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Exercise in Immune Health Management and Rehabilitation Against COVID-19

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Abstract

There is a challenging time to adopt the “New Normal” of living for the survival of humanity to fight against the pandemic of COVID-19. The new emerging infectious disease caused by severe acute respiratory syndrome (SARS) leads to serious public health risk that resulting to damage immune function within a host. Body has a specific and nonspecific immune mechanism to recognize and eliminate the viral infection. Since it is difficult to avoid completely from being in contact with those who are asymptomatic with positive (active infection), indispensably the host defense mechanism has to be strengthened enough to get optimum functional health by enhancing the body’s natural immunity in the population.

Regular moderate exercise possibly has the potential to play a significant role in immune health care in terms of devising policies of prevention, management, and rehabilitation to deal with the deadly virus. Several studies proved the efficacy of moderate physical exercise in control and management of some lifestyle diseases such as diabetes, hypertension, lung disease, cardiac disease, obesity, cancer, etc., which are also co-morbid conditions in patients with COVID-19. Exercise seems a strong relevance to be useful in vulnerable population such as children, elderly, and immunocompromised persons. Exercise favorably could be a powerful tool of healthy living when people apparently is becoming re-infected and there is no evidence around how long people might remain immune protected after exposure to COVID-19 for which herd immunity has not been achieved by the recovered population.

An ideal moderate exercises program has a great impact on the normal functioning of the immune system for supporting a strong resistance to fight infections against any virus and if infected recover quicker. Exercise is not an alternative to medicines but as supplementary, preventive, therapeutic, and rehabilitative measures to keep COVID-19 type of viral diseases away when vaccine immunity is known very little and while there is a possibility of both recovered and vaccinated persons may later become infected again.

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References

  • Age Appropriate Fitness Protocols and Guidelines, Fit India Mission. (2020). Ministry of Youth Affairs & sports & Ministry of Health & family welfare. MHRD, Govt. of India.

    Google Scholar 

  • Ahmadinejad, Z., Alijani, N., Mansori, S., & Ziaee, V. (2014). Common sportsrelated infections: A review on clinical pictures, management and time to return to sports. Asian Journal of Sports Medicine, 5(1), 1–9. https://doi.org/10.5812/asjsm.34174. [PubMed: 24868426].

    Article  Google Scholar 

  • Ahmed, I. (2020). COVID-19 – does exercise prescription and maximal oxygen uptake (VO2 max) have a role in risk-stratifying patients? Clinical Medicine, 20(3), 28–24.

    Article  CAS  Google Scholar 

  • American College of Sports Medicine. (2018). ACSM’s guidelines for exercise testing and prescription (10th ed.). Wolters Kluwer.

    Google Scholar 

  • Arida, R. M., Cavalheiro, E. A., da Silva, A. C., & Scorza, F. A. (2008). Physical activity and epilepsy:Proven and predicted benefits. Sports Medicine, 38, 607–615.

    Article  Google Scholar 

  • Arida, R. M., Cavalheiro, E. A., & Scorza, F. A. (2012). From depressive symptoms to depression inpeople with epilepsy: Contribution of physical exercise to improve this picture. EpilepsyRes., 99, 1–13.

    Google Scholar 

  • Balchin, R., Linde, J., Blackhurst, D., et al. (2016). Sweating away depression? The impact ofintensive exercise on depression. Journal of Affective Disorders, 200, 218–221.

    Article  Google Scholar 

  • Blocken B, Malizia F, van Druenen T, et al. (2020). Towards aerodynamically equivalent COVID19 1.5 m social distancing for walking and running.

    Google Scholar 

  • Budde, H., Schwarz, R., Velasques, B., Ribeiro, P., Holzweg, M., Machado, S., Brazaitis, M., Staack, F., & Wegner, M. (2016). The need for differentiating between exercise, physical activity, and training. Autoimmun Rev, 110–111. https://doi.org/10.1016/j.autrev.2015.09.004

  • Campbell, J. P., & Turner, J. E. (2018). Debunking the myth of exercise induced immune suppression: Redefining the impact of exercise on immunological health across the lifespan. Frontiers in Immunology, 9, 648.

