Abstract
Management of the orbital disease in rhino-orbito-cerebral mucormycosis (ROCM) remains a dilemma. With the endoscopic method, restricted debridement of the affected area is more feasible. Managing orbital disease in a large series of ROCM cases provided some useful information.
Because any orbital surgery has its potential implications, clinicians are hesitant to proceed with the procedure. The necessity, timing, manner, and extent of orbital debridement in ROCM are controversial. This chapter covers various aspects of orbital intervention such as orbital disease mapping on MRI, indications for orbital debridement and orbital exenteration and the requirement of orbital exenteration in cerebral mucormycosis, among others. It may aid surgeons in developing a case based strategy for orbital disease management in ROCM.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Talmi YP, Goldschmied-Reouven A, Bakon M, Barshack I, Wolf M, Horowitz Z, Berkowicz M, Keller N, Kronenberg J. Rhino-orbital and rhino-orbito-cerebral mucormycosis. Otolaryngol Head Neck Surg. 2002;127(1):22–31. https://doi.org/10.1067/mhn.2002.126587.
Rangel Guerra RA, Martinez HR, Saenz C, et al. Rhinocerebral and systemic mucormycosis: clinical experience with 36 cases. J Neurol Sci. 1996;143:19–30.
Blitzer A, Lawson W, Meyers BR, et al. Patient survival factors in paranasal sinus mucormycosis. Laryngoscope. 1980;90:635–48.
Rangel Guerra R, Martinez HR, Saenz C. Mucormycosis. Report of 11 cases. Arch Neurol. 1985;42:578–81.
Bullock JD, Jampol LM, Fezza AJ. Two cases of orbital phycomycosis with recovery. Am J Ophthalmol. 1974;78:811–5.
Anand A, Anand N. Rhinocerebral mucormycosis: cure without surgery? Arch Intern Med. 1996;156:2262–9.
Peterson KL, Wang M, Canalis RF, et al. Rhinocerebral mucormycosis: evolution of the disease and treatment options. Laryngoscope. 1997;107:855–62.
Yohai RA, Bullock JD, Aziz AA, et al. Survival factors in rhino-orbital-cerebral mucormycosis. Surv Ophthalmol. 1994;39:3–22.
Schwartz JN, Donnelly EH, Klintworth GK. Ocular and orbital phycomycosis. Surv Ophthalmol. 1977;22:3–28.
Pillsbury HC, Fischer ND. Rhinocerebral mucormycosis. Arch Otolaryngol. 1977;103:600–4.
Chikley A, Ben-Ami R, Kontoyiannis DP. Mucormycosis of the central nervous system. J Fungi. 2019;5(3):59. https://doi.org/10.3390/jof5030059.
Engin Ӧ, Adriaensen GFJPM, Hoefnagels FWA, et al. A systematic review of the surgical anatomy of the orbital apex. Surg Radiol Anat. 2021;43:169–78. https://doi.org/10.1007/s00276-020-02573-w.
Goyal P, Lee S, Gupta N, Kumar Y, Mangla M, Hooda K, Li S, Mangla R. Orbital apex disorders: imaging findings and management. Neuroradiol J. 2018;31(2):104–25. https://doi.org/10.1177/1971400917740361.
Badakere A, Patil-Chhablani P. Orbital apex syndrome: a review. Eye Brain. 2019;11:63–72. https://doi.org/10.2147/EB.S180190.
Hosseini SMS, Borghei P. Rhinocerebral mucormycosis: pathways of spread. Eur Arch Otorhinolaryngol. 2005;262:932–8. https://doi.org/10.1007/s00405-005-0919-0.
Galetta SL, Wulc AE, Goldberg HI, Nichols CW, Glaser JS. Rhinocerebral mucormycosis: management and survival after carotid occlusion. Ann Neurol. 1990;28:103–7.
Vessely MB, Zitsch RP 3rd, Estrem SA, Renner G. Atypical presentations of mucormycosis in the head and neck. Otolaryngol Head Neck Surg. 1996;115:573–7.
Apinhasmit W, Chompoopong S, Methathrathip D, Sansuk R, Phetphunphiphat W. Supraorbital notch/foramen, infraorbital foramen and mental foramen in Thais: anthropometric measurements and surgical relevance. J Med Assoc Thail. 2006;89(5):675–82.
Becker M, Masterson K, Delavelle J, Viallon M, Vargas MI, Becker CD. Imaging of the optic nerve. Eur J Radiol. 2010;74(2):299–313.
Belotti F, Ferrari M, Doglietto F, et al. Ophthalmic artery originating from the anterior cerebral artery: anatomo-radiological study, histological analysis, and literature review. Neurosurg Rev. 2016;39(3):483–93.
Fisher EW, Toma A, Fisher PH, Cheeseman AD. Rhinocerebral mucormycosis: use of liposomal amphotericin B. J Laryngol Otol. 1991;105:575–7.
Hargrove RN, Wesley RE, Klippenstein KA, et al. Indications for orbital exenteration in mucormycosis. Ophthal Plast Reconstr Surg. 2006;22:286–91.
Bergstrom L, Hemenway WG, Barnhart RA. Rhinocerebral and otologic mucormycosis. Ann Otol Rhinol Laryngol. 1970;79:70–81.
Greenberg MR, Lippman SM, Grinnell VS, et al. Computed tomographic findings in orbital mucor. Western J Med. 1985;143:102–3.
Blazquez R, Pinedo A, Cosin J, et al. Nonsurgical cure of isolated cerebral mucormycosis in an intravenous drug user. Eur J Clin Microbiol Infect Dis. 1996;15:598–9.
Kohn R, Hepler R. Management of limited rhino-orbital mucormycosis without exenteration. Ophthalmology. 1985;92:1440–4.
Sponsler TA, Sassani JW, Johnson LN, et al. Ocular invasion in mucormycosis. Surv Ophthalmol. 1992;36:345–50.
Ferry AP, Abedi S. Diagnosis and management of rhinoorbitocerebral mucormycosis (phycomycosis): a report of 16 personally observed cases. Ophthalmology. 1983;90:096–104.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2022 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Gupta, N., Jain, S., Singla, P. (2022). Debates in Rhino-Orbito-Cerebral Mucormycosis: Orbital Disease Management Dilemma. In: Gupta, N., Honavar, S.G. (eds) Rhino-Orbito-Cerebral Mucormycosis. Springer, Singapore. https://doi.org/10.1007/978-981-16-9729-6_21
Download citation
DOI: https://doi.org/10.1007/978-981-16-9729-6_21
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-16-9728-9
Online ISBN: 978-981-16-9729-6
eBook Packages: MedicineMedicine (R0)