Abstract
Crystalloid solutions are commonly used for fluid administration during many situations to maintain an euvolaemic state. But we, the anaesthesiologists, face many situations where we need to achieve an euvolaemic state with small amount of fluid, which cannot be achieved with crystalloids due to their lower volume effect and shorter intravascular persistence. In these situations, colloids are more useful than crystalloids. But, at the same time, colloids have other complications like problems in coagulation system, anaphylactic/anaphylactoid reactions, etc. To achieve an optimal euvolemic state, we need to use crystalloids and colloids in a planned manner individualised to the patient in a scientific approach. This chapter deals with the pharmacology of colloids useful for the anaesthesiologist and intensivist in guiding the transfusion of colloids.
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References
McCahon R, Hardman J. Pharmacology of plasma expanders. Anaesth Intensive Care Med. 2017;18:418–20.
McCahon R, Hardman J. Pharmacology of plasma expanders. Anaesth Intensive Care Med. 2014;15:436–8.
Boldt J. Intraoperative fluid therapy–crystalloid/colloid debate. Rev Mex Anest. 2005;28(1):23–8.
Mitra S, Khandelwal P. Are all colloids same? How to select the right colloid? Indian J Anaesth. 2009;53:592–607.
Boldt J. Choice of a synthetic colloid for surgery. Transfus Altern Transfus Med. 1999;1:18–25.
Westphal M, James MFM, Kozek-Langenecker S, Stocker R, Guidet B, Van Aken H. Hydroxyethyl starches: different products--different effects. Anesthesiology. 2009;111:187–202.
Dubois M, Vincent J. Colloid fluids. In: Hahn RG, Prough DS, Svensen CH, editors. Perioperative fluid therapy, vol. 1; 2016. p. 153–62.
Boldt J, Schollhorn T, Munchbach J, Pabsdorf M. A total balanced volume replacement strategy using a new balanced hydroxyethyl starch preparation (6% HES 130/0.42) in patients undergoing major abdominal surgery. Eur J Anaesthesiol. 2007;24:267–75.
Stephens R, Mythen M. Optimizing intraoperative fluid therapy. Curr Opin Anaesthesiol. 2003;16:385–92.
Caironi P, Gattinoni L. The clinical use of albumin: the point of view of a specialist in intensive care. Blood Transfus. 2009;7:259–67.
Quinlan GJ, Martin GS, Evans TW. Albumin: biochemical properties and therapeutic potential. Hepatology. 2005;41:1211–9.
Wiedermann CJ. Colloidal and pharmacological activity of albumin in clinical fluid management: recent developments. Curr Drug Therapy. 2006;1:319–28.
Peters FBT Jr. All about Albumin. Biochemistry, genetics, and medical applications. Academic Press, Inc., San Diego, California, 1996. Food Nahrung. John Wiley & Sons, Ltd. 1997;41:382.
Schnitzer JE, Oh P. Albondin-mediated capillary permeability to albumin. Differential role of receptors in endothelial transcytosis and endocytosis of native and modified albumins. J Biol Chem. 1994;269:6072–82.
Barrett KE, Barman SM, Boitano S, Reckelhoff JF. Blood as a circulatory fluid & the dynamics of blood & lymph flow. Ganong’s Medical Physiology Examination & Board review. McGraw-Hill Education: New York, NY; 2017.
Evans TW. Review article: albumin as a drug-biological effects of albumin unrelated to oncotic pressure. Aliment Pharmacol Ther. 2002;16(5):6–11.
Kragh-Hansen U, Chuang VTG, Otagiri M. Practical aspects of the ligand-binding and enzymatic properties of human serum albumin. Biol Pharm Bull. 2002;25:695–704.
Lang JD, Figueroa M, Chumley P, Aslan M, Hurt J, Tarpey MM, Alvarez B, Radi R, Freeman BA. Albumin and hydroxyethyl starch modulate oxidative inflammatory injury to vascular endothelium. Anesthesiology. 2004;100:51–8.
Marelli D, Paul A, Samson R, Edgell D, Angood P, Chiu RC. Does the addition of albumin to the prime solution in cardiopulmonary bypass affect clinical outcome? A prospective randomized study. J Thorac Cardiovasc Surg. 1989;98:751–6.
Bernardi M, Caraceni P, Navickis RJ, Wilkes MM. Albumin infusion in patients undergoing large-volume paracentesis: a meta-analysis of randomized trials. Hepatology. 2012;55:1172–81.
