseases/8541-thyroid-disease

  • Cytcare cancer hospitals (2022) Breast cancer statistics in India. Available at: https://cytecare.com/blog/statistics-of-breast-cancer/#:~:text=One%20in%20twenty%2Deight%20Indian,group%20(1%20in%2060)

  • da Cunha AL, Zhou J, Do MN (2006) The nonsubsampled contourlet transform: theory, design, and applications. IEEE Trans Image Process 15(10):3089–3091

    Article  Google Scholar 

  • Dandan L, Huanhuan M, Xiang L, Yu J, Yi S (2019) Classification of diffuse liver diseases based on ultrasound images with multimodal features. In: Proceedings of IEEE international instrumentation and measurement technology conference. IEEE. https://doi.org/10.1109/I2MTC.2019.8827174

    Chapter  Google Scholar 

  • Davis PL, Staiger MJ, Harris KB, Ganott MA, Klementaviciene J, McCarty KS, Tobon H (1996) Breast cancer measurements with magnetic resonance imaging, ultrasonography and mammography. Breast Cancer Res Treat 37:1–9

    Article  Google Scholar 

  • Do MN, Vetterli M (2005) The contourlet transform: an efficient directional multiresolution image representation. IEEE Trans Image Process 14(12):2091–2106

    Article  Google Scholar 

  • DTE Staff (2018) 1 in 10 Indians have hypothyroidism. Available at: https://www.downtoearth.org.in/news/health/1-in-10-indians-have-hypothyroidism-61693

  • Fawcett T (2006) An introduction to ROC analysis. Pattern Recogn Lett 27(8):861–874

    Article  MathSciNet  Google Scholar 

  • Fujioka T, Kubota K, Mori M, Kikuchi Y, Katsuta L, Kasahara M, Oda G, Ishiba T, Nakagawa T, Tateishi U (2019) Distinction between benign and malignant breast masses at breast ultrasound using deep learning method with convolutional neural network. Jpn J Radiol 37(6):466–472

    Article  Google Scholar 

  • Geertsma T (2014a) Abdomen and retroperitonium. Available at: https://www.ultrasoundcases.info/cases/abdomen-and-retroperitoneum/liver

  • Geertsma T (2014b) Breast and axilla. Available at: http://ultrasoundcases.info. Accessed Dec 2016

  • Geertsma T (2014c) Head and neck. Available at: https://www.ultrasoundcases.info/cases/head-and-neck/thyroid-gland/

  • Geertsma T (2014d) Urinary tract and male reproductive system. Available at: https://www.ultrasoundcases.info/cases/urinary-tract-and-male-reproductive-system/kidn ey-and-ureter/

  • Gokhale S (2009) Ultrasound characterization of breast masses. Indian J Radiol Imaging 19(3):242–247

    Article  Google Scholar 

  • Gonzalez-Luna FA, Hernandez-Lopez J, Gomez-Flores W (2019) A performance evaluation of machine learning techniques for breast ultrasound classification. In: Proceedings of 16th international conference on electrical engineering, computing, science and automatic control. IEEE, pp 1–5

    Google Scholar 

  • Gruber IV, Rueckert M, Kagan KO, Staebler A, Siegmann KC, Hartkopf A, Wallwiener D, Hahn M (2013) Measurement of tumor size with mammography and magnetic resonance imaging as compared to histological tumor size in primary breast cancer. BMC Cancer 13:328

    Article  Google Scholar 

  • Hao PY, Xu ZY, Tian SY, Wu FL, Chen W, Wu J, Luo XN (2019) Texture branch network for chronic kidney disease screening based on ultrasound images. Front Inf Technol Electron Eng 21:1161–1170

    Article  Google Scholar 

  • Hassan TM, Elmogy M, Sallam EL (2017) Diagnosis of focal liver diseases based on deep learning technique for ultrasound images. Arab J Sci Eng 42:3127–3140

    Article  Google Scholar 

  • Johnson S (2018) Kidney health and kidney disease basics. Available at: https://www.healthline.com/health/kidney-disease

