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An Insight into the Synthesis and Pharmacological Activities of Indoles, Isoindoles and Carbazoles

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N-Heterocycles

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Abstract

Heterocyclic has become an imperative and largest family of organic compounds. Many heterocyclic organic moieties have possessed an extensive variety of biological activity and play a vital role in human life. Indoles, isoindoles and carbazoles, a class of fused N-heterocyclic compounds, are important biological active agents, and continue to draw appreciable attention because of their different biological properties such as anticancer, antifungal, antibacterial, antiulcer, anticonvulsant, anti-inflammatory, antidiabetic, antimalarial, antitumor, anti-HIV, antitubercular, antihypertensive, antihistamine, antihypertensive and analgesic potencies etc. In this chapter we discuss numerous biological activity and synthetic methods of indoles, isoindoles, and carbazole derivatives. Therefore, the research on the synthesis and modification of indoles, isoindoles, and carbazoles are particularly significant for researchers and pharmacologists.

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Authors and Affiliations

  1. Centre of Advanced Studies, Department of Chemistry, University of Rajasthan, Jaipur, 302004, India

    Surendra Saini, Krishan Kumar, Savita Meena, Anshu Dandia & Vijay Parewa

  2. Department of Chemistry, School of Liberal Arts and Sciences, Mody University of Science and Technology, Lakshmangarh, Rajasthan, 332311, India

    K. L. Ameta

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  1. Surendra Saini
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  2. Krishan Kumar
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  3. Savita Meena
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  4. Anshu Dandia
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  5. K. L. Ameta
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Editors and Affiliations

  1. Department of Chemistry, Mody University of Science and Technology, Lakshmangarh, India

    Keshav Lalit Ameta

  2. Chemistry, Shri Ramswaroop Memorial University, Lucknow, Uttar Pradesh, India

    Ravi Kant

  3. Chemistry, University of Insubria, Varese, Italy

    Andrea Penoni

  4. Science and High Technology, University of Insubria, Varese, Italy

    Angelo Maspero

  5. Science and High Technology, University of Insubria, Varese, Italy

    Luca Scapinello

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Saini, S., Kumar, K., Meena, S., Dandia, A., Ameta, K.L., Parewa, V. (2022). An Insight into the Synthesis and Pharmacological Activities of Indoles, Isoindoles and Carbazoles. In: Ameta, K.L., Kant, R., Penoni, A., Maspero, A., Scapinello, L. (eds) N-Heterocycles. Springer, Singapore. https://doi.org/10.1007/978-981-19-0832-3_11

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