Moore KP, Wong F, Gines P, Bernardi M, Ochs A, Salerno F, Angeli P, Porayko M, Moreau R, Garcia-Tsao G, Jimenez W, Planas R, Arroyo V. The management of ascites in cirrhosis: report on the consensus conference of the International Ascites Club. Hepatology. 2003;38:258–66.
Shmorgun D, Claman P. The diagnosis and management of ovarian hyperstimulation syndrome. J Obstet Gynaecol Can. 2011;33:1156–62.
Tullis JL. Albumin. 2. Guidelines for clinical use. JAMA. 1977;237:460–3.
Vincent J-L, Dubois M-J, Navickis RJ, Wilkes MM. Hypoalbuminemia in acute illness: is there a rationale for intervention? A meta-analysis of cohort studies and controlled trials. Ann Surg. 2003;237:319–34.
Khan A, Milbrandt EB, Venkataraman R. Albumin and furosemide for acute lung injury. Crit Care. 2007;11:314.
Wong F, Bernardi M, Balk R, Christman B, Moreau R, Garcia-Tsao G, Patch D, Soriano G, Hoefs J, Navasa M. Sepsis in cirrhosis: report on the 7th meeting of the International Ascites Club. Gut. 2005;54:718–25.
Munoz AC, Jain NK, Gupta M. Albumin colloid. StatPearls; 2020.
Auth MKH, Kim HS, Beste M, Bonzel KE, Baumann U, Ballauff A, Wallot M, Borchers T, Vester U, Grasemann C, Hauffa B, Hoyer P, Gerken G, Voit T. Removal of metabolites, cytokines and hepatic growth factors by extracorporeal liver support in children. J Pediatr Gastroenterol Nutr. 2005;40:54–9.
Sen S, Mookerjee RP, Cheshire LM, Davies NA, Williams R, Jalan R. Albumin dialysis reduces portal pressure acutely in patients with severe alcoholic hepatitis. J Hepatol. 2005;43:142–8.
Boldt J, Suttner S. Plasma substitutes. Minerva Anestesiol. 2005;71:741–58.
Niemi TT, Miyashita R, Yamakage M. Colloid solutions: a clinical update. J Anesth. 2010;24:913–25.
Nolan J. Fluid replacement. Br Med Bull. 1999;55:821–43.
Sigurjonsson J, Hedman D, Bansch P, Schott U. Comparison of dextran and albumin on blood coagulation in patients undergoing major gynaecological surgery. Perioperative Med. 2018;7:21.
Jungheinrich C. The starch family: are they all equal? Pharmacokinetics and pharmacodynamics of hydroxyethyl starches. Transfus Altern Transfus Med. 2007;9:152–63.
Yacobi A, Stoll RG, Sum CY, Lai CM, Gupta SD, Hulse JD. Pharmacokinetics of hydroxyethyl starch in normal subjects. J Clin Pharmacol. 1982;22:206–12.
Bellmann R, Feistritzer C, Wiedermann CJ. Effect of molecular weight and substitution on tissue uptake of hydroxyethyl starch: a meta-analysis of clinical studies. Clin Pharmacokinet. 2012;51:225–36.
Bork K. Pruritus precipitated by hydroxyethyl starch: a review. Br J Dermatol. 2005;152:3–12.
Cui Y, Sun B, Wang C, Liu S, Li P, Shi J, Li E. Effects of different types of hydroxyethyl starch (HES) on microcirculation perfusion and tissue oxygenation in patients undergoing liver surgery. Int J Clin Exp Med. 2014;7:631–9.
Sommermeyer K, Cech F, Schossow R. Differences in chemical structures between waxy maize- and potato starch-based hydroxyethyl starch volume therapeutics. Transfus Altern Transfus Med. 2007;9(3):127–33.
Bulger EM, Cuschieri J, Warner K, Maier RV. Hypertonic resuscitation modulates the inflammatory response in patients with traumatic hemorrhagic shock. Ann Surg. 2007;245:635–41.
Rassam SS, Counsell DJ. Perioperative fluid therapy. Continuing Educ Anaesth Critic Care Pain. 2005;5:161–5.
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Satya Prakash, M.V.S., Govindaraj, K. (2022). Colloids. In: Prabhakar, H., S Tandon, M., Kapoor, I., Mahajan, C. (eds) Transfusion Practice in Clinical Neurosciences. Springer, Singapore. https://doi.org/10.1007/978-981-19-0954-2_4
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