  • Kar S, Das S, Ghosh PK (2015) Applications of neuro fuzzy systems: a brief review and future outline. Appl Soft Comput 15:243–259

    Article  Google Scholar 

  • Kher R, Pawar T, Thakar V, Shah H (2015) Physical activities recognition from ambulatory ECG signals using neuro-fuzzy classifiers and support vector machines. J Med Eng Technol 39(2):138–152

    Article  Google Scholar 

  • Kim DH, Ye SY (2021) Classification of chronic kidney disease in sonography using the GLCM and artificial neural network. Diagnostics 11(5):864

    Article  Google Scholar 

  • Kim K, Song MK, Kim EK, Yoon JH (2017) Clinical application of S-detect to breast masses on ultrasonography: a study evaluating the diagnostic performance and agreement with a dedicated breast radiologist. Ultrasonography 36(1):4–9

    Article  Google Scholar 

  • Krishnamurthy RK, Radhakrishnan S, Kattuva MAK (2020) Particle swarm optimization-based liver disorder ultrasound image classification using multi-level and multi-domain features. Int J Imaging Syst Technol 31(3):1366–1385

    Article  Google Scholar 

  • Kriti VJ, Virmani J, Agarwal R (2019) Effect of despeckle filtering on classification of breast tumors using ultrasound images. Biocybern Biomed Eng 39(2):536–560

    Article  Google Scholar 

  • Kriti VJ, Virmani J, Agarwal R (2020) Deep feature extraction and classification of breast ultrasound images. Multimed Tools Appl 79:27257–27292

    Article  Google Scholar 

  • Liu T, Guo Q, Lian C, Ren X, Liang S, Yu J, Niu L, Sun W, Shen D (2019) Automated detection and classification of thyroid nodules in ultrasound images using clinical-knowledge-guided convolutional neural networks. Med Image Anal 58:101555

    Article  Google Scholar 

  • Ma J, Wu F, Zhu J, Xu D, Kong D (2017) A pre-trained convolutional neural network based method for thyroid nodule diagnosis. Ultrasonics 73:221–230

    Article  Google Scholar 

  • Mangayarkarasi T, Jamal DN (2017) PNN-based analysis system to classify renal pathologies in kidney ultrasound images. In: Proceedings of 2017 2nd international conference on computing and communications technologies (ICCCT). IEEE, pp 123–126

    Google Scholar 

  • Medline plus [Internet]. Bethesda (MD): National Library of Medicine (US) Breast diseases [Updated 2022 Jan; Cited March 2022]. Available at: https://medlineplus.gov/breastdiseases.html

  • Mishra AK, Roy P, Bandyopadhyay S, Das SK (2021) Breast ultrasound tumor classification: a machine learning-radiomics based approach. Expert Syst 38. https://doi.org/10.1111/exsy.12713

  • Moon WK, Chen IL, Yi A, Bae MS, Shin SU, Chang RF (2018) Computer-aided prediction model for axillary lymph node metastasis in breast cancer using tumor morphological and textural features on ultrasound. Comput Methods Prog Biomed 162:129–137

    Article  Google Scholar 

  • Moussa O, Khachnaoui H, Guetari R, Khlifa N (2018) Thyroid nodule classification and diagnosis in ultrasound images using fine-tuning deep convolutional neural network. Int J Imaging Syst Technol 30(1):185–195

    Article  Google Scholar 

  • National Cancer Institute (2019) Breast cancer: breast changes and conditions. Available at: https://www.cancer.gov/types/breast/breast-changes

  • Nemat H, Fehri H, Ahmadinejad N, Frangi AF, Gooya A (2018) Classification of breast lesions in ultrasonography using sparse logistic regression and morphology-based texture features. Med Phys 45(9):4112–4124

    Article  Google Scholar 

  • Nguyen DT, Kang JK, Pham TD, Batchuluum G, Park KR (2020) Ultrasound image-based diagnosis of malignant thyroid nodule using artificial intelligence. Sensors 20:1822