    Article  Google Scholar 

  • Chen, P., Mao, L., Nassis, G. P., Harmer, P., Ainsworth, B. E., & Li, F. (2020). Wuhan coronavirus (2019-nCoV): The need to maintain regular physical activity while taking precautions. J. Sport Heal. Sci., 9, 103–104. https://doi.org/10.1016/j.jshs.2020.02.001

    Article  Google Scholar 

  • Constandt, B., Thibaut, T., De Bosscher, V., Scheerder, J., Ricour, M., & Willem, A. (2020). Exercising in times of lockdown: An analysis of impact of COVID-19 on levels and patterns of exercise among adults in Belgium. International Journal of Environmental Research and Public Health, 17, 4144.

    Article  CAS  Google Scholar 

  • Davis, J. M., Kohut, M. L., Colbert, L. H., et al. (1997). Exercise, alveolar macrophage function, and susceptibility to respiratory infection. Journal of Applied Physiology, 83, 1461–1466.

    Article  CAS  Google Scholar 

  • Davison, G., Kehaya, C., & Wyn, J. A. (2016). Nutritional and physical activity interventions toimprove immunity. American Journal of Lifestyle Medicine, 10, 152–169.

    Article  Google Scholar 

  • de Araújo, A. L., Silva, L. C. R., Fernandes, J. R., & Benard, G. (2013). Preventing or reversing immunosenescence: Can exercise be an immunotherapy? Immunotherapy, 5, 879–893. https://doi.org/10.2217/imt.13.77

    Article  CAS  Google Scholar 

  • Dwyer, M. J., De Dominicis, S., & Righi, E. (2020). Physical activity: Benefits and challenges during the COVID-19 pandemic. Scandinavian Journal of Medicine & Science in Sports, 30, 1291–1294.

    Article  Google Scholar 

  • Eichner, E. R. (1993). Infection, immunity, and exercise. The Physician and Sportsmedicine, 21(1), 125–135. https://doi.org/10.1080/00913847.1993.11710319. [PubMed: 27414832].

    Article  CAS  Google Scholar 

  • Ekelund, U., Tarp, J., Steene-Johannessen, J., et al. (2019). Dose-response associations between accelerometry measured physical activity and sedentary time and all cause mortality: Systematic review and harmonised meta-analysis. BMJ, 366, l4570.

    Article  Google Scholar 

  • Emery, J.C.; Russell, T.W.; Liu, Y.; Hellewell, J.; Pearson, C.A.B.; Knight, G.M.; Eggo, R.M.; Kucharski, A.J.; Funk, S., CMMID 2019-nCoV Working Group; et al. (2020). The Contribution of Asymptomatic Sars-Cov-2 Infections to Transmission—A Model-Based Analysis of the Diamond Princess Outbreak. CMMID Repository. Retrieved August 7, 2020.

    Google Scholar 

  • Fletcher, G. F., Landolfo, C., Niebauer, J., Ozemek, C., Arena, R., & Lavie, C. J. (2018). Promoting physicalactivity and exercise: JACC health promotion series. J AmColl Cardiol, 72, 1622–1639.

    Article  Google Scholar 

  • Fritz, M. D., Bienz, K. A., Johannes Eckert, D. V. M., Rolf, M., & Zinkernagel, M. D. (2005). Medical microbiology. Thieme.

    Google Scholar 

  • Garber, C. E., Blissmer, B., Deschenes, M. R., Franklin, B. A., Lamonte, M. J., Lee, I. M., Nieman, D. C., & Swain, D. P. (2011). Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: Guidance for prescribing exercise. Medicine and Science in Sports and Exercise, 1334–1359. https://doi.org/10.1249/MSS.0b013e318213fefb

  • Halabchi, F., Ahmadinejad, Z., & Selk-Ghaffari, M. (2020 March). COVID-19 epidemic: Exercise or not to exercise; that is the question! Asian. The Journal of Sports Medicine, 11(1), e102630. https://doi.org/10.5812/asjsm.102630

    Article  Google Scholar 

  • Harris, M. D. (2011). Infectious disease in athletes. Current Sports Medicine Reports, 10(2), 84–89. https://doi.org/10.1249/JSR.0b013e3182142381. [PubMed: 21623289].

