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Copper(II)-Catalyzed Ring Opening Polymerization of Cyclic Esters

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Polymeric Biomaterials and Bioengineering

Part of the book series: Lecture Notes in Bioengineering ((LNBE))

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Abstract

Cu(II)-catalyzed synthesis of low-molecular weight linear and hyperbranched polyesters at ambient temperature. Biodegradable polyesters are biohybrid materials, which have been widely used in various fields such as tissue engineering and regenerative medicines. Particularly, the low-molecular weight biodegradable polymers have received attention in medical applications as materials for molecular engineering. Controlled/living ring opening polymerization (ROP) of cyclic esters is the most efficient method for the synthesis of polyesters of desired molecular weight. Herein, we describe copper perchlorate hexahydrate (Cu(ClO4)2·6H2O)-catalyzed synthesis of poly(ϵ-caprolactone) (PCL) and poly(δ-valerolactone) (PVL) under solvent-free conditions at room temperature, in the presence of benzyl alcohol, 1,5-pentandiol and propargyl alcohol as external initiators. In addition, star-shaped PCL and PVL have also been synthesized using pentaerythritol and dipentaerythritol initiators. The polyesters were characterized by 1H NMR spectroscopy, gel permeation chromatography (GPC) and thermal analysis. Low-molecular weight polymers were obtained. The polymerization proceeds via an activated monomer mechanism.

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Authors and Affiliations

  1. Department of Chemistry, Sant Longowal Institute of Engineering and Technology, Longowal, Sangrur, Punjab, 148106, India

    Isha Jain & Payal Malik

Authors
  1. Isha Jain
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  2. Payal Malik
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Corresponding author

Correspondence to Payal Malik .

Editor information

Editors and Affiliations

  1. Bioengineering Laboratory, Department of Textile Technology, Indian Institute of Technology, New Delhi, Delhi, India

    Bhuvanesh Gupta

  2. Laboratory of Biocomposite Technology, Institute of Tropical Forestry and Forest Products (INTROP), Universiti Putra Malaysia, Serdang, Selangor, Malaysia

    Mohammad Jawaid

  3. Department of Chemistry, Dr. B. R. Ambedkar National Institute of Technology, Jalandhar, Punjab, India

    B. S. Kaith

  4. Amity Institute of Applied Sciences, Amity University, Noida, Uttar Pradesh, India

    Sunita Rattan

  5. Department of Chemistry, Army Cadet College Wing of Indian Military Academy, Dehradun, Uttarakhand, India

    Susheel Kalia

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Jain, I., Malik, P. (2022). Copper(II)-Catalyzed Ring Opening Polymerization of Cyclic Esters. In: Gupta, B., Jawaid, M., Kaith, B.S., Rattan, S., Kalia, S. (eds) Polymeric Biomaterials and Bioengineering. Lecture Notes in Bioengineering. Springer, Singapore. https://doi.org/10.1007/978-981-19-1084-5_8

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