    Article  Google Scholar 

  • Nithya A, Appathurai A, Venkatadri N, Ramji DR, Anna Palagan C (2019) Kidney disease detection and segmentation using artificial neural network and multi-kernel k-means clustering for ultrasound images. Measurement 149:106952

    Article  Google Scholar 

  • Pasyar P, Mahmoudi T, Kouzehkanan SZM, Ahmadian A, Arabalibeik H, Soltanian N, Radmard AR (2021) Hybrid classification of diffuse liver diseases in ultrasound images using deep convolutional neural networks. Inform Med Unlocked 22:100496

    Article  Google Scholar 

  • Patel DB, Matcuk GR Jr (2018) Imaging of soft tissue sarcomas. Chin Clin Oncol 7(4):34

    Article  Google Scholar 

  • Pedraza L, Vargas C, Narvaez F, Duran O, Munoz E, Romero E (2015) An open access thyroid ultrasound image database. In: Proceedings of 10th international symposium on medical information processing and analysis, vol 9287. https://doi.org/10.1117/12.2073532

    Chapter  Google Scholar 

  • Priyanka, Kumar D (2020) Feature extraction and selection of kidney ultrasound images using GLCM and PCA. In: Proceedings of international conference on computational intelligence and data science (ICCIDS 2019). Elsevier, pp 1722–1731

    Google Scholar 

  • Raghavendra U, Gudigar A, Maithri M, Gertych A, Meiburger KM, Yeong CH, Madla C, Kongmebhol P, Molinari F, Ng KH, Acharya UR (2018) Optimized multi-level elongated quinary patterns for the assessment of thyroid nodules in ultrasound images. Comput Biol Med 95:55–62

    Article  Google Scholar 

  • Raju P, Rao VM, Rao BP (2018) Grey Wolf optimization based artificial neural network for classification of kidney images. J Circuits Syst Comput 27(14):1850231

    Article  Google Scholar 

  • Rawat J, Singh A, Bhadauria HS, Virmani J, Devgun JS (2018) Leukocyte classification using adaptive neuro-fuzzy inference system in microscopic blood images. Arab J Sci Eng 43(12):7041–7058

    Article  Google Scholar 

  • Reddy DS, Bharath R, Rajalakshmi P (2018a) A novel computer-aided diagnosis framework using deep learning for classification of fatty liver disease in ultrasound imaging. In: Proceedings of 20th international conference on e-health networking, applications and services (Healthcom). IEEE. https://doi.org/10.1109/HealthCom.2018.8531118

    Chapter  Google Scholar 

  • Reddy DS, Bharath R, Rajalakshmi P (2018b) Classification of non-alcoholic fatty liver texture using convolution neural networks. In: Proceedings of 20th international conference on e-health networking, applications and services (Healthcom). IEEE. https://doi.org/10.1109/HealthCom.2018.8531193

    Chapter  Google Scholar 

  • Rodriguez-Cristerna A, Guerrero-Cedillo CP, Donati-Olvera GA, Gomez-Flores W, Pereira WCA (2017) Study of the impact of image processing approaches on segmentation and classification of breast lesions on ultrasound. In: Proceedings of 14th international conference on electrical engineering, computer science and automatic control. IEEE, pp 299–317

    Google Scholar 

  • Sharma V, Juglan KC (2018) Automated classification of fatty and normal liver ultrasound images based on mutual information feature selection. IRBM 39(5):313–323

    Article  Google Scholar 

  • Shia WC, Lin LS, Chen DR (2021) Classification of malignant tumors in breast ultrasound using unsupervised machine learning approaches. Sci Rep 11:1418

    Article  Google Scholar 

  • Singh BK, Verma K, Thoke AS, Suri JS (2017) Risk stratification of 2D ultrasound based breast lesions using hybrid feature selection in machine learning paradigm. Measurement 105:146–157