    Article  Google Scholar 

  • Hawley, J. A., Hargreaves, M., Joyner, M. J., & Zierath, J. R. (2014). Integrative biology of exercise. Cell, 738–749. https://doi.org/10.1016/j.cell.2014.10.029

  • Hull, J., Loosemore, M., & Schwellnus, M. (2020). Respiratory health in athletes: Facing the COVID-19 challenge. Lancet Resp Med. https://doi.org/10.1016/S2213-2600(20)30175-2

  • Kakanis, M. W., Peake, J., Brenu, E. W., Simmonds, M., Gray, B., Hooper, S. L., & Marshall-Gradisnik, S. M. (2010). The open window of susceptibility to infection after acute exercise in healthy young male elite athletes. Exercise Immunology Review, 16, 119–137. https://doi.org/10.1016/j.jsams.2010.10.642

    Article  CAS  Google Scholar 

  • Keast, D., Cameron, K., & Morton, A. R. (1988). Exercise and the immune response. Sports Medicine, 5, 248–267.

    Article  CAS  Google Scholar 

  • Klimpel, G. R., & Baron, S. (Eds.). (1996). Immune Defenses, medical microbiology (4th ed.). University of Texas Medical Branch at Galveston.

    Google Scholar 

  • Kujala, U. (2009). Evidence on the effects of exercise therapy in the treatment of chronic disease. British Journal of Sports Medicine, 43, 550–555.

    Article  CAS  Google Scholar 

  • La Cava, A., & Matarese, G. (2004). The weight ofleptin in immunity. Nature Reviews Immunology, 4, 371–379.

    Article  Google Scholar 

  • Laddu, D. R., Lavie, C. J., & Phillips, S. A. (2020). Physical activity for immunity protection: Inoculating populations withhealthy living medicine in preparation for the next pandemic. Progress in Cardiovascular Diseases, 3. https://doi.org/10.1016/j.pcad.2020.04.006

  • Lim, M. A., & Pranata, R. (July, 2020). Sports activities during any pandemic lockdown. Irish Journal of Medical Science (1971 -). https://doi.org/10.1007/s11845-020-02300-9

  • Luzi, L., & Radaelli, M. G. (2020). Influenza and obesity: Its odd relationship and the lessons for COVID-19 pandemic. Acta Diabetologica, 57, 759–764. https://doi.org/10.1007/s00592-020-01522-8

    Article  CAS  Google Scholar 

  • Martin, S. A., Pence, B. D., & Woods, J. A. (2009). Exercise and respiratory tract viral infections. Exerc SportSci Rev., 37(4), 157–164. https://doi.org/10.1097/JES.0b013e3181b7b57b

    Article  Google Scholar 

  • McCloskey, B., & Heymann, D. L. (2020). SARS to novel coronavirus - old lessons and new lessons. Epidemiology and Infection, 148, e22.

    Article  CAS  Google Scholar 

  • Medline Plus, Exercise and immunity. (2020). Retrieved March 15, 2020, from https://medlineplus.gov/ency/article/007165.htm

  • Mousavizadeh, L., & Ghasemi, S. (2020). Genotype and phenotype of COVID-19: Their roles in pathogenesis. Journal of Microbiology, Immunology, and Infection. https://doi.org/10.1016/j.jmii.2020.03.022. Published online.

  • Nieman, D. C., & Wentz, L. M. (2019). The compelling link between physical activity and the body’sdefense system. Journal of Sport and Health Science, 8, 201–217.

    Article  Google Scholar 

  • Peake, J. M., Neubauer, O., Walsh, N. P., & Simpson, R. J. (2017). Recovery of the immune system after exercise. J. Appl. Physiol., 122, 1077–1087. https://doi.org/10.1152/japplphysiol.00622.2016

    Article  CAS  Google Scholar 

  • Pedersen, B. K., & Saltin, B. (2015). Exercise as medicine - evidence for prescribing exercise astherapy in 26 different chronic diseases. Scandinavian Journal of Medicine & Science in Sports, 3, 1–72.

    Article  Google Scholar 

  • Pedersen, B. K., & Ullum, H. (1994). NK cell response to physical activity: Possible mechanisms of action. Medicine and Science in Sports and Exercise, 26, 140–146.

