Abstract
A bioreactor is a manufactured device or system that helps to produce biologically active substances such as yeast, bacteria, or mammalian cells under controlled environment. Bioreactor is basically a vessel constructed where chemical process is carried out in the presence of cells or organisms to produce large quantity of cells or their byproducts. The need for bioreactors arises when you need to produce large quantity of biological products, which is however not possible in the research laboratories. These bioreactors come with various sizes ranging from 2 L to 100s of L. These bioreactors are used to produce biopharmaceuticals, vaccines, or monoclonal antibodies, cell production and expansion, enzyme production, tissue engineering, algae production, protein synthesis, and also stem cell production. In this chapter, we will discuss significance, application, design, types, and operation of bioreactor especially focusing to mammalian or stem cell culture.
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Khan, F.A. (2022). Stem Cell Bioreactors: Design, Structure, and Operation of Stem Cell Bioreactors. In: Khan, F.A. (eds) Stem Cell Production. Springer, Singapore. https://doi.org/10.1007/978-981-16-7589-8_5
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DOI: https://doi.org/10.1007/978-981-16-7589-8_5
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