    Article  Google Scholar 

  • Song R, Zhang L, Zhu C, Liu J, Yang J, Zhang T (2020) Thyroid nodule ultrasound image classification through hybrid feature cropping network. IEEE Access 8:64064–64074

    Article  Google Scholar 

  • Sudharson S, Kokil P (2019) Abnormality detection in renal ultrasound images using ensemble MSVM model. In: Proceedings of 2019 international conference on wireless communications signal processing and networking (WiSPNET). IEEE, pp 378–382

    Chapter  Google Scholar 

  • Sudharson S, Kokil P (2020) An ensemble of deep neural networks for kidney ultrasound image classification. Comput Methods Prog Biomed 197:105709. https://doi.org/10.1016/j.cmpb.2020.105709

    Article  Google Scholar 

  • TNN (2017) Is liver disease the next major lifestyle disease of Indian after diabetes and BP. Available at: https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/is-liver-disease-the-next-major-lifestyle-disease-of-india-after-diabetes-and bp/articleshow/58122706.cms

  • Uzunhisarcikli E, Goreke V (2018) A novel classifier model for mass classification using BI-RADS category in ultrasound images based on Type-2 fuzzy inference system. Sadhana 43(9):138

    Article  MathSciNet  MATH  Google Scholar 

  • Virmani J, Kumar V, Kalra N, Khandelwal (2013) SVM-based characterization of liver ultrasound images using wavelet packet texture descriptors. J Digit Imaging 26(3):530–543

    Article  Google Scholar 

  • Virmani J, Kumar V, Kalra N, Khandelwal N (2014) Neural network ensemble based CAD system for focal liver lesions from B-mode ultrasound. J Digit Imaging 27(4):520–537

    Article  Google Scholar 

  • Wallace R (2018) 6 common thyroid disorders & problems. Available at: https://www.healthline.com/health/common-thyroid-disorders

  • Wang H, Yang Y, Peng B, Chen Q (2017) A thyroid nodule classification method based on TI-RADS. In: Proceedings of 9th international conference on digital image processing (ICDIP 2017). International Society for Optics and Photonics, p 1042041

    Google Scholar 

  • World Health Organization (2021) Breast cancer. Available at: https://www.who.int/news-room/fact-sheets/detail/breast-cancer

  • World kidney day (2019). Available at: https://www.indiatoday.in/education-today/gk-current-affairs/story/world-kidney-day-hypertension-and-diabetes-two-major-causes-of-kidney-diseases-1477841-2019-03-14

  • Xu SDD, Chang CC, Su CT, Phu PQ (2019) Classification of liver diseases based on ultrasound image texture features. Appl Sci 9(2):342

    Article  Google Scholar 

  • Zhang HD, Heffernan PB (2012) Communicative CAD system for assisting breast imaging diagnosis. US patent application, 13/368,063

    Google Scholar 

  • Zhu Y, Fu Z, Fei J (2017) An image augmentation method using convolutional network for thyroid nodule classification by transfer learning. In: Proceedings of 3rd IEEE international conference on computer and communications. IEEE, pp 1819–1823

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ravinder Agarwal .

Editor information

Editors and Affiliations

Section Editor information

Rights and permissions

Reprints and permissions

Copyright information

© 2023 Springer Nature Singapore Pte Ltd.

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Kriti, Agarwal, R. (2023). Use of Metrological Characteristics in Ultrasound Imaging and Artificial Intelligence Techniques for Disease Prediction in Soft Tissue Organs. In: Aswal, D.K., Yadav, S., Takatsuji, T., Rachakonda, P., Kumar, H. (eds) Handbook of Metrology and Applications. Springer, Singapore. https://doi.org/10.1007/978-981-19-1550-5_132-1

Download citation

  • DOI: https://doi.org/10.1007/978-981-19-1550-5_132-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-19-1550-5

  • Online ISBN: 978-981-19-1550-5

  • eBook Packages: Springer Reference EngineeringReference Module Computer Science and Engineering

Publish with us

Policies and ethics