    Article  CAS  Google Scholar 

  • Philippe, M., Gatterer, H., Burtscher, M., Weinberger, B., Keller, M., Grubeck-Loebenstein, B., et al. (2019). Concentric and eccentric endurance exercise reverse hallmarks of T-cell senescence in pre-diabetic subjects. Frontiers in Physiology, 10, 684. https://doi.org/10.3389/fphys.2019.00684

    Article  Google Scholar 

  • Radogna, E., Diederich, M., & Ghibelli, L. (2010). Melatonin: a pleiotropic molecule regulating inflammation. Biochemical Pharmacology, 80, 1844–1852.

    Article  CAS  Google Scholar 

  • Sallis, J. F., Adlakha, D., Oyeyemi, A., et al. (2020). An international physical activity and public health research agenda to inform coronavirus disease-2019 policies and practices. Journal of Sport and Health Science, 9, 328–334.

    Article  Google Scholar 

  • Simpson, R., Kunz, H., Agha, N., & Graff, R. (2015). Exercise and the regulation of immune functions 2015. Progress in Molecular Biology and Translational Science, 135, 355–380.

    Article  Google Scholar 

  • Simpson, R. J. (30 March, 2020). Exercise, immunity and the COVID-19 pandemic. Accessed Mar 3, 2022, from https://www.acsm.org/blog-detail/acsm-blog/2020/03/30/exercise-immunity-covid-19-pandemic

  • Siordia, J. A., Jr. (2020). Epidemiology and clinical features of COVID-19: A review of current literature. Journal of Clinical Virology, 127, 104357. https://doi.org/10.1016/j.jcv.2020.104357

    Article  CAS  Google Scholar 

  • Vancini, R. L., Andrade, M. S., & de Lira, C. A. (2016). Exercise as medicine for people with epilepsy. Scandinavian Journal of Medicine & Science in Sports, 26, 856–857.

    Article  CAS  Google Scholar 

  • Vina, J., Sanchis-Gomar, F., Martinez-Bello, V., et al. (2012). Exercise acts as a drug; thepharmacological benefits of exercise. British Journal of Pharmacology, 167(1), 1–12.

    Article  CAS  Google Scholar 

  • Walsh, N. P., Gleeson, M., Shephard, R. J., Gleeson, M., Woods, J. A., Bishop, N. C., Fleshner, M., Green, C., Pedersen, B. K., Hoffman-Goetz, L., Rogers, C. J., Northoff, H., Abbasi, A., & Simon, P. (2011). Position statement part one: immune function and exercise. Exercise Immunology Review, 17, 6–63.

    Google Scholar 

  • Wong, C.-M., Lai, H.-K., Ou, C.-Q., et al. (2008). Is exercise protective against influenza-associated mortality? PLoS One, 3, e2018.

    Article  Google Scholar 

  • Woods, J. A., & Davis, J. M. (1994). Exercise, monocyte/macrophage function, and cancer. Medicine and Science in Sports and Exercise, 26, 147–157.

    Article  CAS  Google Scholar 

  • Zhu, W. (2020). Should, and how can, exercise be done during a coronavirus outbreak? An interview withDr. Jeffrey A. Woods. Journal of Sport and Health Science, 9, 105–107. https://doi.org/10.1016/j.jshs.2020.01.005

    Article  Google Scholar 

  • Zou, L., Luan, F., Huang, M., Hong, Z., Yu, J., Kang, M., Yu, J., Kang, M., Song, Y., Xia, J., et al. (2020). SARS-CoV-2 viral load in upper respiratory specimens of infected patients. The New England Journal of Medicine, 382, 12.

    Article  Google Scholar 

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Acknowledgments

The authors are thankful to Jadavpur University RUSA 2.0 Major Research Support and University Grant Commission (UGC), Govt. of India. The authors thankfully acknowledge cooperation and help extended by the Office Staff of the Director of Physical Instruction, members of Sports Board, Physical Education department and Jadavpur University authority. The authors are grateful to Prof. Sadhan Kumar Ghosh, Professor & Former Head, Mechanical Engineering Department and Ex-Dean, Faculty of Engineering and Technology, Jadavpur University, Kolkata, India for his expertise and valuable suggestions for smooth conduction of this study.

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Correspondence to Aparup Konar .

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Konar, A., Mondal, S. (2022). Exercise in Immune Health Management and Rehabilitation Against COVID-19. In: Ghosh, S.K., Agamuthu, P. (eds) Health Care Waste Management and COVID 19 Pandemic. Springer, Singapore. https://doi.org/10.1007/978-981-16-9336-6_14

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