Skip to main content

EUS-Guided Liver Biopsy in Nonalcoholic Fatty Liver Disease

  • Chapter
  • First Online:
Atlas of Interventional EUS

Abstract

Liver biopsy is the gold standard in the evaluation of hepatic disease. It is extremely effective in assessing the histologic degree of fibrosis. Traditional sampling methods can be quite invasive and pose serious risks to the patient. Transjugular, percutaneous and other biopsy methods carry the risk of bleeding, pain and damage to the surrounding organs [1, 2]. The emergence of EUS-guided liver biopsy (EUS-LB) allows the endoscopist to offer a sampling method with decreased risk of adverse events and robust advantages such as decreased pain, increased safety from continuous ultrasound guidance, easily acquisition of multiple samples with a widened view of the organ in one session, and performance in the outpatient setting [2, 3]. EUS-LB accurately evaluates fibrosis in patients with fatty liver disease [4]. Several studies showcase diagnostic yields ranging from 91–100% [5–7].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Shiha GIA, Helmy A. Asian-Pacific Association for the Study of the liver (APASL) consensus guidelines on invasive and non-invasive assessment of hepatic fibrosis: a 2016 update. Hepatol Int. 2017;11:1–30.

    Article  Google Scholar 

  2. Johnson KD, Laoveeravat P, Yee EU, Perisetti A, Thandassery RB, Tharian B. Endoscopic ultrasound guided liver biopsy: recent evidence. World Journal of Gastrointestinal Endoscopy. 2020;12(3):83–97.

    Article  Google Scholar 

  3. Diehl DL. Endoscopic ultrasound-guided liver biopsy. Interventional Endoscopic Ultrasound. June 2018:83–94.

    Google Scholar 

  4. Saab SPJ, Jimenez MA, et al. Endoscopic ultrasound liver biopsies accurately predict the presence of fibrosis in patients with fatty liver. Clin Gastroenterol Hepatol. 2017;15:1477–8.

    Article  Google Scholar 

  5. Shah N, Baron T. Taking a poke at the liver: which way is best? Endoscopy International Open. 2019;07(01)

    Google Scholar 

  6. Campos S, Poley J-W, Driel LV, Bruno MJ. The role of EUS in diagnosis and treatment of liver disorders. Endoscopy International Open. 2019;07(10)

    Google Scholar 

  7. Saraireh HA, Bilal M, Singh S. Role of endoscopic ultrasound in liver disease: where do we stand in 2017? World J Hepatol. 2017;9(24):1013.

    Article  Google Scholar 

Download references

Conflicts of Interest

Ameya Deshmukh: None. Ahmed Mohammed Elmeligui: None. Javier Tejedor-Tejada: None. Jose Nieto: Consultant for Boston Scientific.

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

1 Electronic Supplementary Material

EUS-guided liver biopsy for NAFLD (MP4 18,176 kb)

Funding Support

Non-declared.

Rights and permissions

Reprints and permissions

Copyright information

© 2022 Springer Nature Singapore Pte Ltd.

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Deshmukh, A., Elmeligui, A.M., Tejedor-Tejada, J., Nieto, J. (2022). EUS-Guided Liver Biopsy in Nonalcoholic Fatty Liver Disease. In: Teoh, A.Y., Giovaninni, M., Khashab, M.A., Itoi, T. (eds) Atlas of Interventional EUS. Springer, Singapore. https://doi.org/10.1007/978-981-16-9340-3_51

Download citation

  • DOI: https://doi.org/10.1007/978-981-16-9340-3_51

  • Published:

  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-16-9339-7

  • Online ISBN: 978-981-16-9340-3

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics